Nem Chau, Vietnemaese Fermented pork sausage sliced on a white tabletop with bowl of sauce

Nem Chua: The Natural Food Preservative Revolution

Vietnamese fermented pork, Nem Chua, could be the key to a safe, all-natural food preservative, helping reduce food waste and prevent foodborne illnesses.

Written byTrevor Henderson, PhD
Updated | 3 min read
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The Power of Nem Chua in Food Preservation

Nem Chua, a Vietnamese fermented pork delicacy, is typically consumed raw but remains safe to eat due to its unique fermentation process. The natural bacteria thriving within Nem Chua produce a special bacteria-killing compound, preventing harmful pathogens from contaminating the meat.

Researchers at RMIT University in Melbourne, Australia, have recently discovered how this naturally occurring compound could revolutionize food preservation, providing a safer and more sustainable alternative to artificial preservatives.

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Addressing Global Food Challenges

Food waste and foodborne illnesses are two significant global issues:

  • Food waste costs $680 billion annually in industrialized nations, consuming nearly 25% of agricultural water and contributing 8% of global greenhouse emissions (FAO, 2013).
  • Foodborne diseases like Listeria and Salmonella impact millions each year, posing severe risks for pregnant women, elderly individuals, and those with weakened immune systems.

With an increasing consumer preference for natural preservatives, scientists are investigating how Nem Chua’s antibacterial properties can be leveraged to enhance food safety and extend shelf life.

How Nem Chua Protects Against Harmful Bacteria

Nem Chua's effectiveness in eliminating pathogenic bacteria is attributed to a newly identified bacteriocinPlantacyclin B21AG. This compound is part of a broader class of antimicrobial agents that naturally occur in bacteria, enabling them to eliminate rival bacterial strains.

The Science Behind Bacteriocins

Bacteriocins work by forming holes in the membranes of harmful bacteria, causing cell contents to leak out and effectively destroying the microorganism. However, most bacteriocins are highly specific, affecting only a limited range of bacterial strains and lacking stability in various food environments.

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A Breakthrough in Natural Food Preservatives

The only bacteriocin currently approved for food preservation is Nisin, introduced in the 1960s. While widely used, Nisin has limitations, as it is sensitive to temperature and pH fluctuations, restricting its application across diverse food products.

In contrast, Plantacyclin B21AG from Nem Chua has proven to be:

  • More stable than Nisin, retaining potency in extreme conditions.
  • Effective against a wide range of bacteria, including foodborne pathogens such as Listeria.
  • Resistant to heat, surviving temperatures up to 90°C for 20 minutes.
  • Stable across various pH levels, ensuring efficacy in diverse food environments.

Potential Applications of Nem Chua’s Antibacterial Compound

The newfound stability and effectiveness of Plantacyclin B21AG suggest promising applications in both food and medical industries:

ApplicationPotential Benefits
Food PreservationExtends shelf life naturally, reduces artificial additives
Dairy ProductsPrevents spoilage in cheeses, yogurts, and other fermented foods
Meat and SeafoodEnhances food safety by preventing bacterial contamination
PharmaceuticalsMay serve as an antibiotic alternative, combating drug-resistant bacteria

Scaling Up Production for Industrial Use

A major challenge in using bacteriocins like Plantacyclin B21AG as food preservatives has been producing them at commercially viable levels. However, RMIT researchers have developed a system for scaling production:

  1. Optimizing growth conditions to increase the yield of the bacteriocin.

  2. Enhancing purification methods for potential industrial application.

  3. Testing incorporation into food products to validate effectiveness and safety.

"Scientists have known about these bacteria-killing compounds for many years, but the challenge is to produce them in large enough quantities for the food industry," said Professor Oliver Jones, Associate Dean of Biosciences and Food Technology at RMIT University.

Future of Natural Food Preservatives

As research continues, Plantacyclin B21AG could become a natural, safe, and effective food preservative with global applications. Beyond food, it may also serve as a foundation for new antibiotic alternatives, addressing concerns over antimicrobial resistance.

"Using bacteriocins as food preservatives effectively means we are turning bacteria's own toxic weapons against them—harnessing nature's smart solutions to tackle our big challenges," said Dr. Elvina Parlindungan, lead researcher at APC Microbiome.

Conclusion: Nem Chua’s Role in the Future of Food Safety

The potential of Nem Chua to combat food waste and foodborne illnesses highlights its importance in the future of food safety and preservation. By harnessing the natural antibacterial properties of Plantacyclin B21AG, researchers are paving the way for healthier, more sustainable food preservation techniques.

Key Takeaways

  • Nem Chua contains Plantacyclin B21AG, a bacteriocin that destroys harmful bacteria.
  • Unlike Nisin, this compound is highly stable, working across extreme temperatures and pH levels.
  • Potential applications include food safety, dairy preservation, and medical use as an antibiotic alternative.
  • Scaling up production is a key research focus to enable mass adoption in the food industry.

With continued research, Vietnamese fermented pork could revolutionize how we preserve food naturally, reducing dependence on chemical additives while improving food safety worldwide.


This content includes text that has been generated with the assistance of AI. For more information, view Lab Manager’s AI use policy


About the Author

  • Trevor Henderson headshot

    Trevor Henderson BSc (HK), MSc, PhD (c), has more than two decades of experience in the fields of scientific and technical writing, editing, and creative content creation. With academic training in the areas of human biology, physical anthropology, and community health, he has a broad skill set of both laboratory and analytical skills. Since 2013, he has been working with LabX Media Group developing content solutions that engage and inform scientists and laboratorians. He can be reached at thenderson@labmanager.com.

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