Modern PLOT columns are engineered to provide stability and reproducibility:
Reproducibility
Using advances in technology PLOT column manufacturers are able to accurately control the process used to create the particles, enabling reproducible production of small particles with uniform diameter and pore size.
Stability
All of the particles are bonded to the tubing and/or to other particles, reducing particle generation. This reduces or eliminates detector spiking and changes in the flow characteristics through the column.
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