Reduce carryover and ensure a high throughput LC/MS assay
Carryover is a phenomenon where you see a peak from the previous injection remaining in the current injection. When basic compounds are analyzed with a typical C18 column, their peak shape can become deformed (e.g., tailing) due to nonspecific interactions with residual silanols on the surface of the packing materials.
LC/MS/MS is one of the most powerful techniques for a quantitative assay due to its superior selectivity and sensitivity. Having a high-quality HPLC system to reduce carryover and ensure high throughput is essential for today’s laboratories.
This resource explores:
- How to optimize a front-end UHPLC system for higher throughput
- Critical features required for high-throughput LC/MS assays
Download the free infographic and white paper now to learn more about a future without carryover, courtesy of Shimadzu.
