Single-cell isolation is critical to numerous research areas, including rare-cell analysis, biologics discovery, and stem cell studies. Yet, the process of identifying and isolating productive single cells continues to be a hurdle, due in part to resource-intensive, low-success techniques like limiting dilution. These conventional methods can induce high levels of cell stress, compromising cell health, viability, and function, consequently impeding scientific progress.
Automated robotic instruments are revolutionizing scientific research and bringing more productivity and throughput to routine workflows, thus accelerating important discoveries. This eBook highlights how automated, image-based systems are simplifying progress in a variety of research applications.
Chapters highlight the workflow challenges of isolating circulating tumor cells (CTCs) following enrichment, isolating single clones for cell-line development, and gentle stem cell isolation. An expert interview further describes how automated single-cell detection and retrieval is shaping the future of biologics discovery.
In this eBook, you will discover:
- Methods for single-cell isolation of rare circulating tumor cells
- New automated approaches for single-cell isolation and cloning in cell-line development
- Advanced strategies for stem cell detection, isolation, and retrieval
- Applications of automated technology for single-cell retrieval