October 2014 Technology News

This month, we highlight companies that will be exhibiting at two upcoming scientific trade shows–the American Association of Pharmaceutical Scientists’ Annual Meeting and Exposition (AAPS 2014) and the Society for Neuroscience’s Annual Meeting (Neuroscience 2014). AAPS 2014 takes place at the San Diego Convention Center from November 2-6 and offers pharmaceutical scientists the opportunity to network with others in their field and check out the latest pharma equipment. Neuroscience 2014 will run November 15-19 in Washington, DC, allowing neuroscientists to present emerging science, learn from experts, forge collaborations with peers, explore new tools and technologies, and advance careers.

By

Remember that the products highlighted in Tech News this month may not be at these particular shows, but their manufacturers will be on hand to answer any questions you may have.

Analytical

Direct Analysis Probe

  • Designed for Advion’s line of expression compact mass spectrometers
  • Creates yet another important tool for chemists that need fast, simple, reliable sample analysis of liquids and solids such as reaction mixtures, food samples, natural products and tablets without the need for sample preparation
  • Delivers essential mass spectral information of compounds in less than one minute

Advion www.advion.com


Autosampler for AA Spectrometers and TOC Analyzers

  • Designed for the AAS family of products – contra®, nova®, and ZEEnit - as well as the TOC Analyzers of the multi N/C® series
  • Offers the same advantages as its predecessor, but has also been optimized in terms of user friendliness and efficiency
  • Allows users to select between a larger selection of possible sample positions for the sample racks

Analytik Jena www.analytik-jena.com


Dual-Mode Purification System

REVELERIS® Prep

  • Allows organic chemists, preparative chromatographers, and other researchers to perform both flash and preparative liquid chromatography using a single unit
  • Researchers can easily switch between flash and preparative chromatography modes with a simple touch of the screen, giving them complete control over the purification process and saving them time
  • Can reduce capital costs for equipment between 40 and 50 percent

Grace https://grace.com


Developers Kit

STS

  • Brings together Ocean Optics’ STS spectrometer, a Raspberry Pi microcomputer, customizable software, and wireless capabilities in a single package for integrating spectral sensing quickly and easily
  • Can be quickly configured for a variety of measurements, cutting set up time and speeding data collection
  • Can be used as a platform to build a compact bench-top spectral absorption system and more

Ocean Optics www.oceanoptics.com


GC Column Set for Chlorinated Pesticides

Zebron™ ZB-CLPesticides-1 and 2

  • Saves time and money for chlorinated pesticide testing commonly performed by environmental and drinking water testing labs, which often need to run up to seven EPA methods on a single instrument
  • Contains two phases with orthogonal selectivities specifically optimized for pesticide analysis, and runs all seven EPA methods
  • Available individually or packaged in a kit

Phenomenex www.phenomenex.com


LC/MS Amino Acid Analysis System

UF-Amino Station
BOOTH 1714

  • Offers simultaneous multicomponent analysis
  • Can analyze 38 amino acids in nine minutes, drastically enhancing laboratory throughput
  • Achieves high-speed analysis utilizing a fast application-specific column and an LCMS-2020 mass spectrometer
  • The LCMS-2020 provides accurate analytical results even under conditions with difficult samples that contain a wide range of impurities
  • Features AmiNavi® software, which simplifies analysis for users

Shimadzu www.ssi.shimadzu.com


Hydrophobic Interaction Column

MAbPac HIC-10
Booth 923 (AAPS)
Booth 2932 (SfN)

  • New column chemistry separates many challenging mAbs, antibody-drug conjugates (ADCs) and proteins
  • Gives users selectivity that is different from other commercial HIC columns
  • Provides the new selectivity with excellent biocompatibility and high recovery
  • Compatible with organic solvent and aqueous mobile phase. It is designed for rugged stability and very low carry-over

Thermo Fisher Scientific www.thermoscientific.com


QTof Mass Spectrometer

Xevo G2-XS
BOOTH 2923

  • Features the new XS Collision Cell
  • Offers uncompromised analytical sensitivity and selectivity in a benchtop QTof mass spectrometer
  • Gives laboratories a dependable option for performing qualitative and quantitative experiments for both known and unknown analytes with a benchtop QTof instrument
  • For targeted quantitative experiments, Tof-MRM mode delivers a 10-fold improvement in signal-to-noise when compared to full scan mode

