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Sphere Fluidics introduces Cyto-Cellect Human IgGK Detection Kit

Assay-ready reagent kit to reduce timelines and enhance efficiency in cell line development

by Sphere Fluidics
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Cambridge, UK, 9 September 2019 — Sphere Fluidics, a company commercializing single cell analysis systems underpinned by its patented picodroplet technology, today introduced the Cyto-Cellect™ Human IgGK Detection Kit, to be used in conjunction with the Cyto-Mine® Single Cell Analysis System for rapid and cost-effective measurement of antibody class and productivity in cell line development. 

Sphere Fluidics' Cyto-Cellect™ Human IgGK Detection KitSphere Fluidics' Cyto-Cellect™ Human IgGK Detection Kit.Credit: Sphere FluidicsThe Cyto-Cellect Human IgGK Detection Kit has been developed to provide Cyto-Mine users with an easy-to-use, standardized assay format for the detection of secreted human antibodies in picodroplets. The sensitive FRET-based assay rapidly detects the presence of human IgG with kappa light chain after secretion from encapsulated cells, to characterize and measure antibody production. Rapid detection of IgG enables high-throughput identification and selection of cells with the highest productivity for more efficient cell line development. 

With optimized ratios of Sphere Fluidics’ Human IgGK Detection probes, the Cyto-Cellect Human IgGK Detection Kit offers a sensitive and robust assay ideal for streamlining cell isolation and titer determination. The complete kit has been manufactured without the use of animal-derived materials, offering an animal-origin-free reagent kit that provides confidence in the reproducibility and consistency of the assay and conforms to regulatory requirements in cell line development. 

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“Our expert team has applied extensive knowledge of assay requirements to develop the Cyto-Cellect Human IgGK Detection Kit, offering users a sensitive, yet robust assay solution for the Cyto-Mine platform," said Dr. Zoe Nilsson, global product marketing manager, Sphere Fluidics. "The addition of this assay-ready kit to Sphere Fluidics’ product portfolio provides a rapid, yet cost-effective solution to further support and reduce cell line development timelines.” 

The Cyto-Mine platform will be on display in Boston, MA at BioProcess International from 9–12 September 2019 (Stand #1306). 

For more information about Sphere Fluidics’ Cyto-Cellect Human IgGK Detection Kit, please visit: