Laboratory centrifuge with swing-bucket rotor in motion processing multi-liter samples for bioprocess scale-up applications
Compendium

Eliminate Repeat Centrifuge Runs at Multi-Liter Scale

Compare rotor configurations and processing benchmarks across biomass harvesting, protein purification, viral vector production, and EV isolation

Written byEppendorf

Scaling centrifugation from flask culture to multi-liter bioreactor volumes creates a bottleneck of repetitive manual handling. Processing large batches across multiple runs increases time spent filling, balancing, loading, and decanting without improving yield or purity.

Centrifugation Strategies Compendium Thumbnail

This compendium organizes six white papers and application notes around consolidation strategies. It details how high-capacity rotor systems process six liters in one run, how zonal rotors cut AAV purification from 42 hours to eight hours, and how integrated workflows isolate extracellular vesicles in under four hours.

Download the compendium to:

  • See triangular bottle geometry effects on pellet recovery and supernatant decanting across bacteria and mammalian cell cultures
  • Review inline density gradient workflows that eliminate tube handling for viral vector and vaccine purification at 300+ mL volumes
  • Compare fixed-angle and swing-bucket performance data for protein yield, membrane integrity, and processing throughput

Sponsor

  • Eppendorf

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