October 2013 Technology News

The latest equipment, instrument, and system introductions to the laboratory market.

By

Analytical


Standardized NMR Spectroscopy Platform
AVANCE-IVDr

  • Presently for research use only
  • For NMR clinical research and screening, as well as for IVD-by-NMR research
  • Features high sensitivity and information-rich output at 600 MHz proton-NMR frequency
  • Incorporates advanced hardware, software, automation, spectral libraries and standard operating procedures (SOPs) for high-performance bio-fluid screening and assay validation
  • Optimized for ease-of-use and highest data quality and reliability

Bruker
www.bruker.com


Microspectrometer
MicOS

  • Combines a versatile microscope head directly coupled to a three-gratings imaging spectrometer and a research grade scientific camera
  • Controlled by LabSpec software
  • System’s design makes it compatible over a wide spectral range covering UV-Visible and NIR (200 nm to 1600 nm), allowing the characterization of different types of materials such semiconductor and biological samples

HORIBA Scientific
www.horiba.com/scientific


Long Pulsed LEDs
SpectraLEDs

  • Offer many new wavelengths from deep UV to NIR, with high repetition rates, (0.1Hz to> 2.5kHz) with HORIBA’s DeltaHub electronics
  • Mechanically and optically interchangeable with NanoLED and DeltaDiode sources
  • Feature software controlled pulse duration, and no afterglow, permitting easier interpretation of microsecond lifetimes compared to a xenon flash lamp

HORIBA Scientific
www.horiba.com/scientific


MALS Detector Viscotek
SEC-MALS 20

  • Offers numerous operational features that increase both accuracy and operational ease of use
  • Increased detection at lower angles provides a significant improvement in accuracy compared with other MALS systems, even at high molecular weights
  • New vertical sample flow cell with radial optics allows the use of a variety of mobile phase solvents, without the need for optical readjustment

Malvern Instruments
www.malvern.com


Particle Sizing Instrument
NS500+DLS

  • Gives all the benefit of NTA in high resolution sizing, with DLS extending the lower detection limit to 4 nm
  • DLS software is integrated into the NTA suite, providing easy interchange between NTA and DLS data collection
  • Reports is Z-average diameter, Polydispersity Index (PDI) and Particle Size Distribution (PSD)
  • Easy to use

NanoSight
www.nanosight.com


Replaceable Slits for Spectrometers
Jaz, Torus and QE65 Pro

  • Replaceable slits give users more freedom in spectrometer design and the ability to switch easily from one application to another with the replacement of a few screws
  • Makes possible thousands of applications
  • Allows users to change the spectrometer’s performance directly in the field within minutes, without the need for realignment

Ocean Optics
www.oceanoptics.com


Triple Quadrupole Mass Spectrometer
LCMS-8050

  • Can perform both positive and negative ion analysis in a single run for faster throughput
  • Achieves high sensitivity through a patented ion optics system, a newly designed heated ESI probe and UFsweeper III Collision Cell
  • Offers multiple reaction monitoring (MRM) speeds of 555 ch/sec and maintains spectrum quality, sensitivity and accuracy at scan speeds up to 30,000 μ/sec

Shimadzu
www.ssi.shimadzu.com


Portable NMR Spectrometer
picoSpin 80

  • Allows academic and industrial laboratories to easily collect routine high-resolution nuclear magnetic resonance (NMR) data on molecules in solution
  • Includes a temperature-controlled magnet that does not require liquid cryogens
  • Lightweight, portable design makes it easy to share the instrument across multiple laboratories
  • Also features an easy-to-operate fluid capillary system that does not require NMR tubes or other consumables

Thermo Fisher Scientific
www.thermoscientific.com


Basic lab


Acrylic Flow Meters
ACRX

  • Offered with any one of the interchangeable direct reading scales for air, water, argon, oxygen, carbon dioxide, nitrogen, helium and hydrogen
  • Dual scales display flow rates in both metric and English units, while optional scales can be developed for diverse flow conditions facilitating OEM applications
  • Yellow-colored back plate enhances readability of scales and helps to minimize eye fatigue

Aalborg Instruments
www.aalborg.com


Scroll Vacuum Pump Fossa
FO 0015 A

  • Hermetically sealed, completely dry-compressing vacuum pump is suitable for a wide range of specialist applications
  • When used in conjunction with a turbomolecular vacuum pump, the Fossa provides a completely dry vacuum for use in high vacuum applications
  • Design eliminates contamination or chemical reactions with pump operating fluids
  • Optional gas-ballast valve available for the improved pumping of vapors

