Mass spectrometry (MS) is a highly versatile, core analytical technique that many fields rely on, ranging from chemistry to pharmaceuticals to materials science. Frequently combined with other analytical techniques, such as liquid chromatography, gas chromatography, nuclear magnetic resonance, and more to create powerful hybrid methods, the adaptability, sensitivity, and specificity of MS is critical for numerous applications. Whether applied to the identification and quantification of compounds, characterization of molecular structures, or other analyses, its high sensitivity and specificity demand meticulous sample preparation for successful outcomes. From benchtop instruments to automation solutions, there are many ways to optimize MS sample preparation to improve throughput, minimize costs, and achieve meaningful results.
Sample preparation requires several benchtop tools including pH meters, microwave digesters, and evaporators, among others. There are many factors to consider when selecting these instruments, especially what the analysis requires and what types of samples the lab will be working with now and in the future.
In addition to working with the right instruments, lab staff must possess the right knowledge and skills, and invest a significant amount of time and attention to ensure consistency. This manual approach to sample preparation can be costly, and is subject to human error. Automated solutions offer precision, consistency, and higher throughput, but require careful consideration—in the form of a feasibility study—to ensure a good return on investment.
Adopting green chemistry practices, like reducing or eliminating solvent use, can also reduce the costs associated with sample preparation. If a solvent-free method isn’t the right fit for your workflow, there are multiple tools available for solvent recycling.
Meaningful mass spectrometry results depend on meticulous sample preparation. The right tools and automation can enhance throughput, reduce costs, and ensure precision and consistency.
This resource guide includes detailed insights on instruments and techniques for mass spectrometry sample preparation. Learn what features to look for when selecting pH meters, microwave digesters, evaporators, and more for your sample preparation workflow. Not sure if automation is the right fit for your workflow? Learn how to conduct a feasibility study prior to implementing automation solutions. Also included is a comparison of solvent-free methods and solvent recovery/recycling options that can reduce the costs associated with mass spectrometry sample preparation.
Download the full resource guide to learn:
- Details insights on instruments and techniques for mass spectrometry sample preparation
- Features to look for when selecting pH meters, microwave digesters, evaporators, and more for your sample preparation workflow
- How to conduct a feasibility study prior to implementing automation solutions
- A comparison of solvent-free methods and solvent recovery/recycling options that can reduce the costs associated with mass spectrometry sample preparation
