May 2012 Technology News

Diode Array Detector for LC
1200 Infinity Series

• Delivers 30 times wider linear UV-range and up to 30 times higher sensitivity than previous detectors
• Acquires all sample information in a single run
• Extends the upper linearity level from two to typically six absorbance units

Agilent
www.agilent.com

Product Spotlight

Double the Chromatography, Double the Information Content System combines SFC and UHLPC for added speed

The first commercial instrument that performs both supercritical fluid chromatography and ultra high-performance liquid chromatography recently hit the market with Agilent Technologies’ 1260 Infinity Hybrid SFC/UHPLC system.

Agilent liquid phase separations product manager Martin Vollmer said customers have been loving the new system so far.

“Customers are excited that they—for the first time—can run LC and SFC on a single instrument and basically double their information content without changing systems,” Mr. Vollmer said. “They also love the unique flexibility and modularity; if they buy a Hybrid system they are prepared for future changes.”

Users are also pleased that the system easily converts to either a standalone SFC or UHPLC or can integrate modules into pre-existing systems, he added.

“They [customers] like that they can easily expand their detection capabilities with an additional detector [and] integrate full-blown method development and column and solvent screening,” Mr. Vollmer said, adding the system’s 600 bar capability is another thing users are pleased with.

Mr. Vollmer said the Infinity is especially suited to the pharmaceutical industry but is also useful for food or environmental applications since everything can be done on one system, meaning speedier production over normal phase methods.

“A Hybrid system provides much more confidence for the user who can still run those validated methods but at the same time, on the same instrument, he can peer-to-peer develop faster methods with SFC,” he said.

He added the system can also be built up using pre-existing 1100, 1200 and 1260 Agilent modules, meaning customers can save a lot of money.

For more information, visit www.agilent.com/chem/infinity-sfc

UV/Visible Spectrophotometer
Jenway 6850

• Features a variable spectral bandwidth of 5nm down to 0.5nm
• Includes highly stable optics
• Provides accuracy and stability over long periods of time
• Ensures improved peak resolution
• Integrated user interface provides full control of the instrument

Bibby Scientific
www.bibby-scientific.com

Mass Spectrometry Source
DART®-OS

• Utilizes the simple OpenSpot® sample cards for sampling, transfer to the lab, and analysis
• Eliminates need to dissolve samples in solvents and transfer to and from sample containers
• Minimizes sample contamination

IonSense
www.ionsense.com

NIR Light Source
Vivo

• A compact, tungsten halogen light source for VIS-NIR spectroscopy across the 360-2000 nm range
• Delivers powerful output for reflection and other measurements
• Cooling fan reduces the risk of overheating the sample
• Enables shorter spectrometer integration times than conventional methods

Ocean Optics
www.oceanoptics.com

Automated Analyzer
AA1

• Employs new technology based on segmented flow analysis for rapid, accurate, precise analysis of parameters
• Performs up to 120 tests per hour
• Features compact design and is able to run unattended
• Includes minimal flow paths and the ability to add samples at any time during a run

SEAL Analytical
www.seal-analytical.com

Sample Conductivity and pH Accessory for IC
Dionex AS-AP

• Streamlines IC workflows by automating conductivity and pH measurements before injecting samples onto an IC system
• Allows users to confirm the integrity of their samples in advance
• Accessory also automates other pertinent parts of the measurement process

Thermo Fisher Scientific
www.thermoscientific.com

Pulsed Discharge Detector
VICI D-3-1-HP

• Designed for plug-and-play installation on Agilent GCs
• Optimized for trace level work in the helium photoionization mode
• Utilizes the electronics and power supply of the host GC
• Suitable for use with columns from 50 micron capillaries to 1/8 packed
• Non-radioactive, non-destructive, highly sensitive and universal

Valco Instruments
www.vici.com

Basic Lab

Ductless Chemical Workstations

AC600 Series

• Smaller and more mobile than a traditional or ductless fume hood
• Offer gas phase bonded carbon filtration, real-time gas detection and constant airflow control and monitoring
• Can be configured with multiple carbon and HEPA filters
• Features the AirSafe™ automatic safety controller

