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Q is for Quality

Volume 5 Issue 4 | May 2010

Cover Story

Despite the vigilance of federal, state and local regulators and of accreditation organizations that evaluate and certify laboratories, the development and maintenance of quality in laboratories are constant concerns.

Sections

Technology

Q is for Quality

Despite the vigilance of federal, state and local regulators and of accreditation organizations that evaluate and certify laboratories, the development and maintenance of quality in laboratories are constant concerns.

Leadership and Staffing

Leading Change

A change in behavior, in attitude or in lifestyle is not easy to achieve, and some seem near impossible. However, the change process can be understood, and change can be implemented more successfully and more reliably by following a few rules.

Technology

The Politics of Stem Cell Research

The NIH recently published its annual report on funding levels for various research, condition, and disease categories. Since the NIH is a government institution, it should come as no surprise that the biggest changes came in areas that have been th

Managing the Coming Data Flood

Lab managers will face an increasing challenge in the next decademanaging a rising tide of data. To realize the full benefit and value of these diverse and voluminous data requires effective data management techniques, institutional arrangements, an

Greening UPS

A new 12-year-rated UPS battery has a smaller carbon footprint but, equally important, will be ready to supply clean power when instruments and other automated test equipment are exposed to utility power problems.

Leadership and Staffing

Science Matters: The Four Characteristics of Successful Networkers

The Four Characteristics of Successful Networkers

Special Reports

Ask the Expert: How to Overcome Challenges with Mass Spectrometry

David Hachey, Ph.D., talks about his role as the director of both the mass spectrometry and proteomics core laboratories at Vanderbilt University.

Evolution of the Lab Centrifuge

The laboratory centrifuge, one of the most important sample preparation instruments in use today, is considered to be one of the most efficient ways to separate samples of different densities.

Lab Product News

AA Spectroscopy: Sensitive, Quantitative Metal Analysis

Atomic absorption (AA) has been known since the 19th century, but it was not until the 1950s, thanks to efforts by Alan Walsh at Australias CSIRO research center, that use of AA spectrometers became routine for metals analysis.

Raman Spectroscopy: Stepchild of Vibrational Spectroscopy Comes of Age

Raman spectroscopy is based on the interaction of visible, near-infrared, or near-ultraviolet light on chemical bonds. When excited with light energy, bonds experience short-lived, higher-energy vibrational states.

Lab Product News

FTIR Spectroscopy: Picking up Steam in Nontraditional Markets

Fourier transform infrared (FTIR) spectroscopy, a subset of infrared (IR) spectroscopy, uses a mathematical algorithm, Fourier transform, to translate raw infrared data into a spectrum.

Chromatography-Mass Spectrometry: Best of Both Worlds

Among the hyphenated mass spectrometry (MS) techniques, gas chromatography-MS (GC-MS) and high-performance liquid chromatography- MS (LC-MS) are the most notable. These methods combine the resolving power of high-resolution chromatography

UV-VIS Spectroscopy: It's all in the Chromophores

Ultraviolet-visible spectroscopy (UVVis), an absorbance-based analytical technique, measures and identifies chemicals that absorb in the contiguous ultraviolet and visible regions of the electromagnetic spectrum. UV wavelengths range

Technology

Perspective On: An Environmental Lab

For Floridas Advanced Environmental Laboratories, success is achieved through strong management support and smart hiring.

Safety Tips

The ABCs of IEQ

Design considerations for laboratory indoor environmental quality. By Vince McLeod

Management

Managing Obsolescence

One of the best approaches for proactively managing obsolescence is to develop and maintain a multiyear capital plan that explicitly designates a specific portion for instrument replacement each year.

A Multi-Vendor Service Model

Multi-vendor service models continue to evolve in order to address changing customer and market needs, such as the increasing need for asset utilization data that is vendor independent.

LabManager

Technology News Water Purification for Ion Chromatography

ICW-3000   Produces a constant and reliable source of ultrapure water for Dionex IC systems Provides a continual flow of ultrapure water to the eluent generator and regenerant lines of the suppressor, reducing carbonate content

Technology News Pocket pH Meter

H-Series miniLab   Features a virtually unbreakable non-glass silicon chip sensor that gives stable readings in seconds Includes a replaceable reference electrode for meter longevity Offers water-resistant operation and e

Lab Product News

Technology News - May 2010

May 2010 Technology News Analytical Single Quadrupole LC/MS 6150B Series Scans at 10,000 amu per second, while maintaining excellent data quality Jet Stream technology uses super-heated sheath gas to focus the ion stream ent

How It Works

Consistent, Stable Incubator and Oven Temperature

Problem: Many experienced lab technicians are aware of the sweet spot in their oven or incubatorthe back right-hand corner of the middle shelf where their experiment or process always comes out right.

Sample Prep for Phospholipid Removal

Problem: Excessive background from endogenous sample matrix components has always been of great concern in bioanalysis, and has become paramount today with the need for decreasing analytical run times. In bio-analytical mass spectrometry, the issue

Measuring Sample Volume and Detecting Precipitates

Problem: Significant time and effort is expended in screening chemical and biological sample libraries. However, no matter how advanced the screening system, the end results are only as good as the quality of the sample in the microplate wells.

Accurate Shearing of Chromosomal DNA

Problem: All contemporary, as well as NextGen and Third Generation sequencing methodologies are dependent on the generation of DNA fragments from initial MegaBase long chromosomal DNA molecules. General requirements are that such fragments have to

Maintaining Sample Viability

Problem: Screw cap tubes are found in the vast majority of laboratories and are commonly used for the long-term storage and cryopreservation of a plethora of sample types. Effectively maintaining sample integrity in these storage environments is of e

LabManager

Technology News CO2 Incubator

Technology News CO2 Incubator Sterisonic MCO-19AIC UVH inCuSaFe™ copper enriched stainless steel interior Single-beam, dual capture infrared CO2 sensor SafeCell UV protection in situ Hydrogen peroxide vapor steril

Technology News CO2 Incubator

DHD AutoFlow NU-5510 Closed Looped HEPA Filtration (CO2 & Air) creates ISO Class 5 Air Quality Microprocessor, non-dispersive, digital solid-state infrared (IR) CO2 Sensor 188L Chamber: Large useable work space with smal

Purchasing Guides

Lab Manager Magazine's Independent Guide to Purchasing A UV/VIS Spectrophotometer

There are many features of a high performance UV/Vis spectrophotometer to consider before making your final purchase. This guide will assist you in short-listing a few models by examining three main selection criteria.

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