September 2014 Technology News

The latest equipment, instrument and system introductions to the laboratory market.

By

Analytical

ICP-OES System

5100

  • Enables customers to run samples faster, using less gas and without compromising performance on tough samples
  • Especially suited for labs doing food, environmental, and pharmaceuticals testing as well as mining and industrial applications
  • Requires only one sequential measurement per sample
  • Intuitive ICP Expert software and Dichroic Spectral Combiner technology take the guesswork out of method development

Agilent www.agilent.com 


Glycan Mapping Column

AdvanceBio

  • Designed to deliver fast, high resolution glycan separations
  • Enable laboratories to complete high-resolution glycan mapping separations in less than 10 minutes
  • Available in two UHPLC configurations: 2.7 μm superficially porous particles for high resolution and low backpressure (stable to 600 bar), and 1.8 μm for highest resolution,stable to 1200 bar

Agilent www.agilent.com 


Triple Quadrupole GC-MS/MS

GCMS-TQ8040 with Smart MRM

  • Enables analysis of more than 400 compounds in a single MRM run
  • MRM Optimization Tool automatically determines optimum transitions and collision energies for all compounds in a single sequence, and seamlessly incorporates them into the Smart Database Series for fully automated MRM method development
  • Efficient ion source and collision cell provide low detection limits

Shimadzu www.shimadzu.com 


Triple Quadrupole GC-MS

TSQ 8000 Evo

  • Improves on the features of its predecessor, the TSQ 8000, with new EvoCell technology, demonstrated in company-run experiments to triple selected reaction monitoring (SRM) transition rates without compromising sensitivity
  • Includes Timed-SRM software for optimizing selected reaction monitoring schedules
  • Instrument’s ExtractaBrite ion source is designed for high matrix tolerance to minimize sample preparation and cleaning

Thermo Fisher Scientific www.thermoscientific.com 


Accelerated Chromatographic Isolation

ACI ™

  • New advances convert simple flash purification into a faster and more economical way to isolate pure compounds
  • Traditional purification taking more than 15 minutes is reduced to 5 minutes; a 250 mg scale laboratory scale experiment can now be purified in less than 3 minutes on a 10 g column with an ACI™ enabled Biotage Isolera™ flash purification system

Biotage www.biotage.com 


Integrated HPLC Series

i-Series

  • Improves productivity and promotes an advanced laboratory environment with operation capabilities from the built-in touch panel and a smart device, thereby enabling a PC-free laboratory
  • Consists of the Nexera-i, which supports ultra-high speed analysis, and the Prominence-i, which supports conventional to high-speed analysis
  • Enables control of the instrument from a smart device, such as a smartphone, and via a newly-developed Interactive Communication Mode

Shimadzu www.shimadzu.com 

Product Spotlight

Reimagining UHPLC

New system aims to boost usability, productivity, and performance

Thermo Fisher Scientific recently launched a new ultra high performance liquid chromatography (UHPLC) system that aims to increase laboratory production levels whether it’s used with mass spectrometers or as a standalone system.

The Vanquish UHPLC features a clean design and stands about 25 percent lower than comparable modular stacks for safety and convenience in the laboratory. The instrument itself combines the ruggedness of an integrated system with the flexibility and serviceability of a modular system.

“Rather than making incremental improvements to UHPLC, Thermo Fisher Scientific has designed this system from the ground up,” said Fraser McLeod, vice president and general manager of HPLC at Thermo. “The result is a system that combines advantages in separations performance, sample throughput, ease-of-use, reproducibility and method transfer efficiency.”

Along with the system comes a new family of UHPLC columns–Accucore Vanquish. The new columns feature 1.5 μm solid core particles utilizing Core Enhanced Technology to take advantage of the Vanquish system’s 1500 bar (22,000 psi) maximum pump pressure and flow rate up to 5mL/min for ultra-short diffusion path lengths and highly efficient separations.

