Top 5 Things You May Not Know About LC Systems

1. The Russian botanist Mikhail Tsvet is considered to have ‘invented’ the chromatographic technique in 1903 when he reported separations of different plant pigments into a series of colored bands on a packed column. He called this technique ‘chromatography.’

2. In the 1940s, Martin and Synge developed the theory of partition chromatography and used mathematics to describe the separation process resulting from the use of a liquid-coated solid phase and a moving liquid phase.

3. The technique of paper chromatography was developed by Consden, Gordon and Martin in 1944. This technique was originally used for the identification of amino acids.

4. J.C. Moore of the Dow Chemical Company was the first to investigate the technique of gel permeation chromatography, doing so in 1964.

5. The first commercial HPLC was manufactured by Waters Corporation in 1969, and was known as the ALC100 HPLC. The company also unveiled a new category of LC technology known as Ultra Performance LC (UPLC) in 2004.

Top 6 Questions You Should Ask When Buying an LC System

1. How flexible is the system? Ask about whether the system can be optimized to meet your laboratory requirements.

2. What tubes, vessels, vials can it accommodate? Can components (such as additional detectors, valves, etc.) be upgraded in the future?

3. Is the software easy to use and operate? Can a demo version be put in place to get a feel for how the software functions for your laboratory’s workflow?

4. How is the system (not just its components) qualified during installation as to meeting manufacturer performance expectations?

5. Who provides the support and service for the product? Is it the manufacturer or a third party service group? If it is a third party service group, are they factory-trained?

6. Finally, ask about cost of the purchase, installation charges, and warranty extension costs.

Recently Released LC Systems & Accessories

Nexera Method Scouting System

• Capable of automatically investigating up to 96 combinations of mobile phases, gradients and columns
• Improves HPLC method development productivity in both R&D and QA/QC environments
• Equipped with two pumps, each with a quaternary valve, which allows analysts to run binary gradients with 16 different solvent pairs
• Transfer program allows ultra-high-speed conditions to be transferred to conventional conditions

Shimadzu
www.ssi.shimadzu.com

New CDS Compatibility Dionex Instrument Integration (DII) Version 1.12

• Users of Thermo Scientific Dionex UltiMate 3000 series UHPLC and HPLC systems can now drive Thermo Scientific Dionex Corona Veo charged aerosol detectors and Thermo Scientific Dionex UltiMate 3000 ECD-3000RS electrochemical detectors with Waters Empower®
• DII enables control of these additional instruments on any LC system controlled by Empower for additional freedom in experimental design

Thermo Fisher Scientific
www.thermoscientific.com

1290 Infinity Multisampler UHPLC Autosampler

• Provides newly optimized, scalable throughput capacity that can process several thousand samples
• Fits within the standard Agilent LC-stack-footprint to minimize required lab space
• Offers a short injection cycle time, low carryover, and best-in-class cooling performance
• New software features improve workflow efficiency and enable easy data-entry of large sample sets

Agilent
www.agilent.com

HPLC Solvent Reservoir Kits

• Available in four sizes: 1000ml, 2L, 500 ml, and 5000 ml
• 1000 ml comes with a 1L solvent reservoir, cap and Teflon insert for 1/8” OD tubing, 1 meter 1/8” OD PTFE tubing and 10 μm 316 stainless steel frit
• 2L comes with 2L bottle, cap and Teflon insert for 1/8” OD tubing, 1 meter PTFE tubing and 10μm 316 stainless steel solvent frit—visit website for more info on other sizes

JM Science
www.jmscience.com

LC System Manufacturers