AirClean Systems
www.aircleansystems.com

Film Isolator
Purair Flex

• Provides more working volume than comparable products
• Double O-ring design allows users to quickly and easily change gloves
• Easy to setup up and provides increased stability
• Safety options include HEPA filter availability, bag-in / bag-out port, and optional nitrogen purge inlet connections

Air Science USA
www.airscience.com

Hotplate Stirrer
Asynt

• Incorporates two independent control circuits, so that the set temperature values are held constant in the event of one circuit malfunctioning
• Includes an expanded range of safety features
• Hermetically sealed design protects the motor assembly from spillages

Asynt
www.asynt.com

Magnetic Mini Stirrer
Stuart SM5

• Stirs volumes up to 1 liter and offers a choice of three stylish fascia designs
• Provides stirring speeds of 350 to 2,000 rpm
• Constructed from polypropylene with a chemically resistant polycarbonate top
• Casing incorporates silver-based BioCote® antimicrobial protection

Bibby Scientific
www.bibby-scientific.com

Product Spotlight

Getting the Full Spectrum of Assay-Boosting Features New microplate tech simplifies LAB applications

BMG LABTECH’s SPECTROstar Nano microplate reader is the only instrument of its kind that can capture a full UV-Visible spectrum (220 to 1000 nm) in less than 1 sec/well. The instrument also allows users to perform assays quickly and easily in both microplates or by the built-in cuvette port.

That means users don’t need to use a separate cuvette absorbance reader with a spectrometer and then adapt the assay to a microplate reader, said Ph.D. and BMG’s international marketing director Edward Dell.

“[With older instruments] only one or two different wavelengths could be used in the microplate format because fast, full spectrum analysis was not possible on a microplate reader,” Mr. Dell explained. “Now with the SPECTROstar Nano, assay development and throughput can be done on the same instrument without having to limit the assays to certain wavelengths, and thus compromising data.”

He added the system has all of the standard absorbance applications programmed as quick start app-style buttons, including DNA, RNA, protein, NADH, ELISA, BCA, and cell growth. The reader is particularly suited to multi-wavelength, enzyme kinetic assays and assays where the peak absorbance wavelength shifts, Mr. Dell said.

“However, full spectrum analysis will greatly improve all absorbance assays,” he said, adding that the instrument got a good response from attendees at ARABLAB 2012 in March

“Many of the visitors there were starting new labs and/or were looking to purchase a microplate reader for the first time,” he said. “These visitors were very intrigued with this new technology and how it could improve their assays in their laboratories.”

For more information, visit www.bmglabtech.com

Rinse Station
TerraSpray™

• Cleans all styles of vessels and carboys up to 50 gallons (200 liters)
• Connects directly to water inlet and drain—no electricity needed
• Countertop or floor models available
• Crafted of a roto-molded polyethylene top panel and fabricated polyethylene base and legs

Cole-Parmer
www.bibby-scientific.com

Rolling Cabinet for Centrifuges

• Allows 5804/5804 R or 5810/5810 R centrifuges to be easily stored or moved
• Constructed of powder-coated steel for strength and high chemical resistance
• Includes large drawer with slip-resistant lining for accessory storage
• Features two lockable castors and sturdy build for safety

Eppendorf North America
www.eppendorfna.com

Product Spotlight

Take Control in the Lab Peristaltic pump lasts longer and is easier to use

In response to customer demand for independent-channel control in a peristaltic pump, IDEX Health & Science recently released its new Ismatec® Reglo ICC for laboratory use.

“Virtually all our customers—laboratory users, distributors, and instrument manufacturers—clearly asked for independent channel control,” said Ismatec product manager, George Bednar. “Prior to this time, no other pump maker had been willing to make the substantial engineering commitment required to bring the ICC to market.”

The pump also offers one-, two-, or three-channel configurations and features a re-engineered, long-life drive mechanism, a space-efficient footprint, and digital software control from the keypad or computer.

