http://www.labmanager.com/ Lab Manager Magazine Article RSS Feed for Technology en-us ©2011 LabManager, a division of the LabX Media Group. All Rights Reserved. Tue, 21 May 2013 11:40:00 EST 120 http://www.labmanager.com//images/site/LabManagerPrintLogo.jpg http://www.labmanager.com/ http://www.labmanager.com//?articles.view/articleNo/35339/article/Managing-R-D-Data-in-a-Virtual-World http://www.labmanager.com//?articles.view/articleNo/35339/article/Managing-R-D-Data-in-a-Virtual-World Pharmaceutical and biotech companies are moving from centralized organizations to a virtual network of contract research organizations (CROs), academic partners, internal labs, and government agencies. Access to real-world patient data, supporting precision or stratified drug discovery, and the general trend to externalize services all require sophisticated data management that enables the right mix of access and security. This article will look at the different research and development (R&D) processes in life science organizations where data is central to collaboration, and how it needs to be consistently captured, integrated, managed, tracked, and analyzed. Technical considerations for supporting this changing environment will also be explored and, as pharmaceutical companies are already in this increasingly complex network of data and partners, this will be done in a pragmatic way. Technology Thu, 02 May 2013 00:00:00 EST http://www.labmanager.com//?articles.view/articleNo/34924/article/Energy-Improvements http://www.labmanager.com//?articles.view/articleNo/34924/article/Energy-Improvements Laboratories in the U.S. are energy-intensive facilities that use anywhere from 30 to 100 kilowatt-hours (kWh) of electricity and 75,000 to 800,000 Btu of natural gas per square foot annually. Actual use varies with such factors as the age of the facility, the type of research done there, and the climate zone in which the lab is located. In a typical laboratory, lighting and space heating account for approximately 74 percent of total energy use (Figure 1), making these systems the best targets for energy savings. Because laboratories consume so much energy, the potential for energy and dollar savings through energy-efficiency improvements and energy conservation is impressive—some studies estimate that implementing such measures can result in savings as high as 50 percent for laboratories and cleanroom facilities. Technology Thu, 04 Apr 2013 00:00:00 EST http://www.labmanager.com//?articles.view/articleNo/34493/article/HPC-Storage-Solutions http://www.labmanager.com//?articles.view/articleNo/34493/article/HPC-Storage-Solutions Do you like Pringles™ potato chips? Do you use skin lotion? Have you noticed all the new planets outside our solar system that have been recently discovered? When you’ve flown, have you noticed the funny tails that are on the wing tips? Have you seen the new cancer-fighting drugs that are tailored to individuals and their tumors? All these things and many others are made possible by HPC (high performance computing). HPC is quickly becoming an important tool in many companies, research institutes, and universities. Technology Tue, 05 Mar 2013 00:00:00 EST http://www.labmanager.com//?articles.view/articleNo/34530/article/Prepared-for-Power-Failure- http://www.labmanager.com//?articles.view/articleNo/34530/article/Prepared-for-Power-Failure- Although the concept of a checklist has been regarded as a foundation of standardization and operational safety in government and industry services for some time, such techniques have generally escaped the scrutiny of the human factor industry. Most laboratory operators budgeting for and installing new equipment tend to overlook key elements of their projects. This oversight results in missing the full scope of the required tasks, which usually lands the laboratory or project manager on the short side of funding, time, materials, and human resources when contemplating and/ or installing a capital improvement project. Technology Tue, 05 Mar 2013 00:00:00 EST http://www.labmanager.com//?articles.view/articleNo/34051/article/Fixing-the-Top-8-Lab-Chemical-Management-Errors http://www.labmanager.com//?articles.view/articleNo/34051/article/Fixing-the-Top-8-Lab-Chemical-Management-Errors Step One: Get your chemical inventory under control In October 2012, Lab Manager Magazine, along with ChemSW Inc., hosted a Product Spotlight webinar, "How to Find and Fix the Top Eight Lab Chemical Management Errors."  