The Vanquish also includes a number of other interesting features, such as SmartFlow pumping technology designed for highly reproducible retention times and low baseline noise to enhance detection sensitivity; and an insulated autosampler compartment with new air-to-air cooling, which protects vials from water condensation, even in hot and humid environments.

In addition, there are some cool optional features, such as a handheld tablet that lets users conveniently monitor system status, check runs, and make changes.

For more information, visit www.thermofisher.com/vanquish 

HF System

Q Exactive

  • Designed for faster identification, characterization, quantification, and confirmation in a single, high-confidence analysis
  • Maximum scanning rate increases from 12 Hz to 18 Hz to accelerate productivity
  • Maximum resolution is 240,000 at m/z 200
  • Advanced quadrupole technology optimizes precursor selection and transmission for excellent detection of low-abundance ions in very complex matrices

Thermo Fisher Scientific www.thermoscientific.com 


High Performance Ion Mobility Spectrometer

MA3100

  • Easily integrates with Thermo Scientific™ Orbitrap™ mass spectrometers
  • Enhances mass spectrometry technology by increasing versatility, simplifying complex spectra, and allowing for targeted analysis of gas phase ions that is not always possible by mass spectrometry alone
  • Exchangeable with the current ionization sources of the MS, and when installed it will be detected and controlled by the MS software in forthcoming releases

Excellims www.excellims.com 

Basic Lab

Compact -80°C Storage Systems

BiOS® M and L

  • These high-density automated systems are designed to fit into existing laboratories that require ultra-low-temperature storage of sensitive biological samples
  • Flexible, energy-efficient and scalable systems ensure the viability of 100,000 to over one million long-term samples
  • Samples are held in labware that is both tracked and picked automatically without human intervention, thus avoiding the risk of inadvertent warming and degraded sample integrity

Hamilton Storage Technologies www.hamilton-storage.com 


Double Emulsion System

  • Designed for creating micron-sized emulsion droplets that contain still smaller droplets inside
  • Enables excellent reproducibility and selectivity of droplet size of both outer and inner phases with either oil-in-water-in-oil or water-in-oil-in-water droplets
  • Includes the Mitos P-Pump and the glass Double Emulsion Chip

Dolomite www.dolomite-microfluidics.com 


Fume Hood

Mistral

  • Provides a wide variety of sizes and options to meet users’ laboratory needs
  • Available in bench, high-line, floor-mounted, perchloric, radioisotope, and demonstration versions
  • Meets the industry’s highest safety standards combined with quality, reliability and efficiency from a single platform
  • Features an increased sightline for improved safety, a low profile, ergonomic airfoil for ease of use, and more

Hamilton Scientific www.hamiltonscientific.com 


Centrifugal Evaporator

NEZ-2 Elite

  • Designed to provide final drying of stubborn samples and fast lyophilization of HPLC fractions
  • Able to routinely remove even very high boiling solvents such as DMSO and NMP through the deep vacuum of its high performance scroll pump
  • Internal heating of vapor duct and system components ensures that challenging solvents only collect in the Speed- Trap™ condenser, and not anywhere else

Genevac www.genevac.com 


Stainless Steel Radioisotope Hoods

Protector®

  • Newly redesigned hoods feature fully sealed integral work surfaces with coved interiors to facilitate decontamination
  • Now include two Cord-Keeper slots located on the left and right side of the air foil to allow the sash to close completely when electrical cords from equipment inside the hood are plugged into receptacles located on the corner posts
  • Features an Eco-Foil air foil with Clean-Sweep™ openings

Labconco www.labconco.com 


Ductless Fume Hood

Aura® Elite

  • Includes the latest in microprocessor-based controls, including constant monitoring of fume hood face velocity, gas phase filtration saturation, temperature and humidity monitoring, along with instantaneous filter to chemical application validation
  • Each of these features is displayed and controlled by the EverSafe™ III touchscreen controller, which offers users finger-tip control
  • Monitors fume hood performance constantly while logging the energy consumed

