Science and Sustainability

Volume 10 Issue 3 | April 2015

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Cover Story

Featured Articles

Sections

Editor's Buzz

All Things Green

Every April for the past five years, Lab Manager’s cover story has highlighted developments in green laboratory practices.

Business Management

The Procurement Process

Pharmaceutical companies, healthcare providers, research organizations, universities, and government agencies are continuously under pressure to cut costs due to a generalized economic downturn. This pressure has moved the procurement process to the forefront, with managers looking to achieve better business performance through more effective management of categories, suppliers, and teams.1

Leadership and Staffing

Laboratory Technology

Virtual Reality

Communicating the final design of a laboratory to the principal investigators and their research teams can be challenging. 

Lab Health and Safety

Lab Health and Safety Tips

Ask the Expert

Writing the Perfect Chromatography Method

Harm Moes is technical support engineer at SGS in the Netherlands. Mr. Moes has 13 years of experience in analytical instrumentation and held several technical positions with an analytical instrument supplier before joining SGS. At SGS, he provides technical support to the SGS oil, gas, and chemical labs in the Netherlands. That includes implementation and validation of new instrumentation, techniques, and methods, and instruction and training of laboratory personnel.

Product Focus

Titrators: Compliance Based on Best Practices

When the U.S. Food and Drug Administration promulgated its good laboratory practices  (GLPs) for animal toxicology labs in 1979, the regulations were considered a breakthrough in compliance assurance.

Surveys

2015 TOC Analyzer Survey Results

Total Organic Carbon (TOC) analyzers are a mainstay of environmental and quality control chemistry. TOC, a crucial metric in many processes, may arise from a combination of living or dead organisms or chemical contamination. Its measurement can serve as a surrogate for more difficult measurements or a screen for further analysis.

Ask the Expert

Trends in Lab Automation

Dr. Nathaniel Hentz is assistant director of the analytical lab at the Golden LEAF Biomanufacturing Training and Education Center (BTEC), where he develops bioanalytical assays in support of the various biomanufacturing processes taught at BTEC. Since 2008, Dr. Hentz has been responsible for developing and teaching undergraduate and graduate courses, industry short courses, and government (FDA and BARDA) training courses, with a focus on assay development and validation, quality control, and liquid-handling performance.

INSIGHTS

INSIGHTS on Water Testing Laboratories

Water testing laboratories hold a unique position among analytical facilities in their interaction with broadly diverse government and private entities.

Product Focus

Surveys

2015 CO2 Incubator Survey Results

CO2 incubators are designed to copy a cell’s natural environment with a relative humidity of around 95 percent, a temperature of 37°C and a pH of 7.2 to 7.5. They are most common in biology labs performing tissue or cell culture and are used in any process where cells need to be cultured for a few hours or many weeks or where cells need to be expanded or maintained.

Product Focus

Baths and Chillers: All Roads Lead to Efficiency

With chillers, the solution is the same for achieving temperature control, cost-effective cooling protocols, energy savings, and long operating life: mechanical and operational efficiency.

Nitrogen Evaporators: Making Sample Concentration Easier and Greener

When a scientist needs to concentrate a sample that’s in a volatile liquid—like acetone, acetonitrile, or methanol—a nitrogen evaporator can do the job. As a result, scientists use this technology in sample preparation in environmental, polymer science, quality control, and toxicology labs, plus others.

Surveys

2015 ELN Survey Results

Electronic laboratory notebooks (ELNs), one component of a lab’s information infrastructure, help laboratories capture and manage knowledge, streamline data management, protect intellectual property and foster collaboration. Both non-specific/generic ELNs (which compete directly against paper notebooks) and application/task-specific ELNs exist, each with their own fans.

Products in Action

ScrubAir Pipet Washer/Dryer

Water conservation has become a topic of interest in modern lab design. And in keeping up with current market needs, Labconco researched lab water usage and discovered one major sink hole — glass pipet washing.

Surveys

2015 Water Purification Survey Results

Water is the most commonly used laboratory reagent; however, the importance of water quality is often overlooked. Because impurities can be a critical factor in many research experiments, water purity ranks high in importance. There are several types of impurities and contaminants in water such as particulates, organics, inorganics, microorganisms and pyrogens that can adversely affect results.

How it Works

How Pressure-Based Microplate Volume Measurement Works

Problem: In virtually all research processes in which analytes and reagents are mixed in microplates,precise information on the starting volume in each plate well is critical to the accuracy and success ofthe process, as well as the results derived from it. While effective tools for measuring the dispensing of liquid volumes by pipettes have been available for years, accurate volume measurement of what isactually in the plate at a given time has been a challenge.

Laboratory Technology

It's All Under Control

At SLAS2015, the 4th Annual Conference and Exhibition of the Society for Laboratory Automation and Screening, attendees got to check out a particularly versatile multimode microplate reader.

Products in Action

Informatics Infrastructure in the QA/QC Lab

The goal of achieving a truly paperless lab has been discussed for the past 20 years, but it is now, with technology catching up to the discussion, finally materializing. Nowhere is this more evident than in pharmaceutical Quality Assurance/Quality Control (QA/QC) laboratories.