Minimize Hazardous Waste in Your HPLC Workflow

Simultaneous determination of two active ingredients

In recent years, the United States Pharmacopeia (USP) has undertaken a modernization effort to update outdated analytical methodologies in its monographs. This initiative aims to provide updated public standards and reinforce regulatory agencies' efforts to safeguard public health.

A key element of the modernization process is the elimination of hazardous solvents and reagents in the analytical procedure. Currently, the industry uses separate chromatographic methods to analyze each API in pharmaceutical formulations. While effective, this approach can generate large amounts of hazardous waste from organic solvents. To minimize hazardous waste, one solution is to use a single chromatographic method to analyze multiple active materials and their related compounds. 

Download this application note now to learn about a single LC method, specific for analysis of active ingredients and their related compounds, developed to combine three USP monographs for naphazoline HCl and pheniramine maleate ophthalmic and nasal solutions. 

Minimize Hazardous Waste in Your HPLC Workflow

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