
6 Questions to Ask When Buying Chromatography Columns
- What are your analyte(s), matrix, separation goals, and instrumentation?
- What benefits does this column offer over your current column? Performance? Lifetime? Reproducibility?
- How should you clean/prepare your sample prior to injection on the column? 4 How do you look after the column? Conditioning, cleaning, storage, etc.
- What type of chromatographic media (fully porous, monolithic, core-shell) is going to provide the most benefit for your separation?
- Do you need a unique selectivity (HILIC, polar-end capped, etc.) to separate any very polar and/or non-polar components in your mixture?
- What column dimension is going to be most suitable for your loading requirement?
What's Your HPLC Column Usage?
| 0-1 per month | 50% |
| 2-5 per month | 30% |
| 6-10 per month | 5% |
| 10-50 per month | 9% |
| 50+ per month | 4% |
| Don't know | 2% |
Top 10 Features/Factors Respondents Look For When Purchasing HPLC Columns
| Technical Performance of HPLC Columns (e.g. Peak Shape) | 93% |
| Ruggedness/Durability of HPLC Columns | 90% |
| Lot-to-Lot Reproducibility of HPLC Columns | 83% |
| Initial Purchase Price of Column | 70% |
| Reputation of Column Manufacturer | 70% |
| Applications Support | 65% |
| Column Discount Program | 61% |
| Breadth of HPLC Column Offering (Selectivity) | 58% |
| Method Validation/Compliance Support | 57% |
| Specials and Promotions | 55% |










