Lab Manager | Run Your Lab Like a Business

Lab Product

HPLC Systems

Top 8 Signs That You Should Service or Replace Your HPLC System

Top 8 Signs That You Should Service or Replace Your HPLC System

New applications require more modern, speedy, and sensitive methods.
When any piece of hardware repeatedly suffers from the same malfunction.
If one is unable to obtain spare parts, then its replacement should be considered.
When any piece of hardware is beyond economical repair.
If the software is too inflexible to meet current requirements, then an alternative software package should be considered.
If an item of hardware of the HPLC system is not sufficiently flexible to cope with current or future requirements, then an alternative item of hardware should be considered.
If it is not possible to obtain customer support for that item.
An organization is standardizing the HPLC systems they use.

Top 6 Questions That You Should Ask When Buying an HPLC Columns

How flexible is the system? Ask about whether the system can be optimized to meet your laboratory requirements.
What tubes, vessels, vials can it accommodate? Can components (such as additional detectors, valves, etc.) be upgraded in the future?
Is the software easy to use and operate? Can a demo version be put in place to get a feel for how the software functions for your laboratory’s workflow?
How is the system (not just components) qualified during installation as to meeting manufacturer performance expectations?
Who provides the support and service for the product? Is it the manufacturer or a third party service group? If it is a third party service group, are they factory-trained?
Finally, ask about cost of the purchase; not just the price of the product being installed but the total cost of ownership, which includes price, service expectations, warranty, etc.

Recently Released HPLC Systems


  • Includes new design improvements such as updated electronics and user interface
  • Updated system maintains key Alliance performance specifications and control algorithms to ensure that catalysts can seamlessly replicate their existing methods
  • Changes will not affect established, validated HPLC methods
  • Suited to help scientists enhance their HPLC methodologies through the use of Waters eXtended Performance [XP] 2.5 μm columns


Merit HPLC Range

  • Easy-to-use, low cost system reduces the time needed for software familiarization
  • Offers performance of the highest specification
  • The fully PC controlled isocratic and binary systems with the new Merit software provide automatic integration of chromatograph peaks without operator intervention
  • Suited for screening, quality assurance, method development, teaching and use by novices

Cecil Instruments

1290 Infinity Binary LC System

  • Emulates other HPLC and UPLC systems, connects to all Agilent and many non-Agilent software
  • Provides high performance and flexibility
  • Features HPLC-like service costs—UHPLC productivity
  • Boasts an infinite power range that combines ultra high pressure up to 1200 bar and high flow rates up to 5 mL/min
  • Quaternary version also available


Dionex UltiMate 3000 System

  • Provides increased application flexibility with binary and quaternary solvent delivery for HPLC and UHPLC
  • Options from 9,000 psi standard to 15,000 psi RSLC available
  • Gives users excellent analytical reproducibility with ultrafast sampling speeds and extremely low carryover
  • Also provides maximum separation efficiency and retention time precision with column temperature control

Thermo Fisher Scientific

HPLC System Manufacturers


Beckman Coulter


Buck Scientific

Cecil Instruments



Hitachi High Technologies





SSI LabAlliance

Thermo Fisher Scientific