Mr. Bednar added that customers have shown high interest in the pump so far and the company expects an interim ramp-up period to build sufficient shelf stock for rapid delivery.

However, that doesn’t mean customers won’t be able to get a good deal on the instrument

“Through September 1st, we’re offering the ICC at a one-time, introductory price equal to our standard Reglo digital pump—so you can essentially buy three pumps for the price of one,” he said.

For medical applications, Mr. Bednar explained the pump is best suited to ADME Tox applications, dialysis, electrophysiology, organ and tissue perfusion, and physiology. The pump is also suited to food and beverage production, agriculture and industry, and more.

“Because of the low-flow accuracy of Ismatec pumps, we’re seeing the greatest interest from laboratories that need to dispense discreet buffers and reagents for automated or sequential analysis such as batch-fed fermentations, liquid-phase reactor systems, or controlled feeding distribution,” he said.

For more information, visit www.idex-hs.com

Laboratory Vacuum System
VACUSAFE

• Conveniently and safely disposes of almost any liquid waste
• Includes a liquid waste level sensor to prevent overfilling of the bottle
• Also features two hydrophobic filters that block potentially dangerous aerosols from entering the lab workspace
• Comes with a wide range of VACUBOY adapters

INTEGRA Biosciences
www.integra-biosciences.com

Industrial Gas Standards Generator
Span Pac

• Produces precise, accurate calibration gas mixtures with concentration traceable to NIST
• Dynamically blends concentrations from low ppb to over 1000 ppm
• Requires no interstage mixtures
• Safe and easy to use with single and dual models available

KIN-TEK Laboratories
www.kin-tek.com

Basic Chemistry Workstation
FE-2620

• Handles aromatic hydrocarbons and other general solvents
• Features adjustable airflow control up to 120fpm
• Light weight, economical, and compact
• Optional spill tray and fluorescent light available

Mystaire Misonix
www.mystaire.com

Precision Fluidized Bath
FFB-8 Series

• Offers a wide operating range of 50 to 700°C (122-1292°F)
• Also includes PID temperature control and a built-in dust extraction and collection system
• Provides a safe, essentially isothermal environment with a high rate of heat transfer

Omega Engineering
www.omega.com

Heat Sealer
MiniSeal Plus

• Ensures high integrity sealing of deep well or even irregularly-shaped microplates
• Only requires plugging into a single electrical outlet to operate
• Does not need a compressed air supply to operate
• Offers adjustable temperature heat-sealing from 50C up to 200C

Porvair Sciences
www.porvair-sciences.com

Fluorescence Illumination System
Lumen 200S

• Includes a wide variety of control options
• Features a 2,000 hour life, 200 Watt metal arc lamp with a stabilized DC power supply
• Six-position, adjustable aperture/intensity knob to protect samples from photobleaching
• Provides quiet operation

Prior Scientific
www.prior.com

Vibratory Sieve Shaker
AS 450 basic

• Sieves large quantities up to 15 kg
• Accepts sieve diameters up to 450 mm and covers a measuring range from 25 µm to 125 mm
• Allows time and amplitude to be digitally set
• Offers efficient electromagnetic drive with 3D movement

Retsch
www.retsch-us.com

Ultraviolet Viewing Systems
CC-80 and CC-81

• Provide “no-wait” photo-documentation of research findings
• Eight “snap-on” camera adapters available
• Offer users a choice from a wide range of Spectroline UV lamps
• Feature built-in white light sources that provide visible illumination for easy preparation of samples

Spectroline
www.spectroline.com

CHEMICALS, KITS & REAGENTS

Aldosterone Solution for LC-MS-MS Testing
Certified Spiking Solution

• Available at a concentration of 100 µg/mL in acetonitrile
• Suitable for use as a critical starting material in preparation of linearity standards, calibrators, or controls for aldosterone testing by LC-MS-MS
• Eliminates variability