Busch
www.busch.co.uk


Undercounter Refrigerators and Freezers
i.Series® and Horizon Series

  • Available in ADA compatible models which are designed to fit under 34” ADA compliant counters
  • Offer excellent chamber temperature uniformity with quick recovery, bacteria-resistant powder coating, and self-closing door with magnetic latch
  • Can be placed under the counter, used free-standing, and stacked
  • i.Series models include a door-mounted i.C³™ user interface with full-color touchscreen

Helmer Scientific
www.helmerinc.com


Rotary Evaporator
RV 8

  • This entry-level model is recommended for all standard evaporation applications
  • Comes equipped with the newly designed HB 10 heating bath, which has enhanced safety features
  • In addition to the vertical glassware, all glassware in the IKA RV 10 range can be used
  • Lift mechanism allows the evaporation flask to be positioned quickly and precisely while using only one hand

IKA
www.ika.com


Oil Evaporator AQUACOUNTER®
EV-2000L

  • Utilizes azeotropic distillation and completely separates water from sample matrices, thus eliminating any side reactions with interfering substances
  • Especially useful for determining moisture in difficult samples such as heavy oils, grease, peanut butter, etc.
  • This CE approved evaporator can be used with the AQUACOUNTER Karl Fischer titrators, or any other manufacturer’s titrators

JM Science
www.jmscience.com


2D Code Reader Tracxer
Code Reader TS201

  • Reads 2D Data-Matrix codes of single 24-, 48- and 96-well format sample storage tubes
  • Able to automatically scan and decode any 2D Data-Matrix code
  • Using the keyboard wedge, high-end decoding engine ensures that the 2D decoding process is highly reliable
  • Requires no software installations and is very easy-to-use
  • Designed to increase user’s productivity

Micronic
www.micronic.com


High Capacity Balances
Explorer Series

  • Traditional external calibration precision models and analytical models with automatic draftshield doors also available
  • New high-capacity models range in capacity and readability from 12kg to 35kg x 0.1g
  • Offer the same intelligent features as the analytical and precision models as well as additional features that enhance high capacity weighing, including 2-D protection and IP54 protection

OHAUS
www.ohaus.com


Temperature Control for Respirometry Applications
Model 210 Heated Circulator & Model 5206M Recirculating Chiller

  • Suited to metabolic studies, biodegradation assessments, forensic evaluations, compost research, toxicity screening studies, and other anaerobic or aerobic research
  • Provide temperature control over a range as broad as -10° to +70°C (14° to 158°F)
  • Model 210 is designed for use with anaerobic respirometers while Model 5206M is recommended for use with aerobic respirometers

PolyScience
www.polyscience.com


Reference Guide for Chemical Resistance
Chemical Compatibility Chart

  • Details the chemical resistance of membranes and matrices used in microplates to a wide range of common laboratory chemicals
  • In the tabulated chart - chemical compatibility data for each microplate material is listed as ‘suitable’, ‘ok for medium term use’ or ‘unsuitable’ thereby offering lab scientists the information to enable selection of just microplates constructed from materials optimized for their application

Porvair Sciences
www.porvair-sciences.com

Product Spotlight

Easy, Peasy Weighing

New Balances Simplify Work in the Lab

User-friendly features are a trend of today’s lab instruments and one that’s exemplified in Sartorius’ release of its latest line of lab balances, Quintix®.

The new balances were developed with help from experienced laboratory professionals and address the “complex menu structure, cryptically described weighing functions and user manuals that had the size of a 300-page book” in older balances, explains Sartorius Quintix product manager Joerg Siedel.

Those problems prevented many users from knowing about and using a lot of the features their balances had, meaning older balances could only be used for simple tasks, Siedel explains.

“That’s why we teamed up with experienced lab users to create a user interface that ensures easy, intuitive operation without having read the manual first,” he says. “The result is our new Quintix.”

All applications are shown as self-explanatory icons on the Quintix touchscreen and can be precisely selected even when the user is wearing lab gloves. The balance also guides users step-by-step through each weighing process to prevent errors.

Another highlight is an internal adjustment function called isoCAL which automatically calibrates and adjusts the balance.

“Users can fully concentrate on their weighing tasks without worrying about calibration or adjustment any longer,” Siedel says. “So they can be sure to get 100 percent reliable and accurate weighing results.”

That means users don’t have to do any maintenance except for cleaning the balance after a day’s work in the lab, an easy task because of the unit’s acetone-resistant surface with clear contours, Siedel adds.

