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Nonacus Introduces ExomeCG Product to Simplify Molecular and Cytogenomics Data Generation and Interpretation

New capture kit product will enable whole exome sequencing and targeted copy number analysis in a single assay

by Nonacus
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BIRMINGHAM, UK — October 16,  2019 — Nonacus Ltd, a UK based precision medicine company and manufacturer of ultra-sensitive next-generation sequencing (NGS) products, has announced the launch of ExomeCG, a new product to simplify the generation and interpretation of molecular and cytogenomic data. 

The ExomeCG kit from NonacusThe ExomeCG kit from Nonacus.Credit: NonacusThe new product has been co-developed with digital health technology company, Congenica Ltd, which specializes in software solutions that enable accelerated interpretation of complex genomic data to improve disease diagnosis. 

ExomeCG is a clinically enhanced exome capture kit which, for the first time, will enable the genomics community to perform confident and robust whole exome sequencing and targeted copy number analysis in a single assay. The clinically validated test replaces the need for chromosomal microarray and multiplex ligation-dependent probe amplification (MLPA) front line tests, saving time and cost while achieving the highest diagnostic yield possible. 

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ExomeCG is designed to provide unparalleled coverage of clinical targets when used in combination with the Congenica® clinical decision support platform, which enables fast and accurate interpretation of NGS data for healthcare professionals to deliver world-class genomic medicine services and make important clinical decisions. Under the agreement Nonacus will supply the Congenica® software platform alongside the ExomeCG product and the wider Nonacus Cell3 Target™ product range, to provide an end-to-end solution for postnatal and prenatal analysis. 

Chris Sale, chief executive officer of Nonacus, said: “The launch of ExomeCG enables us to deliver a comprehensive clinical bioinformatics service to our customers and advance clinical cytogenomics by providing a robust, cost effective, and user-friendly laboratory and analysis workflow.The current cytogenomics paradigm typically requires a multi-test strategy whereby chromosomal microarrays are first run achieving a modest 15 percent diagnostic yield. Subsequently, exome sequencing is undertaken in order to raise the diagnostic yield to around 40 percent. ExomeCG now offers a validated single test solution, enabling customers to obtain the highest diagnostic yield while removing additional workflows and the associated time and costs.”