Waters www.waters.com


Tandem Quadrupole Mass Spectrometer

Xevo TQ-S micro
BOOTH 2923

  • Designed to acquire sensitive, robust and dependable data at accelerated rates of acquisition for numerous analytes at varying concentrations
  • Set to ship in the third quarter of 2014
  • Especially suited for scientists working in food, environmental, pesticides, pharmaceutical bioanalysis and peptide screening
  • Offers six orders of magnitude of linear dynamic range

Waters www.waters.com


Basic Lab

Rheometer Black Pearl

  • Provides a broad range of rheological measurement capabilities including material flow curves and yield stress measurements
  • Capable of measuring viscosities in the range of 1-25,000,000 centipoise
  • In addition to the single-point viscosity profiles, the Black Pearl rheometer also measures temperature ramps (-20°C to 120°C), yield stress, and thixotropic behavior

ATS RheoSystems www.atsrheosystems.com


Laboratory Support Jack

BOCHEM® Lift 240
Booth 1023

  • Features a low voltage electric motor and control system driving a precision support jack made of 18/10 stainless steel, and protected by a PTFE bellows
  • A remote control allows operation with the hood sash closed
  • Maximum height stop can be manually adjusted via an external set screw

BrandTech www.brandtech.com 


Platform for Fluorescence and Electron Microscopy

SECOM

  • May be used to easily and quickly combine light and electron microscopy
  • In its primary configuration, the SECOM platform allows the user to obtain functional color information through fluorescence microscopy and structural information by using the scanning electron microscope
  • “CL marker” technology makes overlay between the fluorescence and electron images fully automated and user independent

DELMIC www.delmic.com 


High Resolution Thermal Camera Kit

FLIR A65sc

  • Produces crisp thermal images of 640 x 512 pixels allowing users to analyze experiments in fine detail
  • Includes highly intuitive FLIR ResearchIR software, which enables researchers to view, record and analyze thermal image data with functions such as time versus temperature plots
  • Comes standard with GigEVision™– a state-of-the-art camera interface developed using the Gigabit Ethernet communication protocol

FLIR Systems www.flir.com 


Back-Illuminated, Deep-Cooled CCD Camera

Syncerity™
Booth 2540

  • Features an NIR-enhanced 2048x70 sensor
  • CCD sensor is designed for companies requiring an affordable OEM camera for VIS-NIR spectroscopy applications
  • Provides a high resolution 14μm pixel size
  • Offers ultralow etaloning and more than 40% quantum efficiency at 1000nm
  • Features peak QE of 84% at 700nm, and 20% at 1050nm

HORIBA www.horiba.com/scientific 


Electronic Pipette Range

VIAFLO II
Booth 516

  • Software now features a full-text, multilingual user interface in English, German, French, Spanish, Japanese and Chinese
  • Easy to use as a single channel manual pipette
  • Integral color screen together with easy-to-navigate touch wheel user interface ensures setup and operation are both simple and fast

INTEGRA www.integra-biosciences.com 


Advanced Microprocessor Controller

Eversafe™ III

  • Touchscreen controller constantly monitors fume hood performance with audible and visible alarms
  • Features large icon display for simple touch control of hood functions
  • Provides variable airflow control with automatic airflow sensor calibration–no service technician required
  • Includes solid state gas detection with three-level sensitivity selection and a temperature and humidity sensor to monitor filter performance

Mystaire www.mystaire.com 


Glassware Cart

  • Made with a durable glacier white, powder-coated tubular steel frame, ergonomic handle, and four-inch diameter nonmarking casters (two with toe locks)
  • Easy to steer and absorb vibration for smooth, quiet trips over rough, uneven floors
  • 19” wide frame fits easily through most doors and narrow corridors
  • Available with 2 large or 4 small vinyl-coated wire baskets

