Dr. Donald Sakaguchi, professor of genetics, development and cell biology at Iowa State University, talks to contributing editor Dr. Tanuja Koppal about the time and cost savings generated in his lab due to a recent investment in a high-content screening (HCS) system. While his research group can now set up more experiments to look at different cell types and conditions, they also spend more time carefully designing the experiments and optimizing the conditions and later analyzing the vast amounts of data generated from each experiment.
Combining chromosomes from different organisms started as soon as someone created a hybrid. “In natural breeding,” says geneticist Kulvinder S. Gill of Washington State University in Pullman, “we transfer genes through hybridization—transferring pollen from one plant to another.” He adds, “It can, for example, be pollen from wheat to rye or rye to wheat.”
Cell-based assays have become the go-to technology for pharmaceutical, environmental, and toxicology labs. Cells are far less costly to maintain than test animals and don’t involve the ethical considerations. But the complexity of cell-based assays compared with chemical or biochemical assays presents distinct challenges to laboratory managers.
Pipettes can be found in almost every laboratory and, if you’re looking to buy one, there are many options— manual or electronic, single or multi-channel. Luckily, a few main considerations can help in deciding whether or not to buy the latest pipette technology.
As the most abundant element in the universe, hydrogen might seem easy to come by, except that it’s usually bonded to oxygen in water or bound in organic compounds. Many applications, though, require pure hydrogen.
Freezers and refrigerators are an integral part of any laboratory that requires temperature controlled storage.
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Vacuum pumps are an essential piece of equipment and are used in a wide variety of processes in most laboratories. Over the past 25 years, it has become apparent that vendors have made significant innovative improvements to vacuum pumps, with important developments in high vacuum technology, corrosion resistance, vacuum control, and improvements in the efficiency and ecological impact of vacuum pumps.
Problem: Lab managers frequently need access to a wide variety of equipment that is too expensive to purchase.