White Papers and Application Notes

Preparation of Pharmaceutical Samples in Accordance with USP <232>/<233>

Preparation of Pharmaceutical Samples in Accordance with USP <232>/<233>

Utilizing single reaction chamber (SRC) sample prep technology for trace metals analysis of pharmaceutical samples

Milestone

With stricter industry regulations now in place, demand for trace metals analysis at lower detection levels has reached an all-time high. With ICP being rapidly replaced by ICP-MS, there is increased emphasis on sample preparation methodologies. While closed-vessel microwave digestion offers fast digestions, a clean environment, and effective recovery of volatile compounds, it has an inability to run digestion on several matrix types simultaneously.

This technical note demonstrates how single reaction chamber (SRC) microwave digestion can process large, dissimilar, and difficult samples without batching.