Labconco www.labconco.com 


Laboratory Hoods

Protector®

  • Incorporate a sleek interior with a molded one-piece fiberglass liner
  • Liner is made of specially-formulated, fiberglass-reinforced polyester which offers fire-resistance and easy clean up
  • Eco-Foil™ air foil with Clean-Sweep™ airflow slots allows clean air to continuously flow through the air foil creating a constant, protective barrier of protection from contaminants

Labconco www.labconco.com 


Shaking Dry Bath EchoTherm™

Model SC25XT

  • Fully programmable with 5-program memory and with a temperature range from -20°C to +100°C
  • Includes a variable speed orbital shaker for mixing samples while controlling sample temperature to 1ºC
  • Features a 30-day count down timer with alarm and Auto-off, data logger, and RS232 I/O port for data logging or controlling the units from a computer

Torrey Pines Scientific www.torreypinesscientific.com 


Cryo Reactor

Atlas

  • Offers trouble-free cooling of a range of round bottom flasks
  • Compact unit is just 16 cm (6.3 inches) wide
  • Sophisticated proprietary cooling technology and ‘in reactor’ temperature probe ensure accurate control of temperatures from +10 to -80°C using mains power only; no dry ice, liquid nitrogen, or water circulator required

Syrris http://syrris.com 


Sample Bag Options

Stomacher®

  • Used for food sample blending, straining and storage applications in all lab blenders and homogenizers
  • New closure bag is ideal for sample collection, short term sample storage, as well as sample incubation for pathogen testing and pre-enrichment of food samples
  • Available in 80 and 400 mL formats
  • Features a wire mesh band at the top of each bag for easy opening and tight closure

Seward www.seward.co.uk 


Ultra High-Speed Framing Camera

SIMX

  • Multiple triggering capability allows users to capture frames prior to the trigger, taking the ‘black magic’ out of synchronizing camera and event and allowing users to spend more time on capturing research data rather than setting up their experiments
  • Capable of capturing up to 16 images at 1 billion frames per second
  • Full remote control using Ethernet is standard

Specialised Imaging www.specialised-imaging.com 


Customized Test Weight Set

Essential Weights™

  • Includes either three or four stainless steel test weights in a small, durable carrying case
  • Laboratory professionals no longer need to carry around large cases with unnecessary test weights
  • Specifically tailored to user’s precision weighing equipment, maintaining best practices in routine laboratory calibration

Rice Lake Weighing Systems www.ricelake.com 


Confocal Laser Scanning Microscope

LSM 880 with Airyscan
Booth 250

  • Offers high sensitivity, enhanced resolution in x, y and z, and high image-acquisition speed in one system
  • Airyscan allows users to achieve a 1.7× higher resolution in all spatial dimensions, 140 nm laterally and 400 nm axially
  • The whole imaging process is possible with standard sample preparation and labeling protocols

ZEISS www.zeiss.com


Line Heating Control System

  • Includes an EZ-ZONE RM temperature controller that is extremely flexible and scalable, and allows unparalleled mixing of inputs and outputs to configure control loops, limit loops and monitoring points
  • Features a touchscreen operator interface terminal (OIT)
  • EZ Builder 500 software allows the customer to customize the look and feel of the OIT to match their company’s brand

Watlow www.watlow.com 


Plasma Cleaning System

Evactron ES De-Contaminator™

  • Designed for OEM integration on SEMs/FIBs
  • Starts easily with patent pending “POP” plasma ignition process
  • Performs the same “flowing afterglow™” cleaning that was introduced by XEI with its Evactron Zephyr™ models last year
  • Provides fast carbon cleaning rates of up to 150 Å/min @ 20cm from the plasma source when used with a turbo molecular pump

XEI www.evactron.com 


Laboratory Circulating Cooler

Unichiller 003-MPC

  • Allows users to achieve higher efficiencies and stable pressure and flow rates in comparison to tap water cooling
  • Further reduces water consumption and lowers the operating costs for many applications
  • Features a cooling capacity of 0.28 kW at 15°C
  • Works with natural refrigerants

Huber www.huber-online.com 

Product Spotlight

Optimal Operation

Microscope allows users of all experience levels to acheive best results

Booth 2501

Back in May, at the Control 2014 trade show for quality assurance, the microscopy business group of ZEISS presented its first automated digital microscope. Users will find operation as easy as possible due to the device’s one-of-a-kind operating concept.

