Equipment for analyzing chemicals in laboratory.
Compendium

How Feed Water Contamination Masks Sub-Nanogram Targets

Trace analysis begins upstream of the instrument—map the purification steps that remove background noise from PFAS and VOC quantification

Written byELGA

As regulatory targets push into the part-per-trillion range, the margin for background interference vanishes. If water supplying blanks, standards, and sample prep carries residual perfluorinated compounds or undetected bacterial by-products, impurities reach the column. The result is signal drift and erroneous peaks that compromise sample data. 

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This compendium brings together the system requirements needed to protect highly sensitive GC-MS and LC-MS workflows. It details the specific filtration and photo-oxidation steps that extract 62 volatile compounds down to 0.05 ppb, and achieve sub-0.02 ng/L detection limits for ultra-trace PFAS.  

Download this compendium to explore:

  • Strategies for suppressing baseline noise in purge-and-trap GC-MS
  • Isolation parameters for bisphenol A and phthalates in liquid chromatography
  • How reverse osmosis, carbon adsorption, and UV photo-oxidation strip strongly bonded PFAS
  • Verified performance data tracking PFOA, PFOS, and PFHxS down to sub-ng/L levels 

Sponsor

  • Elga Veolia

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