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Technology News - HPLC 2010

The latest equipment, instrument and system introductions to the laboratory market at HPLC 2010.

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HPLC 2010, the 35th International Symposium on High Performance Liquid Phase Separations and Related Techniques, runs from June 19 to June 24, 2010 at the Hynes Convention Center & Sheraton Boston Hotel in Boston, MA.

Here’s a sneak peek at some of the new products that will be showcased at HPLC 2010.

HPLC Columns
Booth 310

  • Available in 1.5, 3, 5 and 10 μm particle sizes in six different phase selectives spanning the full polarity spectrum
  • 12,000psi pressure rating is compatible with all ultra high-pressure LC systems
  • Offer increased polar interactions to make neutral, non-polar compounds elute faster and retain polar compounds longer
  • Instead of frits, thin screens retain media in the column, minimizing dead volume

Grace Davison Discovery Sciences

Product Spotlight Booth 509

Liquid Chromatography Columns
Glass-Lined or PEK-Lined for Optimal Peak Shapes

The ProteCol™ liquid chromatography columns from SGE Analytical incorporate high-quality stationary phases and inert materials throughout the flow path, offering such benefits as optimized analyte recovery, superior peak shape and reproducibility, and less artifacts due to reduced carryover. The ProteCol™-P features a PEEK™ lining and the ProteCol™-G features a glass lining to prevent contact with metal. PEEK or polymer frits are used.

“Certain compounds will react with metal,” said Rob Freeman, Business Manager – Chromatography at SGE Analytical. “By eliminating metal contact you get a better peak shape, which leads to increased sensitivity”

In addition to offering better peak shapes, ProteCol columns exhibit stability when exposed to pH 1.0 buffers and demonstrate consistent reproducibility of thousands of injections (subject to sample purity and mobile phase conditions).

ProteCol LC columns are available in a range of models for analyzing molecules with varying pore sizes. The HQ203 and HQ303 are packed with stationary phases of 200Å and 300Å, respectively, for analyzing peptides, while the HQ1003 uses a 1000Å pore size packing material, for separating larger proteins. The HPH125 model has a specially modified stationary phase, making it suitable for use outside commonly recommended pH ranges.

For more information, visit or visit SGE Analytical at HPLC 2010 in Boston, MA at booth 509. Rob Freeman, Business Manager – Chromatography, can be reached at 512-837-7190 ext. 104 or by e-mail at

Non-Porous ODS Column
Presto FF-C18
Booth 513

  • Compatible with polymers up to 30 MDa
  • Separates almost any polymer including bio-polymers and synthetic polymers
  • Achieves twice as many peaks as conventional ODS columns
  • Also able to separate and analyze polysaccharides

Imtakt USA

Evaporative Light Scattering Detectors
Booth 410

  • Suitable for a wide range of applications, including HPLC, LC/MS and SFC
  • Patented gas flow control system removes the mobile phase using a short evaporation tube
  • This gas flow technology reduces the evaporation time of the mobile phase at low temperatures by adding dry gas during evaporation, maintaining sharp peaks


UHPLC Columns
ACE® C-18-AR
Booth 411

  • Provide extra resolving power for a wide variety of sample mixtures
  • Exceptional bonded phase stability and ultra-low bleed characteristics make them suitable for LC/MS
  • Achieves baseline resolution of all compounds in a sample when other C18 columns fail
  • Bonded to the silica is a proprietary phase consisting of a C18 chain with integral phenyl functionality


High-purity Silica Phase for Preparative HPLC
Booth 710

  • Low bleed characteristics make it suitable for LC/MS
  • Features a long lifetime in acidic (pH 1) as well as basic (pH 10) mobile phases
  • Delivers exceptional transferability from analytical to preparative scale
  • Available in particle sizes 5 μm, 7 μm and 10 μm


Automated Powder Dosing
Quantos QB1
Booth 914

  • Designed for sample prep for analytical methods such as HPLC
  • Automates dosing of small quantities of free-flowing substances
  • Radio frequency identification (RFID) in the dosing head saves all information
  • Doses to 0.5 mg—with 0.005 mg readout accuracy

Mettler Toledo

Reversed-Phase Columns
Booth 111

  • Produced from macroporous PS-DVB beads with particle size 5 μm and 10 μm
  • Offer advantages such as lower back pressure and high permeability
  • Provide optimum pore volume and large pore size with high separating efficiency for large proteins, polypeptides, oligonucleotides and other macromolecules

BioChrom Labs

Micro-LC System
Booth 308

  • Designed to run 0.5 mm ID micro-columns at pressures up to 10,000 psi
  • Allows for the use of separation columns packed with
  • CCD-based detector offers higher UV sensitivity with full spectral capability
  • Features a binary gradient pump (flow rate range 1-50 μl/min) with solvent selection