This feature makes the new microscope especially suited to industrial environments, where optical inspection is an important part of production-related quality testing. Though parts such as screws, printed circuit boards, and metal elements need to be examined for defects, companies often don’t have the time to inspect these parts, or they may not always have microscopy experts available when needed.

“In this context, the microscope is one of many tools, just like pliers or a wrench. And it must work just as intuitively and reliably,” says Wolf Jockusch, product manager for ZEISS Smartzoom 5.

The microscope is equally suited to conducting failure analyses, such as the close examination of a defective part, as well as to routine inspections, during which the same material sample needs to be repeatedly inspected using the same workflow. Once the quality inspector has placed the sample under the microscope, they no longer have to switch back and forth between the device and the software, but instead can carry out all the necessary steps right on the screen. They can also save this workflow so that it is always available at a later time.

“This makes the analysis reproducible and independent of the user,” Jockusch says. Another cool aspect of the microscope is its Best Image feature, which shows a preview of different illumination options, and the user only needs to select the best one. This means even non-experts can achieve optimal results.

For more information, visit www.zeiss.com

Chemicals, Kits & Reagents

Cell Lysis RT-qPCR Kits

SingleShot
BOOTH 2257 (AAPS)
BOOTH 2823 (SfN)

  • Allow researchers to obtain reverse transcription quantitative PCR (RT-qPCR) data directly from cultured cells without the need for a separate RNA purification step
  • Provide high-quality gene expression results in less than two hours
  • Eliminate the challenges of available column isolation methods for purifying RNA and offer superior reproducibility and accuracy of gene expression results

Bio-Rad www.bio-rad.com 


2C Amine Internal Standards

Certified Spiking Solutions
BOOTH 3418

  • Nine new stable isotope-labeled internal standards of 2C amines are available, including deuterium and 13C labeling
  • Stable-label substitutions of each internal standard correspond to suitable locations for conserving a minimum [M+3] separation from the unlabeled in the major ion fragments used in GC/MS or LC-MS/MS phenethylamine analytical methods • Supplied as USDEA-exempt preparations Cerilliant www.cerilliant.com

CRMs for Environmental Labs

Phenova®

  • This line of ISO/IEC 17025- and ISO Guide 34-compliant standards is for the calibration of analytical equipment and quantitation of analytical measurements for environmental testing
  • Deliver lot-to-lot consistency with the verification of each lot to both internal and independent CRM materials
  • Allows customers to extend their initial calibrations and increase throughput between calibration events

Phenomenex www.phenomenex.com 


Nuclear RIP Kits

Magna™
BOOTH 1923 (AAPS)
BOOTH 1623 (SfN)

  • Facilitate isolation and analysis of RNA molecules associated with chromatin
  • Specially designed to allow the discovery and analysis of both coding and non-coding chromatin-associated RNAs
  • Available for native or cross-linked chromatin for analysis of both high- and low-affinity interactions
  • Compatible with both RT-qPCR or RNA-seq
  • Available in two versions

EMD Millipore www.emdmillipore.com 


ChIP Sequencing Assay Kit

  • Extends the benefits of Porvair’s proprietary Chromatrap® solid state ChIP technology to preparation of purified chromatin for the generation of sequencing libraries
  • Chromatrap is a new quicker, easier and more efficient way of performing ChIP-seq assays
  • This technology now combines the dynamic range of Chromatrap with the downstream analysis power of deep sequencing

Porvair www.porvair-sciences.com 


Informatics

Spectrophotometer Control Software

WinASPECT® PLUS

  • Designed for the SPECORD® PLUS series of spectrophotometers
  • Basic software includes a data handling module for special evaluation of spectra and measurement results, a formula editor, tools for kinetic measurements, layer thickness, and color values
  • Numerous preprogrammed methods for life science applications as well as methods for enzymatic determinations, quantitative water analyses, or brewery analyses are also part of the basic software

