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Advion Launches Open Port Sampling Interface

Novel sample introduction enhances the analysis of proteins, peptides, and antibodies

by Advion
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ITHACA, NY / ACS, NEW ORLEANS, LA, March 20, 2018 /PRNewswire/ — Advion, Inc., a leading systems and consumables developer for the life sciences industry, announces the release of the Open Port Sampling Interface, or OPSI, designed for simple sampling of solids, liquids, and sample preparation tips and fibers. The novel ambient sampling technique was invented by Gary van Berkel and Vilmos Ketesz of Oak Ridge National Laboratory1. Paired with the electrospray ion source of the expression Compact Mass Spectrometer, the product incorporates an open port of continuous small-flowing volume of solvent directly into the mass spectrometer.  Any soluble sample touching the port is analyzed by the mass spectrometer in mere seconds. OPSI offers a fast assay benchtop solution for solid, liquids, and surfaces in a small-footprint, easy-to-use system. 

“OPSI extends our range of ambient ionization techniques to include anything soluble in normal mass spec solvents; non-volatile compounds such as biomolecules and polymers, sample preparation substrates on pipette tips, SPME techniques, and virtually any surface from which compounds can be harvested—and all with no sample preparation,” said David Patteson, Advion CEO. “This simple and robust sampling technique, combined with our compact mass spec, is ideal for many screening and compound identification applications, benefitting labs who require fast answers and a small footprint.”

Released at the 2018 ACS National Meeting and Expo in New Orleans, LA, the OPSI sample interface for the expression CMS is available for delivery now.

(1) An open port sampling interface for liquid introduction atmospheric pressure ionization mass spectrometry. Gary J. Van Berkel and Vilmos Kertesz, Rapid Commun. Mass Spectrom. 2015, 29, 1749–1756

About Advion, Inc.

Advion develops, manufactures, and globally supports mass spectrometers, novel sample introduction and assay solutions, chip-based ion sources, chromatography systems, microfluidic flow chemistry systems, and consumables for life science and related industries. We seek to enhance analysis performance and workflows. Using our deep scientific and engineering knowledge of mass spectrometry and microfludics, we leverage our passionate employees’ commitment to create quality, flexible, and fit-for-purpose solutions. More about Advion, Inc. can be found on our website,