Original Broadcast Date: Tuesday January 12, 2016
Characterization techniques based on multi-angle light scattering with chromatography (SEC-MALS) or field-flow fractionation (FFF-MALS) address many of the key analytical challenges in the modern polymer laboratory. This seminar will review light scattering technology, instrumentation, and applications to polymer research.
Select examples will illustrate how a complete light scattering solution based on SEC-MALS facilitates rapid and effective characterization of a wide variety of polymers, including polyacrylamides, acrylic copolymers, nylons, styrenes, and more. Recent advances in commercial applications of high molecular weight and/or branched polymers pose a particular challenge to analytical systems that were designed for simpler polymers. Case studies will be presented to illustrate failures of single-detector chromatography or SEC-MALS, wherein the addition of MALS to FFF made proper analysis possible. The supplemental roles of dynamic light scattering (DLS) and viscometry will also be explored.
- Principles of MALS detection and calculation of polymer molecular size and mass
- Identifying and overcoming shortfalls of conventional GPC/SEC via SEC-MALS
- Leveraging DLS and intrinsic viscosity for enhanced characterization of molecular size
- Calculation of copolymer ratios and molecular weights in-line with SEC
- Advantages of FFF for separation of branched polymers
Andrew Meyer, PhD
Senior Applications Scientist
Wyatt Technology Corporation