The new balance is available in a choice of 12 models with weighing capacities ranging from 220 g to 5,100 g and readabilities extending from 0.1 mg to 1 g.

For more information, visit http://www.sartorius.com


Cell Culture


Cell Sieve
EASYstrainer

  • Prepares single cells for flow cytometry and to separate individual cells after organ digestion as part of the primary cell extraction process
  • Includes a circumferential mantle surface and handle fitted directly on the sieve to prevent contamination of filter material
  • Suitable for all standard 50 ml tubes and is available in mesh widths 40 µl (green), 70 µl (blue) and 100 µl (yellow)

Greiner Bio-One
www.greinerbioone.com


Chemicals, Kits & Reagents


Toolkit for Nucleosome & Histone Research

  • AMSBIO has added new biotinylated histones and nucleosomes to its expanding range of recombinant nucleosomes, purified nucleosomes and full length histone proteins
  • The new line of biotinylated histone peptides has been developed for enzyme kinetic studies as well as for screening small molecular inhibitors of different histone methyltransferases in drug discovery and HTS applications

AMSBIO
www.amsbio.com


Parallel Synthesis Kit
DrySyn

  • Provides a convenient, low cost solution for chemists wishing to conduct simple synthetic reactions with temperature control and magnetic stirring, but without the complications of reflux or inerting
  • Accommodates a range of standard reaction tubes and vials, of different diameters
  • Can also be upgraded to a parallel reaction station using standard round-bottom flasks

Asynt
www.asynt.com


Reagent Kits for Intracellular Staining
PerFix-Expose and PerFix-nc

  • Minimize sample manipulation for a streamlined workflow that delivers high quality results
  • Developed for use on Beckman Coulter’s Gallios and Navios series flow cytometers and compatible with all Beckman Coulter Life Sciences’ fluorochromes
  • Enable a clear focus on the cytoplasmic and nuclear compartments of the cell

Beckman Coulter
www.beckmancoulter.com


One-step qPCR Kits
iTaq universal SYBR® Green & iTaq universal probes

  • Allows users to obtain highly efficient data in 55 minutes, which includes the reverse transcription reaction, using fast cycling conditions
  • Optimized buffer formulation lets users achieve efficient amplification of challenging templates, cell lysates, and difficult target sequences
  • Provides complete polymerase activation in 30 seconds for greater reaction specificity and superior data

Bio-Rad
www.bio-rad.com


Certified Spiking Solutions® of Bath Salt Metabolites

  • Seven new solutions are 1.0 mg/mL (as free base) in methanol for the primary urinary metabolites of bath salt cathinones, mephedrone, buphedrone, pentedrone, flephedrone, N-ethylcathinone, and 4-methylethcathinone
  • For GC-MS and LC-MS methods that quantify concentrations of synthetic cathinone metabolites, Cerilliant also offers the corresponding deuterium-labeled internal standard to compliment this new line of certified reference solutions

Cerilliant
www.cerilliant.com


High-Fidelity PCR Reagents
Phusion Green DNA Polymerase and Luminaris Color qPCR

  • Part of Thermo Fisher Scientific’s Phusion Fest, an interactive campaign celebrating the importance of PCR in the laboratory
  • Utilize proprietary tracking dyes to speed up the pipetting process
  • By providing a visual confirmation, the mixes are designed to reduce the chance of human error without impacting on downstream steps in the workflow

Thermo Fisher Scientific
www.thermoscientific.com


Lab Automation


UV-Visible-NIR Microspectrophotometer
20/30 Perfect Vision

  • Now available in an automated version
  • Designed to be fully programmable with touchscreen controls so that it can automatically analyze microscopic samples with UV-visible-NIR spectroscopy and microscopy
  • Imaging and spectroscopic analysis of samples can be done by absorbance, reflectance and fluorescence from the deep UV to far into the near infrared

CRAIC
www.microspectra.com


Automated Stainer
Gemini AS

  • Offers improvements in workflow optimization, particularly when multiple protocols are used
  • Features a new, easy-to-use touch screen interface and intuitive software
  • New LED lighting allows the operator a clear view of what is going on inside the staining area
  • Fully compatible with the Thermo Scientific range of coverslippers
  • Allows up to 12 slide racks to be processed at the same time