Analytik Jena www.analytik-jena.com 


Raman Spectroscopy Software Update

LabSpec 6.3
BOOTH 2540

  • Features a new 3D surface and volume display module
  • Fully compatible with high resolution confocal volume maps acquired with HORIBA’s range of Raman microscopes
  • Provides full control of map rotation, transparency, filtering and slicing, making it easy to view the internal chemical structure of complex heterogeneous samples

HORIBA www.horiba.com/scientific 


Biophysical Characterization Instrument Software Updates

Optim Client v2.1

  • Instruments can probe multiple protein stability-indicating parameters at high speed using ultra-low sample volumes
  • Software updates have been developed to streamline this process, offering faster, more flexible operation and analysis
  • New features simplify and accelerate research workflows, increasing measurement flexibility and allowing users to define custom experimental parameters

Avacta Analytical www.avactaanalytical.com 


Data Analysis Software

Gen5™
BOOTH 2000

  • Customizable pre-programmed protocols now available, designed to estimate relative potency according to the requirements of the USDA APHIS Center for Veterinary Biologics (CVB) guidelines published March 14, 2014
  • CVBSOP0101.01 establishes the criteria that veterinary vaccine producers must use to estimate the relative potency of their test serials prior to submission for licensing through the CVB
  • Protocols addressing both the full dose response and the linear methods for calculation are available for free download from BioTek’s website

BioTek www.biotek.com 


Biotherapeutic Protein Characterization Software

PepFinder
BOOTH 923 (AAPS)
BOOTH 2932 (SfN)

  • Designed to increase the speed, quality and accuracy in comprehensive biotherapeutic protein characterization during drug development and production quality control
  • Streamlines relative and absolute quantitation, and identification of proteins from biological samples using liquid chromatography-mass spectrometry
  • Uses multidimensional dynamic search capabilities to automatically integrate complex data into concise reports

Thermo Fisher Scientific www.thermoscientific.com 


Tools for Variant Annotation and Analysis

VAA Suite

  • Identifies causal variants in next-generation sequencing (NGS) data
  • Helps researchers rapidly pinpoint those variants associated with specific diseases, including cancer and inherited diseases with known genetic causes
  • Adds descriptive annotations to the large, text-based variant call format (VCF) files generated by NGS analysis software
  • Provides advanced filtering and visualization options that enable researchers to sort through data to find those variants most relevant to their studies

Appistry www.appistry.com 


Proteomics Data Analysis Software

Progenesis QI for proteomics version 2.0
BOOTH 2923

  • Enables more rapid and reliable quantification and identification of differentially changing proteins in laboratory samples
  • New features include Pathway Analysis, which aids the biological understanding of observed MS data; QC Metrics, which assesses LC-MS data quality to facilitate exclusion of sub-optimal measurements; and Process Automation, which eliminates the need to program repetitive steps to make analysis even faster

Waters www.waters.com 


Life Science

Magnetic Bead System

SureBeads™
BOOTH 2257 (AAPS)
BOOTH 2823 (SfN)

  • Designed for higher performance immunoprecipitation (IP)
  • Provides researchers with a faster and easier alternative to agarose beads for IP but at a much lower cost than competitive magnetic bead systems
  • Magnetic rack includes a one-piece removable magnet strip, improving sample handling and eliminating repeated centrifugation steps, allowing researchers to achieve results up to six times faster

Bio-Rad www.bio-rad.com 


Real-Time PCR Machine

Genesig® q16

  • Combines a streamlined user experience with the reliability of real-time PCR analysis
  • By utilizing one of the many kits available, the q16 can give reliable, reproducible results in under two hours, compared to days (or even weeks) for more traditional methods
  • Automates post-experiment analysis and so makes qPCR accessible to anyone in a variety of settings
  • Priced at $6,500

Primerdesign www.primerdesign.co.uk 


Two-in-One Transilluminators

Bi-O-Vision™ Series

  • Feature two workstations, producing both 312nm ultraviolet and white light
  • TD-1000R model offers fixed-intensity while the TVD-1000R model offers variableintensity control of either UV or white light
  • Continuously adjustable from 100% down to 50%
  • Enables life science researchers to select medium wavelength ultraviolet or white light illumination to view fluorescent gels or visible blots