Jon Webb, senior technical specialist and inventory consultant at ChemSW, gave a brief presentation on the challenges of chemical inventory and data management and outline some of the common errors that exist in labs today. He discussed best practices in chemical inventory... Technology Thu, 24 Jan 2013 00:00:00 EST http://www.labmanager.com//?articles.view/articleNo/34050/article/Labs-are-from-Mars--IT-Departments-are-from-Venus http://www.labmanager.com//?articles.view/articleNo/34050/article/Labs-are-from-Mars--IT-Departments-are-from-Venus Understanding each other's needs and priorities is key to a good working relationship Technology Wed, 23 Jan 2013 00:00:00 EST http://www.labmanager.com//?articles.view/articleNo/34063/article/ASK-THE-EXPERT---Trends-in-Bioinformatics http://www.labmanager.com//?articles.view/articleNo/34063/article/ASK-THE-EXPERT---Trends-in-Bioinformatics Joel Dudley, Ph.D., Assistant Professor of Genetics and Genomic Sciences and Director of Biomedical Informatics at Mount Sinai School of Medicine, talks to contributing editor Tanuja Koppal, Ph.D. about the current changes impacting bioinformatics. While data generation gets simpler and less expensive, data search and interpretation remain a formidable challenge. Lack of standardization in data nomenclature and analysis tools continues to spur innovation in the creation of custom software programs and services. Since there exists no easy, one-stop shop for data management, Dudley advises lab managers to leverage their core facilities for bioinformatics, to look out for emerging software companies, and to get creative with informatics tools when tackling complex integrative biology. Technology Wed, 23 Jan 2013 00:00:00 EST http://www.labmanager.com//?articles.view/articleNo/33412/article/It-s-all-in-the-Planning--How-Smart-Lab-Design-and-Layout-Ensure-Optimal-Procedures--Workflow--Cooperation-and-Productivity http://www.labmanager.com//?articles.view/articleNo/33412/article/It-s-all-in-the-Planning--How-Smart-Lab-Design-and-Layout-Ensure-Optimal-Procedures--Workflow--Cooperation-and-Productivity There are varying points of view on the question of the best use of research space. Different stakeholder groups hold differing views, and individuals within these groups will have different sets of priorities. But the same goal is shared by all: arrangement and layout should promote successful scientific research and the well-being of the researchers. Technology Mon, 10 Dec 2012 00:00:00 EST http://www.labmanager.com//?articles.view/articleNo/33413/article/Optimizing-Laboratory-Operations--Asset-Utilization-Monitoring-Captures-the-Data-Necessary-to-Improve-Instrument-Uptime-and-Lab-Productivity http://www.labmanager.com//?articles.view/articleNo/33413/article/Optimizing-Laboratory-Operations--Asset-Utilization-Monitoring-Captures-the-Data-Necessary-to-Improve-Instrument-Uptime-and-Lab-Productivity To optimize lab operations, several questions must first be answered. How can you adjust service levels based on usage? How can you trigger preventive actions prior to failure? How effective are you at utilizing your assets? Technology Mon, 10 Dec 2012 00:00:00 EST http://www.labmanager.com//?articles.view/articleNo/33478/article/Technology-News http://www.labmanager.com//?articles.view/articleNo/33478/article/Technology-News UV/Visible Spectrophotometers • Classical-looking UV-Vis spectrophotometers now include enhanced standard features • Certain models now include free DataStream PC control software, free validation software, free single