VIRUM, DENMARK — February 1, 2021 — Life Science Newswire — Immudex ApS has been collaborating with BD (Becton, Dickinson and Company) to create improved solutions for T-cell multi-omics research. The goal of this collaboration was to develop dCODE Dextramer® reagents compatible with the BD Rhapsody™ Single Cell Analysis system, a platform that analyzes the expression of hundreds of genes across tens of thousands of single cells in parallel.
Today, we are proud to announce the launch of dCODE Dextramer® (RiO) reagents. These DNA barcoded MHC Dextramer® reagents are designed to be compatible with the BD Rhapsody™ system to be used for multiplexing, allowing the identification of many different T-cell specificities in the same sample. Creating personalized dCODE Dextramer® libraries, is possible to profile T cells and get a new understanding of T-cell immunity.
"At Immudex, we are working with a clear goal in mind, helping researchers worldwide to get a better understanding of cellular immunity." Says Liselotte Brix, CSO at Immudex. "The immune system is complex, and there is still a lot to be discovered. dCODE Dextramer® (RiO) technology combined with the BD Rhapsody™ single-cell multi-omic analysis provides a deeper understanding of T cell immunology in a user-friendly workflow by combining information on TCR recognition with gene and surface marker expression at the single-cell level. Such information helps unlock new insights into the immune response, accelerating basic research, immunotherapeutic development, and improving patient outcomes."
The dCODE Dextramer® technology is an extremely sensitive method to directly detect disease-specific T cells based on TCR recognition and DNA barcode labels. Combining dCODE® technology with BD’s multi-omics solutions for immunology, researchers can obtain a full immunological profiling in one workflow and get the most of their experiments.
dCODE Dextramer® (RiO) reagents are for research use only, not for use in diagnostic or therapeutic procedures, and have been manufactured by Immudex ApS.