Cerilliant
www.cerilliant.com

Surface Coating Agent
Pico-Glide

• Suitable for treatment of both glass and PDMS microfluidic channels
• Ensures improved droplet performance and stability
• Available in 5ml, 10ml and 25ml; easy to use
• Can be used together with Dolomite’s range of Droplet Junction Chips

Dolomite
www.dolomite-microfluidics.com

Water Pretreatment Kits
LabStrong

• Compatible with various water purification systems including Fi-Streem Stills
• Allow for customization based on inlet water quality and existing purification system plumbing
• Single and dual cartridge holder versions available

LabStrong
www.labstrong.com

Reference Substance
SmartCal

• Designed to verify and document moisture analyzer performance with a simple 10-minute test
• Easier and simpler alternative to the traditional method for testing moisture analyzers
• Ensures that instrument performance is in accordance with specifications

METTLER TOLEDO
www.mt.com

B-Hydroxybutyrate Kit for Beckman Synchron® Analyzers
LiquiColo

• Comes with two bottles configured to fit Beckman Coulter analyzers
• Each bottle contains the ß-hydroxybutyrate enzyme (R1) and the ß-hydroxybutyrate catalyst (R2)
• Includes a 1.00 mmol/L standard
• One bottle yields 90 tests, for a total of 180 tests per kit

Stanbio Laboratory
www.stanbio.com

LIFE SCIENCE

Ready-to-Use Lentiviral Particles
AMSBIO

• Allow direct visualization of organelles or structures in cells without manipulation
• An easy way to provide long term labels on many cellular structures
• Don’t need transfection reagents
• Can target 3 different structures in the same experiment

AMSBIO
www.amsbio.com

DNA Sample Concentrator
miVac DNA

• Simple “select & set” single control knob enables even new users to obtain excellent results the first time and every time
• Capable of removing low volumes of water and organic solvents from a variety of sample formats
• Operates without a motor; includes special operational modes

Genevac
www.genevac.com

Syringe for Neuroscience Research
Neuros

• Available with ultrafine 30-, 32- or 33-gauge needles that accurately dispense 50 nL to 100 µL
• Adjustable needle sleeve maintains rigidity and ensures a targeted injection path
• Enable precision animal brain injections with minimal tissue damage and reduced variability

Hamilton Company
www.hamiltoncompany.com

ISCA +SNP (4x180k) Microarray
CytoSure

• Combines array comparative genomic hybridization (aCGH) probes with fully validated single nucleotide polymorphism (SNP) content
• Allows the accurate and cost-effective detection of copy number changes and loss of heterozygosity (LOH) using a single array
• Includes enhanced SNP coverage for high-resolution LOH detection

Oxford Gene Technology
www.ogt.co.uk

Infrared Antibody Arrays
Proteome Profiler 96

• Use an ELISA-based format for the high-throughput analysis of protein kinase phosphorylation
• Detect the relative phosphorylation of multiple kinases in a single sample of cell lysate
• Features a three-hour assay time and is amenable to high-throughput

R&D Systems
www.RnDSystems.com

Vitamin D Depleted Diluent
SeraCon

• Instrumental in the development of accurate Vitamin D assays
• Derived entirely from human plasma
• Does not contain any equine or synthetic plasma
• A good fit for in vitro diagnostics manufacturers
• Available in large lots of up to 200 liters

SeraCare
www.seracare.com

Scanning Imaging Cytometer
Acumen® eX3

• Able to analyze over 300,000 wells a day
• Provides a resolution equivalent to a 20x microscope objective
• Enables users to assess multiple parameters in a single assay
• Flexible and simple to use
• Significantly reduces the time to results

TTP Labtech
www.ttplabtech.com

Monoclonal Antibodies to Clostridia GDH
ViroStat

• Adding GDH detection with toxin detection significantly improves assay specificity
• Three new monoclonal antibodies available
• Represent a new set of tools for rapid detection development
• Validated by ELISA

ViroStat
www.virostat-inc.com

2D Barcode Reader
PluraScan

• Designed to capture data stored as 2D data matrix barcodes on cryogenic storage vials
• Saves time while reducing data entry errors
• Comes with an out-of-the box software decoder system
• Capable of scanning up to 100 samples simultaneously Wheaton www

