Improve Your Solid Phase Extraction
Whitepaper

Improve Your Solid Phase Extraction

Top ten tips

Written byPorvair Sciences

Solid phase extraction (SPE) is a widely used technique designed for rapid, selective sample preparation and purification prior to chromatographic or LC/MS analysis. In SPE, one or more analytes from a liquid sample are isolated by extracting, partitioning, and/or adsorbing onto a solid stationary phase. Download this guide now to learn expert advice on how to improve your SPE results from just OK to great, every time.

This guide includes: 

Improve Your Solid Phase Extraction

  • Advice on selection of the best SPE sorbent to suit your analyte of interest  
  • How to optimise loading pH and the importance of refining wash and elution strength
  • Technical tips on how to set the best flow rate for a successful reverse phase SPE workflow
  • Explanation of the recovery and reproducibility benefits of composited SPE microplates and columns 
  • How to ensure an optimal dry down after solid phase extraction.

Top Image Credit:

CURRENT ISSUE - May/June 2025

The Benefits, Business Case, And Planning Strategies Behind Lab Digitalization

Joining Processes And Software For a Streamlined, Quality-First Laboratory

Lab Manager May/June 2025 Cover Image