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Study: Exercise Increases Benefits of Breastmilk for Babies

Research builds upon previous finding in animals that maternal exercise improves offspring health

The Ohio State University Wexner Medical Center

A new study led by researchers at the Ohio State University Wexner Medical Center finds that even moderate exercise during pregnancy increases a compound in breastmilk that reduces a baby’s lifelong risks of serious health issues such as diabetes, obesity, and heart disease.

Findings from the study are published online June 29 in the journal Nature Metabolism.  

“We've done studies in the past that have shown that maternal exercise improves the health of offspring, but in this study, we wanted to begin to answer the question of why,” said lead author Kristin Stanford, associate professor of physiology and cell biology in Ohio State’s College of Medicine and a researcher in the Diabetes and Metabolism Research Center. “Because there is evidence that breastmilk plays a major role, we wanted to isolate the effects of breastmilk on offspring health.”

To do that, Stanford and her team studied mice born from sedentary mothers and fed them milk from mothers who were active throughout pregnancy. They found that the health benefits from fit moms transferred to the pups, showing that they were passed through breastmilk and not simply inherited genetic traits.


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A new study led by researchers at the Ohio State University Wexner Medical Center finds that even moderate exercise during pregnancy increases a compound in breastmilk that reduces a baby’s lifelong risks of serious health issues such as diabetes, obesity, and heart disease.
The Ohio State University Wexner Medical Center

Researchers also followed about 150 pregnant and postpartum women using activity trackers and found that those who had more steps per day had an increased amount of a compound known as 3SL in their breast milk, which they believe is responsible for these health benefits.

“The increases in 3SL were not necessarily related to exercise intensity, so even moderate exercise like a daily walk is enough to reap the benefits,” Stanford said. “Exercise is also great for your overall health during and after pregnancy, so anything you can do to get moving is going to benefit both you and your baby.”

Because many women are unable to breastfeed or experience complications that require bed rest, researchers are examining if they can isolate this beneficial compound found in the breastmilk of active moms and add it to infant formula.

“This human milk oligosaccharide had a significant impact on offspring health. Being able to add this into formula could provide benefits for babies when women aren't able to breastfeed,” Stanford said.

The team included researchers at the University of California, San Diego, the Arkansas Children’s Nutrition Center, and the Joslin Diabetes Center.