Mystaire www.mystaire.com 


RTD Temperature Data Logger

OM-CP-RFRTDTEMP2000A

  • Features a digital display that shows data in real time along with a battery life indicator and audible and LED alarm indicators
  • Also includes wireless two-way communication, is field upgradeable, and has a cumulative alarm delay feature
  • Especially suited for applications that require high accuracy temperature monitoring

Omega www.omega.com 


Particle Characterization System

CAMSIZER® P4

  • The latest generation of the CAMSIZER product line
  • Offers higher resolution of cameras and lenses as well as faster hardware and software
  • Provides 3-dimensional representation of measurement parameters
  • Includes particle library
  • Features a measuring range from 20 μm to 30 mm

Retsch www.retsch-technology.com 

Product Spotlight

Exchange Flasks With One Hand Behind Your Back

Rotary evaporator boasts user friendly features and wireless control

A new rotary evaporator recently released by KNF Neuberger makes flask exchange much more straightforward. One of the key features of the whisperquiet RC 900 is that it allows a scientist to simply lock the flask into place using just one hand.

“At KNF Lab, we pride ourselves on our strong reputation for producing solid, highperformance equipment for real laboratory situations,” said Jim Findlay, marketing manager of laboratory products at KNF. “The new RC 900 is a perfect example of this, making rotary evaporation more user-friendly than ever before.”

Other new features that make the system easier to use include an adjustable knob that lets users set their optimum flask angle and wireless control of all evaporation functions through a touchscreen and control knob. A cordless heating bath with a pour spout encourages safe emptying without spilling and the system requires only minimal space on the lab bench.

Dr. Alexander Scherer, chair of organic chemistry at the Friedrich-Alexander- Universität Erlangen-Nürnberg, Germany, who has beta-tested the new system in his laboratory, said he was happy with the instrument so far.

“We exposed the RC 900 to real laboratory conditions, such as corrosive and aggressive solvents, and made further suggestions on how to make the system even easier to operate,” Dr. Scherer said. “KNF Lab took these suggestions on board and the result is a high-performance system that features a user-friendly, intuitive touchscreen and automated functions which really make life easier, helping to guarantee highly efficient and safe operation.”

For more information, visit www.knfusa.com 

Ergonomic Footrest

Treston

  • Provides ergonomic support for the feet, legs and back by promoting proper blood-flow while sitting
  • Features a corrugated surface to help prevent slipping
  • A fluted massage roller revitalizes feet while working
  • Footrest is made from polystyrene, and is also available in a black ESD option
  • Dimensions: 19.69” x 14.57” x 3.94”

Sovella USA www.sovella.us 

Cell Culture

iPSC Derived Neural Cells

  • Include normal and Alzheimer’s disease neural progenitor cells, and cerebral cortical neurons
  • Derived using integration-free, fully defined neural induction conditions
  • Capable of generating a spectrum of cortical neurons that are electrically active and have the ability to form functional synapses and circuits in vitro

AMSBIO www.amsbio.com 


Micromanipulator

TransferMan® 4r

  • Combines an intuitive user interface with excellent precision for rapid and simple microinjection
  • Suited to a broad range of applications, including microinjection and manipulation of suspension cells such as oocytes and blastocysts
  • New DualSpeed™ joystick extends the precise and intuitive direct movement control with an additional dynamic speed mode for covering longer distances or speeding up sample processing

Eppendorf www.eppendorfna.com 


High Content Screening Platform

CellInsight CX5

  • Powered by new proprietary HCS Studio™ 2.0 cell analysis software
  • Now with near-IR (infrared) capability, the system is enabled with true five-color spectral illumination, allowing access to a greater range of fluorescent reagents
  • Seven new validated assays were added to the platform, as well as the capability to accept images for analysis in many different formats

Thermo Fisher Scientific www.thermoscientific.com 


hiPSC Reprogramming and hPSC Culture System

L7™

  • Designed for basic stem-cell research, disease modeling, drug development, and regenerative medicine
  • Includes tools to simplify and streamline the stem-cell culturing and reprogramming workflow
  • Supports the generation of reproducible, clinically relevant data as a solid basis for more efficient drug development and accelerated progress in regenerative medicine