Spectroline www.spectroline.com 


Multi-Mode Microplate Reader

Synergy™
BOOTH 2000

  • Offered as an entry-level multi-mode reader to automate UV-Vis absorbance, fluorescence, luminescence and AlphaScreen® AlphaLISA® assays in 6- to 384-well microplates in 2 μL samples with BioTek’s Take3 Micro-Volume plates
  • Unique dual-optics design results in excellent filter-based top and bottom fluorescence, luminescence and monochromator based absorbance measurements for maximum applications versatility
  • Modularity allows upgrading over time

BioTek www.biotek.com 



Automated RNA in situ Hybridization Assay

BOOTH 3003 (LEICA) SfN
BOOTH 3111 (ACD) SfN

  • ACD’s RNAscope® LS ISH assays are now co-marketed with Leica Biosystems’ BOND RX research staining platform
  • Provides researchers with an integrated and fully automated ISH solution
  • RNAscope LS reagent kits and ISH probes are available from ACD while the BOND RX instrument and associated reagents are supplied by

Leica Biosystems Leica www.leicabiosystems.com
Advanced Cell Diagnostics www.acdbio.com


Benchtop Assay Instrument

Countess II FL
BOOTH 1607

  • Features a modular design that broadens the number of applications on a single platform • Includes three channels: brightfield and two optional fluorescence channels
  • Performs assays for cells in suspension, including cell counting, fluorescent protein expression, apoptosis, cell viability and cell cycle assays
  • Can also be configured to use a full range of EVOS light cubes that provide more than 13 fluorescence color options

Life Technologies www.lifetechnologies.com 


Supplies & Consumables

Storage Solution for HPLC Fractions

  • Includes 2ml round deep well microplate and high integrity cap mat seals
  • Microplate provides scientists with a genuine 2ml working volume in a 45mm height plate
  • Flexible, re-usable cap mats prevent evaporation and allow transport and storage of samples in the 2ml plate without the need for expensive heat seals or leaky adhesive-based seals

Porvair Sciences www.porvair-sciences.com 


PCR Plastics for Low-Profile Thermal Cyclers

BOOTH 1023

  • Produced with the newest production technologies, raw materials, and quality testing
  • Feature unique blue alphanumeric coding and cut corner for easy well identification and handling, resulting in more efficient workflow
  • Extra-thin and uniform walls combined with a rigid upper deck results in more optimal heat transfer and sturdiness for use with robotic equipment

BrandTech www.brandtech.com 


384-Well Microplates

CellCarrier Ultra
BOOTH 1254

  • Designed specifically for high content screening (HCS)
  • Improved plate design results in higher quality image data and more robust results from HCS applications
  • These black plates are precisely engineered to have an extremely flat surface for efficient imaging
  • Made using cyclic olefin, a plastic that has glass-like optical properties, to provide a clearer image

PerkinElmer www.perkinelmer.com 


Pipetting Straws

Simplette®

  • Fit a wider variety of variable-volume pipette handsets
  • Provide an accurate and economical sample handling alternative to pipette tips and graduated pipettes
  • Disposable Simplettes are designed specifically to transfer prepared samples from the bottom of a Stomacher® bag without risk of cross contamination
  • Now available with a narrower internal diameter of 3.6-3.7mm, as well as 4.1-4.2mm

Seward www.seward.co.uk 


Categories: Laboratory Technology

Published In

Beyond The Bench Magazine Issue Cover
Beyond The Bench

Published: October 9, 2014

Cover Story

Beyond the Bench

Do you ever feel like you have hit a dead end in your career? Are you too busy attending to staff and their projects to even imagine a life beyond the lab bench?

Featured Articles

Trends in Sample Preparation for Chromatography

Derek Wachtel, scientist in the DMPK department at Ironwood Pharmaceuticals, and Mingliang Bao, PhD, senior scientist at Labstat International ULC, talk to contributing editor Tanuja Koppal, PhD, regarding various issues they face with sample prep in their laboratories. They both stress that sample prep is very important and a necessary step in any analysis and with newer technologies making it easier and faster to accomplish, there should be no reason to ignore or overlook it.