Like great athletes and musicians, cells employed in cell-based assays or as expression systems for biopharmaceutical production are not born, but made. Cell lines that perform specifically and predictably arise from a population of cells that have undergone one or more genetic transformations (transfection) and are subsequently selected for desirable properties such as viability, protein or virus production; high culture density; or binding to drugs or antigens.
Laboratory shakers come in a variety of configurations, including orbital, horizontal, incubator, tumbling, roller, overhead, rotator, and the subject of this article, rocking shakers. Within these categories, numerousvariables are possible: physical size and sample capacity, speed adjustment, shaking direction, sample pitch, direct temperature control through heating or cooling coils, and environment control through enclosures or use within incubators.
Microplate readers are commonly used in biological research for assay development (39.4%), measurement of biomolecule concentration (34.5%), cell biology (25%), biomarker research (24.0%), and DNA quantification (20% of survey respondents). In addition, microplate readers find use in disease study, IVF, proteomics, PCR setup, and stem cell research. With multiple read modes available and numerous accessories, choosing a microplate reader that meets your current and future needs can prove a daunting task.
If a product or industry involves particles, and most do, someone analyzes the size of those particles.
Refractometer manufacturers quote accuracy and reproducibility to the fourth, fifth, and sometimes even the sixth decimal places. A good manufacturer will only advertise this level of accuracy after carefully running standards.
Laboratory ovens are common instruments in most laboratories and are used across most scientific disciplines. Lab ovens are most commonly less than 12 cu.ft. in volume, although a great variety of sizes are available in benchtop, stackable, and floor-standing models. Over 25% of survey respondents reported using larger ovens in their labs. While lab ovens are most commonly used for heating and drying (75.6% of respondents), they find a variety of other uses including temperature-linked experimentation (41.7%), evaporating (37.0%), baking (16.5%) and sterilization (11.8%).
Freeze dryers find use in a variety of research and manufacturing environments and are commonly used for material storage, food and pharmaceutical processing, as well as for less common applications such as taxidermy and document recovery. With a wide variety of options available, there is much to consider when purchasing a new freeze dryer.
For the past 40 years scientists from all over the world have trusted Labconco Freeze Dry Systems to lyophilize and protect their assets. With sizes ranging from 1L to 18L and over 17 drying accessories available, FreeZone Freeze Dry Systems can be customized to lyophilize almost any type or size of sample. Don’t settle for just any lyophilizer, order a freeze dryer that you have selected specifically for your samples.
Problem: A variety of factors can result in obsolete laboratory equipment and R&D devices. Projectcompletion, equipment upgrade, lab closure, and downsizing all create surplus pharmaceutical assetsno longer required in the same capacity—or at all. Given budget restrictions and the importance placedon environmentally-sound business practices, organizations can’t afford to allow surplus assets to lieidle or dispose of them without thought to the process. Surplus requires an innovative and sustainableprocess that supports strategic business goals.
Problem: The human genome encodes thousands of secreted proteins, each of which is an actor inthe delicate biochemical balance of diagnostics. Even a slight change in any one of these proteins canmean the difference between sickness and health. Such a change also provides a critical window intothe body and helps to direct diagnosis and treatment, however, the vast majority of secreted proteinsare present in concentrations well below what conventional technologies can measure, and their role inhuman health is poorly understood.
Problem: Laboratories are faced with challenges when it comes to storing and tracking samples.