Reduce carryover and ensure a high throughput LC/MS assay
Carryover is a phenomenon where you see a peak from the previous injection remaining in the current injection. When basic compounds are analyzed with a typical C18 column, their peak shape can become deformed (e.g., tailing) due to nonspecific interactions with residual silanols on the surface of the packing materials.
LC/MS/MS is one of the most powerful techniques for a quantitative assay due to its superior selectivity and sensitivity. Having a high-quality HPLC system to reduce carryover and ensure high throughput is essential for today’s laboratories.
This resource explores:
- How to optimize a front-end UHPLC system for higher throughput
- Critical features required for high-throughput LC/MS assays
Download the free infographic and white paper now to learn more about a future without carryover, courtesy of Shimadzu.
Carry the Day with No Carryover
Shimadzu LC designed to reduce carryover to your satisfaction
?Not a guarantee of absolute zero carryover
What is carryover?
Carryover is a phenomenon where you see a peak from the previous injection remaining in the current injection
Chromatogram
This is a visual representation of carryover. The blank injection that should have no peaks still detects chlorhexidine from the previous injection.
Look into the future without carryover
Present Batch
Future Batch
Time is saved and you will be able to
- Start the next batch earlier
- Run more samples
- Report results earlier