cell Kinetics software and free automatic cell changer software • Each instrument will also be supplied with an appropriate dust cover • A wide range of additional features is also available Technology Mon, 10 Dec 2012 00:00:00 EST http://www.labmanager.com//?articles.view/articleNo/33082/article/The-Second-Annual-Laboratory-Spending-Trends-Report---Another-Year-of-Low-Growth-Laboratory-Product-Budgets-Anticipated-in-2013 http://www.labmanager.com//?articles.view/articleNo/33082/article/The-Second-Annual-Laboratory-Spending-Trends-Report---Another-Year-of-Low-Growth-Laboratory-Product-Budgets-Anticipated-in-2013 With the “fiscal cliff ” looming—the possibility that substantial portions of the U.S. federal budget will be trimmed in 2013— laboratories that depend on government money are anticipating sharply constrained budgets. Magazine, Management, Technology Fri, 09 Nov 2012 00:00:00 EST http://www.labmanager.com//?articles.view/articleNo/33134/article/Mass-Spectrometry-Today---Fast-Growing--Innovative--But-Still-Somewhat-Enigmatic http://www.labmanager.com//?articles.view/articleNo/33134/article/Mass-Spectrometry-Today---Fast-Growing--Innovative--But-Still-Somewhat-Enigmatic The mass spectrometry (MS) market continues to be one of the fastest-growing areas of analytical instrumentation. MS’s growing popularity can be explained by its ability to provide, in many cases, verifiable molecular weights and thereby positive identification of known molecules. Technology Fri, 09 Nov 2012 00:00:00 EST http://www.labmanager.com//?articles.view/articleNo/33203/article/Technology-News http://www.labmanager.com//?articles.view/articleNo/33203/article/Technology-News Smart Spectrometers Exemplar LS & Exemplar Plus • A good fit for applications such as high speed reaction kinetics, laser-induced breakdown spectroscopy, and real-time process monitoring • Feature a low stray light “unfolded” Czerny-Turner spectrograph to provide excellent performance, particularly below 400nm • LS model provides all of the advantages of the low straylight spectrograph while still retaining a small form factor; Plus model provides increased focal length Technology Fri, 09 Nov 2012 00:00:00 EST http://www.labmanager.com//?articles.view/articleNo/32756/article/Ask-the-Expert--Choosing-the-Right-IT-System-and-Data-Infrastructure http://www.labmanager.com//?articles.view/articleNo/32756/article/Ask-the-Expert--Choosing-the-Right-IT-System-and-Data-Infrastructure Alexander Sherman, director of systems in the Department of Neurology and director of strategic development and systems at the Neurological Clinical Research Institute at Massachusetts General Hospital, discusses why the right choice and setup for data collecting, data handling, and data sharing infrastructure is important to help establish successful research collaborations. LabManager, Lab Management, Magazine, Management, Technology Sat, 06 Oct 2012 00:00:00 EST http://www.labmanager.com//?articles.view/articleNo/30464/article/Perspective-On--A-Mobile-Lab http://www.labmanager.com//?articles.view/articleNo/30464/article/Perspective-On--A-Mobile-Lab Born of the anthrax mailing scare of 2002, the mobile lab in the hazardous materials section of the Cleveland Fire Department in Ohio deals with public health risks and the identification of unknown, potentially dangerous substances in the region. Technology Fri, 05 Oct 2012 00:00:00 EST http://www.labmanager.com//?articles.view/articleNo/30478/article/Preventing-Cell-Death http://www.labmanager.com//?articles.view/articleNo/30478/article/Preventing-Cell-Death The cell wall components of gram-negative bacteria, such as E. coli and pseudomonads, are designated as endotoxins. They have a hydrophilic polysaccharide and a lipophilic lipid component and, unlike the bacteria from which they originate, are Technology Wed, 03 Oct 2012 00:00:00 EST http://www.labmanager.com//?articles.view/articleNo/30248/article/Building-Transparency--A-Bottom-Up-View http://www.labmanager.com//?articles.view/articleNo/30248/article/Building-Transparency--A-Bottom-Up-View How strategically integrating informatics tools across a drug discovery workflow can improve transparency, trust and productivity This is Part II of a two-part series. The goal of an informatics project implemented in the drug discovery Technology Fri, 07 Sep 2012 00:00:00 EST http://www.labmanager.com//?articles.view/articleNo/30256/article/Repair--Maintenance--and-Calibration--Oh-My- http://www.labmanager.com//?articles.view/articleNo/30256/article/Repair--Maintenance--and-Calibration--Oh-My- Designing the most cost-effective and efficient instrument service program requires careful consideration Just as instrument technology evolves to meet the changing needs of research, so does instrument maintenance evolve as lab managers seek Technology Wed, 05 Sep 2012 00:00:00 EST http://www.labmanager.com//?articles.view/articleNo/8082/article/Perspective-On--A-Drug-Discovery-Lab http://www.labmanager.com//?articles.view/articleNo/8082/article/Perspective-On--A-Drug-Discovery-Lab Started up in 2000, A&G Pharmaceutical is an antibody-based drug theranostic (therapeutic and diagnostic) company focused on improving the screening, detection, and treatment of cancer as well as other diseases that affect people. Based in Technology Mon, 09 Jul 2012 00:00:00 EST http://www.labmanager.com//?articles.view/articleNo/8090/article/Flexible-Gas-Handling http://www.labmanager.com//?articles.view/articleNo/8090/article/Flexible-Gas-Handling Specifying gas handling systems that are as expandable as a child?s LEGOŽ set is a reality today, thanks to innovative systems designed for laboratory use with flexibility in mind. By using switchovers, manifolds, and the like, you can Technology Mon, 09 Jul 2012 00:00:00 EST http://www.labmanager.com//?articles.view/articleNo/8087/article/Lab-Automation-is-Inevitable http://www.labmanager.com//?articles.view/articleNo/8087/article/Lab-Automation-is-Inevitable In September 2012, the Institute for Laboratory Automation and Lab Manager Magazine? as part of the Lab Automation University program? will offer a series of webinars under the heading ?Lab Automation Is Inevitable: Are You Technology Fri, 06 Jul 2012 00:00:00 EST http://www.labmanager.com//?articles.view/articleNo/8089/article/Field-Worthy-Instrumentation http://www.labmanager.com//?articles.view/articleNo/8089/article/Field-Worthy-Instrumentation Portable instrumentation and analyzers are a booming business if recent announcements are any guide. Rigaku?s handheld Raman spectrometer, Thermo Fisher?s handheld X-ray and Raman analyzers, Centice Corp.?s Raman-based narcotics Technology Fri, 06 Jul 2012 00:00:00 EST http://www.labmanager.com//?articles.view/articleNo/7800/article/Perspective-On--A-Food-and-Beverage-Lab http://www.labmanager.com//?articles.view/articleNo/7800/article/Perspective-On--A-Food-and-Beverage-Lab Headquartered in the Livermore Valley in Northern California, the National Food Lab (NFL) is more than just a food and beverage testing facility. “We really are a full-service research and consulting company for the food industry, starting Technology Wed, 06 Jun 2012 00:00:00 EST http://www.labmanager.com//?articles.view/articleNo/7788/article/Building-Transparency---A-Top-Down-View http://www.labmanager.com//?articles.view/articleNo/7788/article/Building-Transparency---A-Top-Down-View Drug discovery is an inherently collaborative venture that necessitates the interaction and integration of people, processes, laboratories, and technology. This is easier said than done, however. Technology Mon, 04 Jun 2012 00:00:00 EST http://www.labmanager.com//?articles.view/articleNo/7485/article/Information-Technology-and-Your-Workforce http://www.labmanager.com//?articles.view/articleNo/7485/article/Information-Technology-and-Your-Workforce From a utilitarian standpoint, it was inevitable that technology would redefine the processes of the modern lab. It began with the need to automate as suppliers realized they could help labs significantly improve their products by taking Technology Wed, 09 May 2012 00:00:00 EST http://www.labmanager.com//?articles.view/articleNo/7501/article/Perspective-On--An-Environmental-Research-Lab http://www.labmanager.com//?articles.view/articleNo/7501/article/Perspective-On--An-Environmental-Research-Lab Clean Harbors of Baltimore, Inc., is a transfer storage and disposal facility and part of the largest hazardous waste disposal company in North America. Clean Harbors provides recycling, treatment and disposal of a variety of hazardous and Technology Wed, 09 May 2012 00:00:00 EST http://www.labmanager.com//?articles.view/articleNo/7502/article/No-Interference http://www.labmanager.com//?articles.view/articleNo/7502/article/No-Interference As samples become increasingly active and more complex, labs simply cannot afford interferences caused by flow path activity in their GCs. A non-inert flow path can cause peak tailing and signal loss. It can also hide parts of samples, so users Technology Wed, 09 May 2012 00:00:00 EST http://www.labmanager.com//?articles.view/articleNo/7482/article/-Appifying--the-Laboratory http://www.labmanager.com//?articles.view/articleNo/7482/article/-Appifying--the-Laboratory For many techies, the launch of Apple?s App Store was like shooting off a starter?s pistol for today?s unrelenting apps race.... Technology Wed, 02 May 2012 00:00:00 EST http://www.labmanager.com//?articles.view/articleNo/7504/article/Faster-Turnaround-Means-Happier-Customers http://www.labmanager.com//?articles.view/articleNo/7504/article/Faster-Turnaround-Means-Happier-Customers Managing the pace of technological change that defines next-generation sequencing (NGS) isn?t just an issue for NGS labs. It also challenges the makers of NGS instrumentation. Technology Wed, 02 May 2012 00:00:00 EST http://www.labmanager.com//?articles.view/articleNo/7302/article/Perspective-On--A-Biofuel-Research-Laboratory http://www.labmanager.com//?articles.view/articleNo/7302/article/Perspective-On--A-Biofuel-Research-Laboratory Even before the current cloudier tax incentive climate cast its shadow on biofuel production, the budding industry faced the slings and arrows of environmentalists, food producers and even applied economists. The renewability of biomass stock feeds Technology Fri, 06 Apr 2012 00:00:00 EST http://www.labmanager.com//?articles.view/articleNo/7306/article/Improving-Sustainability http://www.labmanager.com//?articles.view/articleNo/7306/article/Improving-Sustainability Many companies have made the decision to improve the sustainability of their operations, facilities, and products. They are doing so in response to a variety of pressures, including shareholder demand, employee interest, the potential for cost Technology Fri, 06 Apr 2012 00:00:00 EST http://www.labmanager.com//?articles.view/articleNo/7304/article/Automatic-Identification http://www.labmanager.com//?articles.view/articleNo/7304/article/Automatic-Identification Performance and productivity expectations for the modern laboratory have never been higher. Test results must be accurate, timely, and provided in the most cost-effective way possible. Fortunately for lab managers, automation technology has advanced. Technology Tue, 03 Apr 2012 00:00:00 EST http://www.labmanager.com//?articles.view/articleNo/7305/article/Managing-Chemical-Inventory http://www.labmanager.com//?articles.view/articleNo/7305/article/Managing-Chemical-Inventory The old proverb ?The more things change, the more they stay the same? seems truer than ever. Certainly, the use of technology in the lab is making significant changes to laboratory work processes, but when all is said and done, the goals of the Technology Tue, 03 Apr 2012 00:00:00 EST http://www.labmanager.com//?articles.view/articleNo/7025/article/Planned-Downtime http://www.labmanager.com//?articles.view/articleNo/7025/article/Planned-Downtime Routine maintenance and proper training can extend the life of any piece of laboratory equipment. Unfortunately, even with proper maintenance, and sometimes resulting from lack of maintenance, large equipment can break down?sometimes at the Technology Mon, 05 Mar 2012 00:00:00 EST http://www.labmanager.com//?articles.view/articleNo/7032/article/HPLC-Fluorescence-Detection http://www.labmanager.com//?articles.view/articleNo/7032/article/HPLC-Fluorescence-Detection Although scientists have relied solely on LC-MS methods in recent years, HPLC-fluorescence detection is now designated as the official analysis method for many components across various industries. In particular, it is used for analyses that Technology, HPLC Systems Fri, 02 Mar 2012 00:00:00 EST http://www.labmanager.com//?articles.view/articleNo/6642/article/The-Evolving-Service-Model http://www.labmanager.com//?articles.view/articleNo/6642/article/The-Evolving-Service-Model Faced with shrinking budgets, laboratory managers are constantly seeking more effective ways to service and maintain their equipment, which they must now keep operational over lengthening life spans. Providing much-needed respite in this challeng Home, Technology Fri, 20 Jan 2012 00:00:00 EST http://www.labmanager.com//?articles.view/articleNo/6644/article/Ask-The-Expert--The-Economic-Benefits-of-Lab-Automation http://www.labmanager.com//?articles.view/articleNo/6644/article/Ask-The-Expert--The-Economic-Benefits-of-Lab-Automation Sukhanya Jayachandra, Ph.D., Senior Research Investigator and head of the Cellular Resource Group, Lead Discovery Profiling Compound Management at Bristol-Myers Squibb (BMS), talks to contributing editor Tanuja Koppal, Ph.D., about her cell culture Home, Technology Fri, 20 Jan 2012 00:00:00 EST http://www.labmanager.com//?articles.view/articleNo/6684/article/Perspective-On--A-Forenics-Lab http://www.labmanager.com//?articles.view/articleNo/6684/article/Perspective-On--A-Forenics-Lab Stephanie Smith has an exciting job. As assistant lab director of the Physical Sciences Unit at the National Forensics Laboratory of the United States Postal Inspection Service (USPIS)?the law enforcement arm of the United States Postal Service Home, Technology Fri, 20 Jan 2012 00:00:00 EST http://www.labmanager.com//?articles.view/articleNo/6643/article/The-Analytical-Lifecycle-Approach http://www.labmanager.com//?articles.view/articleNo/6643/article/The-Analytical-Lifecycle-Approach Analytical methods are at the core of demonstrating the quality of pharmaceutical products. When these methods fail to perform as expected, the quality of these products is called into question. Certainly, we expect to identify quality issues if they Technology Wed, 18 Jan 2012 00:00:00 EST http://www.labmanager.com//?articles.view/articleNo/6658/article/Integrating-Systems http://www.labmanager.com//?articles.view/articleNo/6658/article/Integrating-Systems ?Integration? within lab automation is a bit like the word ?free? in a store window: It gets your attention and you want to find out more; sometimes you?re glad you did and other times not. The reason it grabs our attent Technology Wed, 18 Jan 2012 00:00:00 EST http://www.labmanager.com//?articles.view/articleNo/6346/article/Advantages-Offered-by-Integrated-Systems http://www.labmanager.com//?articles.view/articleNo/6346/article/Advantages-Offered-by-Integrated-Systems Increased Productivity: You spend your time conducting research, not on complex system or data integration. Improved Collaboration: Integrated systems operate in a browser-based environment over the cloud. Authorized users in different location Technology Fri, 09 Dec 2011 00:00:00 EST http://www.labmanager.com//?articles.view/articleNo/6349/article/Adapting-to-Scientific-Mobility http://www.labmanager.com//?articles.view/articleNo/6349/article/Adapting-to-Scientific-Mobility This column over the last year has dealt with many lab-related workforce issues, but one constant running through them has been the need for versatilability??not just when it comes to the people managers hire, but in every aspect of a lab Management, Technology Fri, 09 Dec 2011 00:00:00 EST