When working with certain HPLC solvents, such as acetonitrile / water or methanol / water, a fully dried result can be hard to achieve due to interactions with the dissolved sample—resulting in the formation of a gum or oil. Lyophilization is often the preferred method of sample drying in this case, achieving a high level of dryness with low residual solvent levels. The light, powdery finish of samples prepared in this way enables them to be easily removed and weighed out. However, Lyophilization can be a time-consuming process.
The lower operating temperature (-75°C) of the condenser in the HT Series 3 evaporator, together with automatic solvent draining mid-run, has made Genevac’s proprietary FastLyo™ methodology even more efficient. Using the improved FastLyo™ methodology on an HT Series 3 evaporator—now even the most difficult to handle aqueous / organic solvent mixtures can be removed to produce a clean lyophilized sample with a success rate as high as 96%.
For further information on the HT Series 3 evaporator and technical / applications articles** describing FastLyo™ applications please visit www.evaporatorinfo.com/info25.html or contact Genevac on +44-1473-240000 / +1-845-255-5000 / firstname.lastname@example.org.
Genevac, part of SP Scientific and located in Ipswich, UK, offers a comprehensive portfolio of evaporators to suit almost any solvent removal application, purchasing budget or productivity requirement. SP Scientific is a leading manufacturer of centrifugal evaporators and concentrators, freeze drying / lyophilization, temperature control/thermal management, glassware washers, controlled environments, vial washing, and tray loading machines. The company sells its products under well-known brands including Genevac, VirTis, Hull, FTS Systems, Hotpack, and the recently acquired PennTech. SP Scientific has ISO 9001:2015 registered production facilities in Europe and ISO 9001:2008 registered facilities in the USA.
Evaporators Provide Efficient Lyophilization
State-of-the-art condenser technology enables Genevac's HT Series 3 evaporator, using FastLyo™ methodology, to set a new benchmark for fast and efficient sample lyophilization
| September 26, 2017