It’s official: Sample and standards preparation are significant bottlenecks in highthroughput laboratories, particularly those partly or fully automated. Improved instrument sensitivity—and the need for speed and accuracy—have made sample prep a top priority.
Yet discussing sample prep as a monolithic operation is impossible because prep steps, analyses, and matrices are highly variable among industries. Measuring protein levels in energy drinks is not the same as for granola; food safety analyzes for pesticide residues and microbial contamination; still other tests quantify trace nutrients. Matrix removal is a great idea, but even the “matrix” differs for all the tests mentioned.
Top 6 Questions You Should Ask When Buying HPLC Sample Prep Products (SPE)
![]() | ![]() | What is your sample matrix? |
![]() | What volume of sample do you need to extract? | |
![]() | What are your target analyte(s)? | |
![]() | What are your sample clean-up goals (high recovery vs. clean-up vs. speed)? | |
![]() | What sample preparation format is best for your work? | |
![]() | What is your mode of analysis (LC-UV, LC-MS-MS, GC-FID, GC-MS etc.)? |
Top 6 Questions You Should Ask When Buying a System for Chromatography Analysis Sample Prep
![]() | Can this system perform exhaustive extractions in about 10 minutes? |
![]() | Can this extraction system operate unattended overnight? |
![]() | Does the system change solvents and perform rinses automatically between samples? |
![]() | Does the extraction system comply with U.S. EPA methods? |
![]() | How does solvent consumption compare to other systems? |
![]() | Can the extraction system handle solid and semisolid and samples, or are multiple systems needed? |
Recently Released Chromatography Sample Prep Products
Metrohm Combustion Ion Chromatograp hy System
- Automates the determination of halogens and sulfur of various matrices across different industries
- Complies with environmental requirements, including DIN, EN, IEC, RoHS, WEEE and more
- Flame sensor technology measures the light intensity from the pyrolysis oven, controls the feed rate of the sample boat and prevents soot formation
- Combustion by one universal method
Metrohm
www.metrohmusa.com
Strata ® and Strata -X Tabless Tube Holder Accessories
- Hold SPE tubes in 96-well spacing to integrate with automated systems
- All Strata and Strata-X products are now available in the tabless 1 mL tube format, enabling the user to arrange multiple sorbents within the holders
- Allows users to remove and replace a single SPE tube should they make an error
Phenomenex
www.phenomenex.com
Microlute™ SPE Sample Preparation System
- Provides a faster, trouble-free alternative to cartridges for high throughput sample clean-up
- Handles samples as small as 150ul
- Includes filter plate, collection plate, waste tray and manifold
- Offers all the advantages of automated and high throughput SPE sample preparation in a convenient microplate format
- Capable of rapidly processing 96 samples in one go repeatedly and precisely
Porvair Sciences
www.porvair-sciences.com
EVOLUTE® EXPRESS 96-Well Plates
- Simplify polymer-based SPE by employing a streamlined 3-step protocol; Load-Wash-Elute
- Reduce processing and method development times without loss of analyte recovery or method robustness
- Design provides a uniform flow in the processing of aqueous samples and eliminates the need to re-run samples due to well-clogging
Biotage
www.biotage.com
Sample Prep for Chromatography Manufacturers
Agilent | www.agilent.com |
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BDH Chemicals | us.vwr.com |
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Biotage | www.biotage.com |
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Fluid Management Systems | www.fms-inc.com |
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Gilson | www.gilson.com |
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Horizon Technology | www.horizontech.com |
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Metrohm | www.metrohmusa.com |
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Perfinity Biosciences | www.perfinity.com |
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Phenomenex | www.phenomenex.com |
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Porvair Sciences | www.porvair-sciences.com |
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Shimadzu | www.shimadzu.com |
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Sigma-Aldrich | www.sigmaaldrich.com |
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Thermo Fisher Scientific | www.thermofisher.com |
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UCT | www.unitedchem.com |
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Waters | www.waters.com |