http://www.labmanager.com//?articles.view/articleNo/6371/article/Perspective-On--A-Food-Testing-Lab http://www.labmanager.com//?articles.view/articleNo/6371/article/Perspective-On--A-Food-Testing-Lab Developers of analytical instrumentation for food laboratories are constantly being kept on their toes?foremost by the competing technical advancements and expanding market demands inherent in their business, and also by the need to help cust Home, Technology, Gas Chromatography Systems , Mass Spectrometers, Spectrophotometers Wed, 07 Dec 2011 00:00:00 EST http://www.labmanager.com//?articles.view/articleNo/6335/article/Clean-Chemistry-Tools http://www.labmanager.com//?articles.view/articleNo/6335/article/Clean-Chemistry-Tools In recent years there have been continued developments in instrumentation for trace metals analysis?particularly in ICP-OES and ICP-MS. Current ICP-OES instruments are capable of ppt level detection limits for many elements, while the developme Home, Technology Tue, 06 Dec 2011 00:00:00 EST http://www.labmanager.com//?articles.view/articleNo/6337/article/Integrated-Tools-Harmonize-Disparate-Datasets http://www.labmanager.com//?articles.view/articleNo/6337/article/Integrated-Tools-Harmonize-Disparate-Datasets Consolidation, collaboration and configurability seem to be the three C?s driving the need for more tightly integrated lab workflows and systems, especially in the life science market. Increased consolidation in the pharmaceutical and biotechno Technology Tue, 06 Dec 2011 00:00:00 EST http://www.labmanager.com//?articles.view/articleNo/5936/article/The-Power-of-Portability http://www.labmanager.com//?articles.view/articleNo/5936/article/The-Power-of-Portability Over the past year, the trends in portable instrumentation that we first explored in July 2010 have continued to progress, with devices getting smaller, faster, and more powerful as demand for portability remains high. However, there have been a few Home, Technology Fri, 04 Nov 2011 00:00:00 EST http://www.labmanager.com//?articles.view/articleNo/5940/article/Controlling-Airflow-in-Class-II-Biosafety-Cabinets http://www.labmanager.com//?articles.view/articleNo/5940/article/Controlling-Airflow-in-Class-II-Biosafety-Cabinets Sensor-based feedback loops In the late 1970s and early 1980s, the increased availability and reduced cost of electronic air velocity sensors made sensor-based feedback loops a viable solution for biosafety cabinet manufacturers. The first of the Technology Thu, 03 Nov 2011 00:00:00 EST http://www.labmanager.com//?articles.view/articleNo/5761/article/Moving-Molecular-Diagnostics-from-Bench-to-Clinic http://www.labmanager.com//?articles.view/articleNo/5761/article/Moving-Molecular-Diagnostics-from-Bench-to-Clinic The function of molecular diagnostics is to analyze the composition of a patient?s genetic makeup in order to reveal any potential predispositions of that individual to specific diseases. Identifying these biomarkers can allow treatment options Technology Tue, 04 Oct 2011 00:00:00 EST http://www.labmanager.com//?articles.view/articleNo/5769/article/Making-ChIP-Sequencing-User-Friendly http://www.labmanager.com//?articles.view/articleNo/5769/article/Making-ChIP-Sequencing-User-Friendly Chromatin states can influence transcription directly by altering the packaging of DNA to allow or prevent access to DNA-binding proteins, or they can modify the nucleosome surface to enhance or impede recruitment of effector protein complexes. Genom Technology Tue, 04 Oct 2011 00:00:00 EST http://www.labmanager.com//?articles.view/articleNo/5091/article/Next-Generation-Sequencing-Hype-Confirmed http://www.labmanager.com//?articles.view/articleNo/5091/article/Next-Generation-Sequencing-Hype-Confirmed Perhaps the most buzz-worthy technology in life sciences, next-generation sequencing continues to undergo rapid changes. With vendors updating their portfolios with new instruments annually, the market remains highly competitive and dynamic. The edit Technology Fri, 09 Sep 2011 00:00:00 EST