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Application Note

Automated Culture, Imaging, and Analysis of Angiogenesis

Automation of an organ-on-a-chip assay

3D cellular models are increasingly popular in many areas of research because they recapitulate the cellular 3D microenvironment better than cells grown in 2D monolayer. The current high failure rates of compounds in clinical studies could be due to the inadequacies of the 2D cell culture system. As such, there is a demand for more physiologically relevant models to enable better drug candidate selection in drug discovery.

In this app note, you’ll learn about:

  • Organoids and organ-on-a-chip (OoC) systems
  • Automation of cell seeding
  • Media exchange
  • Monitoring of quantification of 3D vasculature growth
  • Challenges associated with 3D cell culture

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