Wheaton
www.cryofeed.com

lims & software

Chemical Process Analytical Deployment Software
Symbion-EX V. 2.5

• Provides a secure environment for the locked down deployment of analytical instruments
• Can allow the control and coordination of multiple analytical systems within a given unit operation
• Now includes Oracle™ products as the standard database platform underlying Symbion

Symbion Systems
www.gosymbion.com

NIR Software Driver
Thermo Scientific TruProcess

• Enables the TruProcess instrument to be interfaced to the Symbion-DX and RX Software Suites as well the Thermo Scientific GRAMS-RT Suite
• Expands chemical and process development abilities as well as on-line process control within a regulated environment
• Software can also allow analyzers to operate as autonomous systems

Symbion Systems
www.gosymbion.com

supplies & consumables

Microvolume Cuvette
BioDrop

• Provides a robust, accurate and affordable approach to low volume spectroscopy
• Simple optical layout provides very high energy throughput
• Ensures that highly accurate measurements can be made over a wide dynamic range
• Only requires one path length for most experiments

BioDrop
www.biodrop.co.uk

Bleach Towelettes for Centrifuges and Glucometers
HYPE-WIPE® and MINI HYPE-WIPE

• Saturated with the CDC/OSHA/NCCLS recommended 1:10 dilution of sodium hypochlorite
• Stabilized for an extended shelf life
• Also contain detergent so that they clean and disinfect in one step
• Expiration date is stamped on every pouch; available in two sizes

Current Technologies
www.currtechinc.com

Aluminum 96-Well Microplate System

• Suited for use with volatile solvents and testing that requires uniform heating and cooling of samples
• Designed to secure 0.5mL, 1.0mL, 1.5mL and 2.0mL conical and flat bottom glass vials
• Compatible with all liquid handling systems

J.G. Finneran
www.jgfinneran.com

Tissue Culture Flasks
TPP

• Offer a uniform, flat growth surface and allow complete interior access
• Reduce media and labware costs
• Enable consistent and reproducible experimental results
• Available in 25, 75, 150 and 300 cm2 volumes
• Filter caps incorporate a 0.22 µ hydrophobic PTFE membrane

MIDSCI
www.midsci.com

UHPLC Column Protection for Widepore Columns
SecurityGuard™ ULTRA

• Protects widepore (=200 Å) UHPLC columns
• Extends the lifetime of columns packed with sub-2 micron fully porous or core-shell particles
• Shields against the damaging effects of chemical contaminants and microparticulates

Phenomenex
www.phenomenex.com

Polypropylene Flip Cap Centrifuge Tubes

• Designed for easy one-handed operation
• Available in a range of standard sizes
• Compatible with almost all centrifuge rotors
• Affordably priced and can be spun up to 9400G
• Will withstand repeated autoclaving at 121C or long term storage at -80C

Porvair Sciences
www.epigeneticsexpress.com

MS Syringes
Diamond

• One hundred times more sensitive than a conventional syringe
• Ensures the lowest possible syringe carryover
• Excellent cleanability delivers improved sensitivity for MS users
• Three ultra-smooth needles available
• Can reduce non-specific interaction and increase sample recovery

SGE Analytical Science
www.sge.com

Water Sampling Bottles
Sterilin

• Designed for either chlorinated or non-chlorinated water sampling
• Available in square and rectangular designs
• Reduce the risk of contamination as well as bottle-neck damage
• Tamper-evident seals also reduce the need for re-testing
• Manufactured from polyethylene terephthalate (PET)

Thermo Fisher Scientific
www.thermoscientific.com

Single-Use Syringe Filters
Titan3 and Target2

• Enhance sample preparation workflow by accommodating greater burst pressures and providing exceptional flow-through characteristics
• Offer improved reliability and performance
• Available in a wide range of filtration membrane types and porosities

Thermo Fisher Scientific
www.thermoscientific.com