Thermo Fisher Scientific
www.thermoscientific.com


Life Science


Droplet Digital PCR System
QX200

  • Works with EvaGreen and TaqMan hydrolysis probes (reagents that are used with the instrument) to provide users more flexibility in the design of their digital PCR experiments
  • Provides researchers a tool for the detection of rare mutations, precise measurement of copy number variation, and absolute quantification of gene expression
  • Can be used with Bio-Rad’s 75 Droplet Digital PCR-validated assays

Bio-Rad
www.bio-rad.com


qPCR Probes
PrimeTime Eco & PrimeTime Mini LNA

  • Provide new options for customers performing gene expression and genotyping experiments
  • The Eco Probe is delivered at a normalized yield of 2.5 nmoles, sufficient for approximately 500 reactions
  • PrimeTime Mini LNA Probes enable customers to carry out as few as 100 reactions, allowing preliminary experiments to be performed at a low initial cost

Integrated DNA Technologies
www.idtdna.com


High-Throughput Pipette
Liquidator 96

  • Bench-scale, 96-channel manual pipetting solution provides accuracy without forcing operators to contend with electronic systems or complex computer programming
  • Allows pipetting in 96- and 384-well plates, PCR plates, 8- and 12-channel reservoirs as well as 96-deepwell plates  
  • Can be used by lab technicians at any experience level and still deliver reproducible results

METTLER TOLEDO
www.mt.com


High Content Imaging System
Operetta®

  • Now includes live cell capabilities
  • Improves the ability for scientists researching cancer, stem cells and infectious diseases to perform live cell assays with higher throughput
  • Integrates with advanced informatics solutions like PerkinElmer’s Columbus™ for image storage/analysis and TIBCO® Spotfire® to enable data sharing across multiple experiments

PerkinElmer
www.perkinelmer.com


Single-Use Lab Bioreactor
UniVessel® SU

  • Features a glass bioreactor design with the efficiency and flexibility of single-use systems
  • Includes new single-use sensors for non-invasive measurement of the pH and dissolved oxygen
  • Also includes Connection Boxes for BIOSTAT® controllers and other brands of bioreactor controller
  • Supplied as a completely preassembled and pre-sterilized unit

Sartorius Stedim
www.sartorius.com


UV Crosslinker
Select™ XLE-Series

  • Makes it possible to identify and analyze trace amounts of DNA/RNA with greater sensitivity, accuracy and speed than with conventional analysis
  • Covalently binds nucleic acids to membranes in under 30 seconds
  • Unique true-UV-monitoring circuitry safeguards valuable test results from washouts, even when the tubes age
  • Features five 8-watt tubes and is available in a choice of 254nm, 312nm and 365nm versions

Spectronics
www.spectroline.com


UV Crosslinker
Spectrolinker™ XL-1000

  • “Smart” microprocessor controller and unique, true UV-monitoring circuitry allows users to obtain error-free results faster, safer and more accurately than previously possible
  • Ensures quick, reliable crosslinking by covalently binding nucleic acids to membranes in less than 30 seconds
  • UV-monitoring circuitry guarantees that the set dosage is always delivered, protecting important test results from washout damage

Spectronics
www.spectroline.com


Small-scale Bioproduction Solution

  • Includes a WHEATON® CELLine™ bioreactor flask paired with Irvine Scientific’s BalanCD™ CHO Growth A animal component-free, chemically-defined medium
  • Allows scientists to quickly set up and perform small-scale antibody and protein production while decreasing the cost per milligram produced
  • Provides a highly productive development platform

WHEATON www.wheaton.com
Irvine Scientific www.irvinesci.com

Product Spotlight

A Biopharma Boost

Instrument aims to solve problems in early stages of drug development

Those in the drug development field have a new tool in solving analytical challenges at the preformulation stage of pharmaceutical, and particularly biopharmaceutical, development— Malvern Instrument’s Viscosizer 200. The new automated instrument delivers viscosity and molecular size data on UV-active samples, using volumes of less than 10 μL.

“The Viscosizer 200 really does extend the … toolbox for users within biotech and biopharma as well as providing some interesting applications for those who work in linked industries,” said Malvern’s biopharmaceutical manager Lisa Newey-Keane during the product’s online launch.

Measuring viscosity early in the development of biological formulations is critical in order to reduce the number of candidate failures during subsequent stages of development. The Viscosizer 200 has been engineered to meet early development screening requirements which require automated measurement on extremely low sample volumes, which should ideally be recoverable, as well as operation at high sample concentrations under formulation conditions.

“If preformulation teams are able to identify early on if a new molecule is likely to have a viscosity issue, for example, in the final product, this can save many hundreds of thousands of dollars in development costs,” Newey-Keane said.

