Overview: The Gibco LV-MAX Lentiviral Production System is the first optimized system that provides a scalable and high-yield lentiviral vector (LVV) production platform. It is based on a high-density suspension,culture of HEK 293-derived Viral Production Cells in chemically defined, serum-free and protein-free LV-MAX Production Medium. Optimal viral titer yield is mediated by our advanced lipid nanoparticle-based transfection reagent in combination with a novel lentiviral-specific enhancer and supplement. All components work synergistically to generate superior and functional lentiviral particles under serum-free conditions compared to conventional polyethylenimine (PEI), serum-based culture systems.
Key Applications: Cell and gene therapy research
- High titers—greater than 1 x 108 TU/mL (unconcentrated LVV-GFP)
- Scalable suspension system—lentiviral production from a 96 deep-well plate to a 2 L bioreactor
- Serum-free—eliminating animal-origin components and associated risks
- Cost-effective—over 50% cost reduction compared to PEI-based lentiviral production methods
Gibco LV-MAX Lentiviral Production System is for Research Use Only. Not for use in diagnostic procedures.
About Thermo Fisher Scientific
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