Thermo Fisher Scientific has developed a robust ion chromatography (IC) with pulsed amperometric detection-based method for determining iodide and iodate in milk-based infant formula from all major U.S. producers. Application Note 37: Determination of Iodide and Iodate in Soy- and Milk-Based Infant Formulas demonstrates that this method accurately determines the labeled values of all the formulas analyzed and also shows method accuracy with a soy-based infant formula. Performed on a high-pressure IC system, this method has broad linear range (0.005–10 mg/L), high precisions (relative standard deviation <0.3% for retention time and <3% for peak area), and good recoveries.

Iodine is an important micronutrient involved in the regulation of many key biochemical reactions, so its concentration in iodine-fortified foods is often regulated and monitored. Therefore, the U.S. Food and Drug Administration has specified minimum and maximum amounts of iodine that must be present in commercial infant formulas.

This application note and many others can be found at www.thermoscientific.com/dionex under the Documents tab.