The temperature-controlled instrument measures viscosity from 0.9 cP to 120 cP and hydrodynamic radius from 0.2 nm to 100 nm, in samples at concentrations from 0.1 mg/mL to >300 mg/mL. Its integrated carousel autosampler can be configured with a maximum of 45 vial positions.

Malvern’s new system also has a number of other unique features such as UV area imaging and a dual-pass capillary design which enable it to measure viscosity and molecule size more accurately, among other benefits.

For more information, visit http://www.malvern.com/viscosizer200


LIMS & Software


All-in-One Informatics Software
ACD/ChemAnalytical Workbook

  • Included on the ACD/Spectrus Platform
  • Provides an all-in-one experiment, workflow, and data management tool for scientists that use multiple analytical techniques in a problem-solving capacity
  • Links analytical chemistry information with the sample or experiment so that it can be reviewed and re-interrogated to help get answers quickly

ACD/Labs
www.acdlabs.com


Dissolution Workstation Software

  • New version provides better data integration, method change control and instrument monitoring for controlling multiple dissolution systems
  • Allows users to consolidate and maintain electronic data in one location
  • Also lets the user monitor the dissolution apparatus for vibration, environmental impacts and failure investigation assistance when using the optional instrument module, and more

Agilent
www.agilent.com


LIMS
Matrix Gemini

  • Now includes ‘Adhoc data entry’ facility for when users need to capture results for some unexpected or unplanned components of interest that may appear during the testing process
  • Allows the recording of such unplanned results in Matrix without prior definition of the results during test set-up
  • Permits unexpected result entry into any visible region of the grid and more \

Autoscribe
www.autoscribeinformatics.com


Spectroscopy Software
KnowItAll® Informatics System 2013

  • Offers comprehensive solutions for spectral analysis, identification, search, data management, and reporting
  • Includes additions to ATR-IR, IR, Raman, NMR, and MS reference spectral collections • Features enhanced Raman spectrum management • Also includes performance optimizations and workflow simplifications • Gives users advanced GC-MS database building and linking capabilities • Provides support for multiple spectra of the same technique within a single database record

Bio-Rad
www.bio-rad.com


Rheometer/Viscometer Software
RheocalcT

  • Delivers total control of both instrument and test parameters
  • Gives the operator the ability to fully automate viscosity testing from a dedicated PC when using the new DV3T Touch Screen Rheometer and the new DV2T Touch Screen Viscometer
  • User interface presents an enhanced range of choices for test method creation and data gathering/analysis

Brookfield Engineering
www.brookfieldengineering.com


Mobile Apps


qPCR App
MIQE

  • Can be used to validate digital PCR (dPCR) experiments according to the recently published digital MIQE (dMIQE) guidelines (Huggett et al. 2013)
  • Features project-specific checklists and updated references so researchers can stay current with the latest MIQE and dMIQE literature and qPCR symposiums
  • Provides easy exporting so users can save their projects and share them with colleagues

Bio-Rad
www.bio-rad.com


Global Mycotoxin Regulations Tool™

  • Enables instant searchable results for mycotoxin limits by geography and commodity or food type in seconds.
  • Allows food manufacturers and exporters to obtain critical regulatory data without general web searches, saving both time and resources
  • Enables users to search products using commodity and finished product images, simplifying the search process

VICAM
www.vicam.com


Supplies & Consumables


96 Well Microplates with 3D Epoxy Surface

  • Epoxy surface is an excellent platform for covalent binding of proteins, peptides, DNA and oligonucleotides
  • Three-dimensional functional matrix allows the development of covalent binding of nucleophiles to the plate surface without complex coupling chemistry
  • Reduces unspecific binding to a minimum
  • Areas of application include detection methods such as ELISA, ELI-Spot, protein and peptide arrays and DNA binding

Greiner Bio-One www.greinerbioone.com
PolyAn www.poly-an.de


2ml Deep Well Plates

  • Delivers 2.00 ml liquid capacity / well in an automation compatible SLAS / ANSI footprint
  • “Common wall” design provides a full 2ml round well, round bottom well within a 45mm height limit, thus ensuring full compatibility with most plate handling equipment
  • Manufactured under class 10,000 conditions from ultra-pure grade polypropylene

Porvair Sciences
www.porvair-sciences.com


 

Categories: Laboratory Technology

Published In

Leading Change Magazine Issue Cover
Leading Change

Published: October 1, 2013

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Leading Change

Implementing the improvements your lab needs for continued growth and success

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