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HPLC Detectors

An appropriate HPLC detector has the ability to sense the presence of a compound and send its corresponding electrical signal to a computer data station.

by Lab Manager
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 An appropriate HPLC detector has the ability to sense the presence of a compound and send its corresponding electrical signal to a computer data station. The choice of a detector depends upon the characteristics and concentrations of the compounds that need to be separated and analyzed.


“Diode array detectors on the market today vary considerably in performance specifications and pricing. Researchers need to consider what they truly need - as it can dramatically impact the price they will pay,” says Moroni Mills, Senior Marketing Specialist, Gilson, Inc.





The 1200 Series diode array detector SL delivers multiple wavelength and full spectral detection at sampling rates up to 80 Hz, accommodating even ultrafast liquid chromatography. At high data rates, the 1200 Series DAD SL still provides precise identification, quantification, and peak purity analysis at trace levels. This exceptional performance is particularly useful when ultrafast LC methods must comply with strict regulatory requirements. The unit provides an expanded detection range, 190 nm to 950 nm, with the lowest detection limit. Low-noise front-end electronics and a new patented flow cell design deliver lowest detection limits as a result of minimized short-term noise (typical < 6 μAU ASTM).


Agilent 1200 Series


Gilson, Inc.

The recently released Gilson 171 and 172 diode array detectors deliver rugged and accurate detection for both preparative and analytical HPLC. Both detectors utilize fiber-optic technology that allows for a fixed or remote flow cell. The remote flow cell can be positioned up to 1 meter outside the detector housing, allowing the cell to be connected almost directly to the HPLC column output. This provides ultrafast detector response and minimal band broadening. The detectors are fully supported in Gilson's TRILUTION® LC software with spectral library creation, 3D, and iso-electric plots, as well as spectrum and visual peak purity display.


Gilson 171 and 172




All of JASCO LC-2000 plus series HPLC detectors use state-of-the-art digital signal processing to further improve signal-to-noise performance. The MD-2010/2015 diode array detector is no exception, with a range from 195 to 650 nm (MD-2010) or from 200 to 900 nm (MD-2015) and a wide variety of cell options. This detector offers six- Wavelength chromatograms, ratio chromatograms for peak purity, 3-D chromatograms, contour plots, and UV-Vis spectra, as well as a full-spectral library and easy-to-use search feature.


 JASCO HPLC Detector



The ACQUITY UPLC® photodiode array (PDA) detector allows laboratories to detect and quantify lower concentrations of sample analytes and compare spectra across wavelengths and broad concentration ranges. It has data rates of up to 80 Hz, noise specifications of 10 μAU, and an extended linear range. With the PDA detector, users can fulfill multiple UltraPerformance LC®/MS detection strategy requirements for the identification of components that are difficult to resolve by conventional HPLC-based methods. Trace impurities at levels to 0.004% with low signal-to-noise ratios, high optical and digital resolution, and library matching can be quantified.


 PF Waters



If you are in the market for new HPLC Diode Array Detectors, Lab Manager and LabX can have qualified companies contact you directly. 
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