Ovarian cancer is the most lethal gynecological malignancy and therapeutic options remain limited

“We are just starting to appreciate that the way our genome is spatially organized in our cells has a profound impact on its function,” says lead author

Most vaccines targeting tumor-associated antigens have had limited success so far in producing therapeutic effects against most cancers due to poor immunogenicity

The current Zika virus outbreak, which began in 2015 and is spread through mosquito bites and sexual intercourse, has been confirmed in 47 countries and has affected 1.3 billion people around the world

In this preclinical study, 100 percent of the animal models were protected from Zika after vaccination followed by a challenge with the Zika virus