Thermo Fisher Scientific has developed a robust ion chromatography (IC) with pulsed amperometric detection-based method for determining iodide and iodate in milk-based infant formula from all major U.S. producers. Application Note 37: Determination of Iodide and Iodate in Soy- and Milk-Based Infant Formulas demonstrates that this method accurately determines the labeled values of all the formulas analyzed and also shows method accuracy with a soy-based infant formula. Performed on a high-pressure IC system, this method has broad linear range (0.005–10 mg/L), high precisions (relative standard deviation <0.3% for retention time and <3% for peak area), and good recoveries.

Iodine is an important micronutrient involved in the regulation of many key biochemical reactions, so its concentration in iodine-fortified foods is often regulated and monitored. Therefore, the U.S. Food and Drug Administration has specified minimum and maximum amounts of iodine that must be present in commercial infant formulas.

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