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Efficient Scale-up of Photoredox Coupling Reactions

Efficient Scale-up of Photoredox Coupling Reactions

Learn how photochemical flow reaction enabled chemists to scale a photoredox cross-coupling of boronic acids in 81% yield with gram per hour throughput

Uniqsis

The renowned Department of Chemistry at the University of Cambridge, UK has used a PhotoSyn flow photoreactor to efficiently scale-up a radical mediated boronic acid coupling under photoredox conditions utilising a novel organic acridium-based photocatalyst. The acridium-based organic photocatalyst, developed by the University of Cambridge, is demonstrated to be an efficient replacement for iridium-based photocatalysts used to oxidise boronic acid derivatives by a single electron radical coupling process.

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