As regulatory targets push into the part-per-trillion range, the margin for background interference vanishes. If water supplying blanks, standards, and sample prep carries residual perfluorinated compounds or undetected bacterial by-products, impurities reach the column. The result is signal drift and erroneous peaks that compromise sample data.

This compendium brings together the system requirements needed to protect highly sensitive GC-MS and LC-MS workflows. It details the specific filtration and photo-oxidation steps that extract 62 volatile compounds down to 0.05 ppb, and achieve sub-0.02 ng/L detection limits for ultra-trace PFAS.
Download this compendium to explore:
- Strategies for suppressing baseline noise in purge-and-trap GC-MS
- Isolation parameters for bisphenol A and phthalates in liquid chromatography
- How reverse osmosis, carbon adsorption, and UV photo-oxidation strip strongly bonded PFAS
- Verified performance data tracking PFOA, PFOS, and PFHxS down to sub-ng/L levels



