Inductively coupled plasma mass spectrometry (ICP-MS) is recognized as a key technique for the analysis of trace elements in a wide variety of sample types. However, using single quadrupole ICP-MS can result in unresolved spectral interferences and lead to biased or false positive results. This is especially true for monoisotopic or quasi-monoisotopic elements, such as arsenic, a key analyte in many regulated methods governing the safety of drinking water, foodstuffs or pharmaceutical products, for example.
Access the free toolkit to learn how interferences can affect the detection of most elements in the periodic table and how to overcome them.
