A wide range of automated liquid handlers offers greater functionality than the simple liquid dispensing offered by the more basic models. Some of the most common functions include nucleic acid preparation, ELISA, assay automation, high-throughput screening and protein crystallography, although many other applications exist.
Multi-function workstations can be used for both clinical and research applications, including automated barcode tracking of samples, reagents, labware, racks and carriers in a variety of automated processes.
Nucleic Acid Preparation / PCR
Automated liquid handlers designed for nucleic acid preparation tend to enable automated RNA, mRNA, gDNA, and plasmid preparation, for example, as well as a wide range of downstream applications.
Automation of ELISA processes is an area of increasing importance to laboratory managers worldwide. A number of automated liquid handlers offer automation of microplatebased chromogenic ELISAs, which can be adapted to meet the changing workflow and throughput requirements of today’s diagnostic laboratory.
Next-generation sequencing liquid handlers are emerging as valuable tools in providing large amounts of genetic information in a single run, increasing throughput and reducing sequencing costs. These liquid handlers are finding application in primary research, health screening, personalized medicine, and single nucleotide polymorphism characterization.
Solid Phase Extraction/Liquid Liquid Extraction
Automated liquid handlers can be used for liquid liquid extraction (partition chromatography) from sample addition to organic phase removal, with high precision, throughput and accuracy. Solid phase extraction (SPE) allows rapid sample preparation and purification for chromatographic or other analyses. SPE can be automated using dedicated automated liquid handlers.