Scientists at Albert Einstein College of Medicine of Yeshiva University and their international collaborators have developed a novel fluorescence microscopy technique that for the first time shows where and when proteins are produced. The technique allows researchers to directly observe individual messenger RNA molecules (mRNAs) as they are translated into proteins in living cells. The technique, carried out in living human cells and fruit flies, should help reveal how irregularities in protein synthesis contribute to developmental abnormalities and human disease processes including those involved in Alzheimer’s disease and other memory-related disorders. The research will be published the March 20 edition of Science.
For its 2014 BioArt Awards, the Federation of American Societies for Experimental Biology (FASEB) awarded top honors for an image produced by postdoctoral fellow Sabriya Stukes and processed by Hillary Guzik in the Albert Einstein College of Medicine's Analytical Imaging Facility.
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