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2017 HPLC Survey Results

2017 HPLC Survey Results

Find out our readers’ most common HPLC applications and more from our latest survey results.

Erica Tennenhouse, PhD

Erica Tennenhouse, PhD, is the managing editor of Clinical Lab Manager.

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High-performance liquid chromatography (HPLC) is, for many scientists, an essential chromatographic technique. HPLC systems used for the separation, identification, purification, and quantification of various chemical and biochemical solutions are composed of a pump, a sample injector, a separation column, a detection unit, and a data-processor

Top 6 Questions You Should Ask When Buying an HPLC System

  1. How flexible is the system? Can the system be optimized to meet your laboratory requirements?
  2. What tubes, vessels, and vials can it accommodate? Can components (such as additional detectors, valves, etc.) be upgraded in the future?
  3. Is the software easy to use and operate? Can a demo version be put in place to get a feel for how the software functions for your laboratory’s workflow?
  4. How is the system (not just components) qualified during installation to meet manufacturer performance expectations?
  5. Who provides the support and service for the product? Is it the manufacturer or a third party service group? If it is a third party service group, are they factory-trained?
  6. Finally, ask about the total cost of the purchase—not just the price of the product being installed—but the total cost of ownership, which includes price, service expectations, warranty, etc.

Types of HPLC systems used by survey respondents:

Analytical HPLC93%
Ion Chromatograph25%
Preparative HPLC14%

HPLC separation modes utilized by survey respondents:

Reverse Phase76%
Normal Phase42%
Ion Exchange33%
Ion Chromatography25%
Ultra-High performance (UHPLC)25%
Size Exclusion (SEC)22%
Hydrophilic Interaction (HILIC)19%
Chiral 12%
Gel Permeation (GPC)10%
Ion Exclusion5%
Gel Filtration (GFC)4%

Nearly 49% of respondents are engaged in purchasing a new HPLC system. The reasons for these purchases are as follows:

Replacement of an aging system
Addition to existing systems, increase capacity
Setting up a new lab
First time purchase

Top 10 features/factors respondents look for when purchasing an HPLC system:

Quality of data87%
Precise and accurate flow rates69%
Availability of supplies and accessories62%
Service and support54%

For more information on HPLC systems, including useful articles and a list of manufacturers, visit

See the most recent survey results here