Lonza www.lonza.com 

Chemicals, Kits & Reagents

Target Enrichment Kits

SureSelect QXT

  • Next-generation sequencing target enrichment solution produces sample-to-sequencing-ready libraries in just seven hours with only 50 ng of input gDNA
  • Designed to meet the exacting needs of clinical researchers for a fast, easy, same-day sample-to-sequencing workflow
  • Three times faster than existing transposase-based methods and require 30 percent less hands-on time

Agilent www.agilent.com 


High-Purity Laboratory Acids

BAKER INSTRA-ANALYZED™ Plus

  • Optimized for trace metal analysis and designed to meet the needs of those in environmental, food, quality control and other testing applications
  • Feature a selection of widely-used acids specially formulated to enable more accurate trace metal analysis in the very low parts per billion (ppb) range (most from 0.1-1ppb)
  • Produced under strict protocols

Avantor www.avantormaterials.com 


Certified Solutions of NBOMe

Snap-N-Spike ®

  • Include six new certified reference standards of designer psychedelics in the NBOMe (N-methoxybenzyl-substituted) class of phenethylamines
  • New products include 25I-NBOMe HCl, 25C-NBOMe HCl, and 25B-NBOMe HCl and their deuterium-labeled internal standards
  • Supplied in a convenient, quantitative, USDEA and Health Canada (with TK#s) exempt solution

Cerilliant www.cerilliant.com 


UHPLC-MS Solvents & Additives

CHROMASOLV ®

  • Provide high purity for extremely low detection limits under any detection mode– extremely low baseline with minimum impurity peaks such as phthalates and PEG
  • Feature lot-to-lot reproducibility
  • Suitability tested by UHPLC-MS; tightest specification for both positive and negative MS modes
  • Microfiltered (0.1 μm)–no back pressure increase caused by the solvent
  • Liquids are packed in white borosilicate glass containers

Sigma-Aldrich www.sigmaaldrich.com 

Informatics

Pipetting Tracking Software

ArtelWare

  • For use with the MVS® multichannel verification system
  • Enables MVS users to track and manage the performance of their automated liquid handlers over time
  • Aggregates the standardized measurements from the MVS for all of a user’s liquid handlers, providing detailed, actionable performance information and a new level of insight for the management of these critical laboratory tools

Artel www.artel-usa.com 


Liquid Handling Control Software

LHC™ SiLA

  • Allows any proprietary LHC-controlled washer or dispenser to be integrated into a robotic system with SiLA compliance
  • Provides flexibility in instrument component and automated system selection–users choose the best instrument for assay vs. being limited to what can be integrated into current systems
  • Conforms to international standards set forth by the Consortium for Standardization in Lab Automation

BioTek www.biotek.com 


Rheometer Software

Rheo3000 V.2

  • For use with the new family of RST touchscreen rheometers
  • 21 CFR compliant, including controlled user access and data integrity/security
  • Can perform a wide variety of tests including: viscoelastic modulus, yield stress, viscosity vs. shear rate profile, thixotropy calculation, creep behavior, recovery after flow, and temperature sensitivity

Brookfield Engineering www.brookfieldengineering.com 


Microscopy Software

Advanced Fluorescence 4.0

  • Now allows researchers to perform 2D image analysis on multi-channel experiments and fully control the environmental conditions of an experiment
  • Users of widefield systems can now connect to the acquisition station remotely anywhere, at any time
  • Includes a workflow that guides users step by step through the 2D image analysis

Leica www.leica-microsystems.com 


Nanoparticle Tracking Analysis System

Software NTA 3.0

  • Features an improved, easy-to-use interface
  • Makes accessing programs and protocols quick and convenient
  • Incorporates an upgraded high-resolution particle size distribution algorithm, and supports advanced image analysis, particle detection and tracking, as well as providing improved vibration correction
  • Designed for use across the complete NanoSight NTA
  • Included with all new systems shipped, while existing users can download a free upgrade

Malvern www.malvern.com 


Assay Requesting Module

Mosaic 6.0

  • Will be introduced with the release of Mosaic 6.0 in September
  • Provides requestors with a very simple user interface and consolidates requests throughout the user’s organization
  • Generates major time-savings, improves assay platform efficiency and minimizes waste of reagents and consumables
  • Assay preparation details, such as dilution concentrations, delivery form (neat/solution), volumes and plate layout, need only be entered once

Titian Software www.titian.co.uk 

Lab Automation

Automated Gel Electrophoresis Systems

LabChip® GX and GXII Touch™

  • Automate conventional gel electrophoresis, eliminating the need for manual sample preparation
  • Reduce hands-on time and simplify data generation via a user-friendly operator touchscreen
  • The LabChip GX system can enhance genomics research processes by precisely quantifying nucleic acids while the GXII Touch system helps to accelerate the development of biotherapeutic drugs by automating the protein characterization process

PerkinElmer www.perkinelmer.com 


Dual Z Arm for the Cavro® Omni Robot

  • Available with a broad choice of lengths, orientations and options for all three axes
  • Robot is designed to combine precision OEM liquid handling with straightforward integration
  • Option offers two independent pipetting channels in a single housing, doubling the robot’s liquid handling capacity without having to mount an additional arm

Tecan www.tecan.com 


Disposable Transfer Tool

  • Designed for use with proprietary nested LiHa disposable tips, and offers fully automated handling of empty tip trays without the need for a gripper
  • Allows the Freedom EVO’s liquid handling (LiHa) or air LiHa arm to pick up and dispose of empty trays
  • Implementation is designed to be as easy as possible using Freedom EVOware® (v2.6 SP1 onwards)

Tecan www.tecan.com 


Laboratory Automation Solution

Fluent™

  • Designed to offer end-to-end automation of cell-based and biochemical assay protocols, providing exceptional simplicity, productivity and confidence for the automation of experiments
  • Provides high precision, excellent throughput and extended walkaway time, making it easier to get more done, more confidently
  • Available in three sizes–offering deck capacities from 30 to 72 microplates

Tecan www.tecan.com 

Life Science

Proteomics Platform

TripleTOF 6600

  • Includes SWATH Acquisition 2.0, which allows researchers to develop simple, universal assays
  • Brings new power to proteomic data challenges for advanced biomarker discovery and systems biology
  • Enables the quantification of thousands of proteins across large sample sets with a level of data completeness and quantitative accuracy and precision that have only been achievable by “gold-standard,” targeted MRM in the past

AB SCIEX www.absciex.com 


Magnetic Technology

MagSi-Direct

  • Brings the power, simplicity, and convenience of magnetic separation to researchers involved in cell biology, protein chemistry, flow cytometry, diagnostics development and many other fields
  • Provides a convenient and efficient way to attach virtually any biomolecule to nanoscopic paramagnetic beads
  • Particularly suited for exploiting interactions between a biomolecule and its binding partners

AMSBIO www.amsbio.com 


RBM Human Metabolic and Hormone Assays

Bio-Plex Pro™

  • Give users robust performance–validated to meet rigorous analytical standards and manufactured in accordance with GMP guidelines
  • Provide reproducible data–lot-to-lot correlation specification of R2 ≥ 0.9 based on sample testing
  • Supply rapid results–multiplex data in just 3.5 hours through the use of magnetic beads and the fastest assay protocols

Bio-Rad www.bio-rad.com 


Universal Inhibitor-Tolerant SYBR® Green Supermix SsoAdvanced™

  • Allows users to obtain reproducible, optimal-quality qPCR data from the most challenging samples
  • Optimized and validated to tolerate a wider spectrum of PCR inhibitors than other SYBR® Green reagents
  • Includes Bio-Rad’s Sso7d-fusion polymerase, which is engineered for enhanced qPCR performance
  • Compatible with all real-time PCR instruments and functions under any reaction condition

