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Preserving Sample Integrity in Cold Storage
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Preserving Sample Integrity in Cold Storage

Effective storage and preservation of biological samples with high integrity is essential to research, the development of life-saving therapeutics, and personalized medicine

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Biobanking and cold storage play a pivotal role in ensuring that specimens are kept in optimal conditions for long-term study and use. 

However, there are significant challenges when it comes to consistency around the quality and integrity of samples in cold storage. Issues such as temperature fluctuations, transient warming events, and molecular-level interactions can all contribute to the degradation of sample integrity in sensitive biological materials. Understanding the science behind these risks can help researchers mitigate risks like ice recrystallization, enzymatic activity, and find success in maintaining the viability of stored samples 

This webinar session with Azenta Life Sciences features three expert speakers—Dr. Alison Hubble, Dr. Jason Acker, and Kathi Shea—providing their takes on the scientific, technological, and operational aspects of biobanking, and the proper management of these systems in research labs, clinical facilities, and wherever biospecimen storage is critical to success. 

By watching this webinar, you will learn more about: 

  • Practical strategies for maintaining sample integrity in cold storage over long periods
  • How molecular-level interactions play a crucial role in sample preservation and how to identify early markers for sample damage 
  • The risks associated with transient warming events and the impact of ice recrystallization on sample quality
  • How cryoprotectants can play a key role in sample stabilization during cold storage, minimize damage, and extend sample viability 
  • The “four T’s” of cold chain management focusing on time, temperature, tools, and techniques, to develop best practices in cold storage 
  • Critical factors like freezer type, transient warming mitigation, and proper equipment validation to improve sample preservation and avoid costly errors

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