Mike May is a freelance writer and editor living in Austin, TX. You may reach him at mike@techtyper.com.
Published: May 8 2013
Many industries measure viscosity. “The use of viscometers runs the gamut,” says Robert McGregor, general manager of marketing and sales for high-end lab instruments at Brookfield Engineering (Middleboro, MA). “The biggest user is the quality control department using single-point measurement.” Research scientists also use viscometers to see how a material reacts to being sheared.
Published: May 8 2013
To measure the rotation of linearly polarized light going through an optically active or chiral molecule, researchers use a polarimeter. As Alex White, product specialist at Anton Paar USA (Ashland, VA), says, “There is now more demand for polarimeters in all industries that use or need to measure optically active samples, as polarimeters have the capability of being very accurate, precise, robust, and user-friendly.” He adds, “Anton Paar has seen significant growth in polarimeter sales, particularly in the pharmaceutical, food, and flavor and fragrance industries. This demand has in turn led to more requests from universities to use our polarimeters for research.”
Published: May 8 2013
The history of microplate readers— now on the market for more than 30 years—explains the ongoing increase in applying this technology. Plate readers are used in many applications, including bioassay development, diagnostics, drug discovery, food testing, and quality control. The expanding range of applications parallels the large number of detection modes, including absorbance, AlphaScreen, fluorescence polarization, time-resolved fluorescence (TRF), time-resolved fluorescence energy transfer (TR-FRET), luminescence, and spectrophotometry. In a survey by Lab Manager, 90 percent of the respondents used absorbance detection and roughly threequarters also used AlphaScreen and fluorescence polarization.
Published: April 8 2013
Published: April 8 2013
Evaporators are a common
Published: April 4 2013
Papers, Ph.D. students, and so on make up the traditional outputs of science laboratories, but these days energy consumption matters more and more. That consumption includes the energy to condition the air and drive the analytical platforms. Disposable plastic, reagents, and other items also contribute to a lab’s consumption. Those consumables raise growing concerns as labs around the world strive to be more efficient, more “green.” Today’s vendors supply more options than ever to build a green operation. Nonetheless, much more work needs to be done to modernize labs.
Published: March 9 2013
Assays from academics to industry require shakers. In the life sciences, for example, Ira Augenzucker, product line manager at Labnet International, a Corning Life Sciences company in Edison, NJ, says, “The new uses of shakers basically mimic what you see in the industry, which is an increase in the use of genomics.” He adds, “Shakers are used in almost every application in some fashion.” For example, he points out the wide use of shakers in cell culture work.
Published: March 5 2013
A glove box consists of a sealed box with the inside accessible only by gloves. “Although their use is getting broader all the time,” says Laura Geenen, product manager at Bel-Arts Products (Wayne, NJ), “they are really used for two basic ideas: Protect what you work on from the environment, such as an analytic balance on a production floor, or protect you from what you work on, such as a virus.”
Published: January 30 2013
Filtration makes up a key procedure in a wide range of laboratories, from basic biological and chemical research to industrial applications, including food processing, pharmaceuticals, and more.
Published: January 30 2013
Researchers use stirrers for many laboratory applications, from dissolving powders to mixing reagents. To get the right results, it takes more than placing a stir bar into a vessel and turning on the stirring device.
Published: December 10 2012
To grow a culture of bacteria, researchers typically use an incubator. The so-called non-gassed or microbiological incubators come in many styles, and usually provide temperature options of 5 to 70 degrees Celsius, although most researchers grow bacteria at 37 degrees Celsius.
Published: December 6 2012
To culture cells reproducibly, scientists seek a consistently controlled environment. “At the end of the day, a customer just wants to grow cells,” says Uwe Ross, president at BINDER (Bohemia, NY).
Published: December 4 2012
Few labs these days could survive without pipettes. Many assays require pipetting, and the increasing size of multiwell plates demands more steps than ever.
Published: December 4 2012
Scientists use models to unravel how something works. If you’ve ever taken variously sized balls and arranged them as the planets in our solar system, then you’ve made a model.
Published: November 9 2012
In 1950, the late biochemist Lyman C. Craig of The Rockefeller University developed a simple rotary evaporator. The first commercial version came from Walter Buchi in 1957.
Published: November 6 2012
Once when helping a friend do the dinner dishes, she said, “You wash them so thoroughly.” I laughed and said, “I wash dishes like lab glassware.”
Published: November 5 2012
To grind something solid, many of us might think of a mortar and pestle as the original grinding machine. In fact, that technology goes back at least to 1550 BCE, when one was described in Egyptian writing. Many other hand-powered mills and grinders followed, leading to powered devices in today’s many forms.
Published: September 4 2012
This technology dries glassware, controls crucial experiments and more Lab ovens appear in many settings, from basic research to industrial work. Moreover, scientists can choose from a wide range of options. “In the scientific world
Published: June 6 2012
To get enough DNA for processing, such as sequencing the chain of nucleotides, researchers turn to the polymerase chain reaction (PCR). A series of reagents drive this process, and that includes polymerase, buffers, and so on. To make it easier for
Published: June 5 2012
The use of freeze dryers extends from applications in academic labs to zoos. Moreover, this technology contributes to basic research and manufacturing. For example, scientists at a zoo might use a freeze dryer to increase the concentration of a
Published: June 1 2012
When it comes to common technology in a laboratory, centrifuges rise toward the top of the list. If a scientist wants the liquid at the bottom of the tube, but it’s distributed along the sides in droplets, centrifuge it. Need to separate the
Published: May 9 2012
This year marks the 25th anniversary of commercial thermal cyclers for the polymerase chain reaction (PCR). In brief, this technology amplifies segments of DNA. In such a device, PCR tubes go in holes in a thermal block. With everything loaded, the
Published: May 9 2012
A laboratory information management system (LIMS) consists of software with the ability to perform a wide variety of tasks. This technology can help a researcher develop the workflow for a new experiment or high-throughput assay; control the
Published: May 9 2012
The fume hood in your lab might seem ancient, unless you imagine Thomas Edison working in the early 1900s under a fireplace chimney. In the summer, though, Edison’s idea failed to create enough draft as outside temperatures increased.
Published: April 6 2012
The amount of carbon in an organic compound makes up the so-called total organic carbon (TOC), which serves as a crucial metric in a wide range of processes. For instance, TOC can indicate the quality of water or the cleanliness of a
Published: April 6 2012
Balancing the needed increases in selectivity with the desire for generic methods The Greek translation of chromatography— basically “color writing”— fails to reveal the breadth of this technology. The range of
Published: April 6 2012
Lug a tank of gas to an experiment station, break the connection to the old tank, unhook the device that keeps the tank in place, pull out the empty tank and wrestle in a full one, secure the tank in place, attach the regulator and repeat, repeat,
Published: April 6 2012
Electrophoresis relies on a basic process— particles moving in an electric field, more or less. Although known for more than 200 years, this phenomenon still drives fundamental techniques in many laboratories. Despite that long history, this