Bio-Rad www.bio-rad.com 


Protein Structure Analysis System

Zetasizer Helix

  • Enables the detailed study of mechanisms of protein aggregation
  • Combines industry-leading Zetasizer dynamic light scattering (DLS) technology, for sizing of proteins and other biomolecules, with Raman spectroscopy
  • Allows measurement of protein size and structure from a single small volume sample, providing unique insight into protein folding, unfolding, aggregation, agglomeration and oligomerization

Malvern www.malvern.com 


Liquid-Based Assays

Zephyr

  • Provides rapid detection and identification of bacteria, viruses and toxins
  • Can help lower cost and hasten development of treatments for harmful and potentially fatal infectious diseases before they spread
  • Includes CANARY® biosensor technology, which enables pathogen detection at sensitivities down to 3 cfu/pfu in less than five minutes

PathSensors www.pathsensors.com 


Slide Incubation System

CytoBrite Duo

  • Dual temperature slide heating instrument for performing FISH hybridization protocols
  • Consists of two independently controlled heating blocks that each hold a 6-slide removable tray
  • Snap heating and cooling of slides eliminates heat damage to cells for more reliable results
  • Slides are sealed with CytoBond removable coverslip sealant, eliminating the need for humidification

SciGene www.scigene.com 

Supplies & Consumables

Container Seals

BioClosure®

  • Now available in silicone and TPE
  • AdvantaPure’s TPE material, AdvantaFlex®, provides an alternative to silicone
  • AdvantaFlex offers lower absorption and adsorption characteristics than silicone and does not contain silicone oils, substances that are undesirable in some biological processes
  • As tubing, AdvantaFlex provides weldability and helps eliminate the need for costly aseptic connectors

AdvantaPure www.advantapure.com 


1 mL Supported Liquid Extraction 48-Well Plates

ISOLUTE® SLE+

  • Enables the extraction of larger sample volumes (1 mL total load volume) than presently possible in the microplate footprint
  • Packed with ISOLUTE SLE+ material; each well containing sufficient ISOLUTE® SLE+ material to efficiently extract 1 mL of aqueous sample
  • Allow users to achieve higher sensitivity, higher throughput and lower detection limits

Biotage www.biotage.com 


Borosilicate Glass Culture Tubes

  • Meet ASTM E890 specification, Type 1 requirements
  • Conform to USP Type 1 standards
  • Are produced in an ISO 9001 certified factory
  • Feature well-rounded bottoms and smooth, fire-polished rims
  • Are chemically inert as well as tissue-cultureand blood-bank-compatible
  • Reduce pH changes and contaminants that can be leached from soda lime glass tubes

Denville Scientific www.denvillescientific.com 


Manual-Inflating Sample Bags

VeriAir Flex®

  • Now available in 1-Liter Tedlar®< and 5-Liter foil
  • Allows an atmospheric grab sample to be collected immediately without any need for preparation, sampling pumps, or other equipment
  • When measuring gas or vapor concentrations with an analytical instrument or different detector tubes, multiple screening tests can be performed onsite with a single VeriAir Flex manual-inflating sample bag

Nextteq www.nextteq.com 

Categories: Laboratory Technology

Published In

Navigating The Post-Sequestration Landscape Magazine Issue Cover
Navigating The Post-Sequestration Landscape

Published: September 11, 2014

Cover Story

Navigating the Post-Sequestration Landscape

Job satisfaction and morale among researchers relying on government grants were body slammed by the sequestration—at least $1.3 trillion in across-the-board funding cuts were mandated by the 2011 Budget Control Act for 2013 through 2021.

Featured Articles

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One of the major benefits of working in the sciences is the ability to have a positive impact on the world through research or the development of new products. That’s certainly the case with working at Redbiotec AG, a biotechnology company located at the Bio-Technopark in Schlieren, near Zürich, Switzerland.