Laser diffraction is a widely recognized technique for particle characterization offering precise measurements of particle size distributions in various materials. The technique’s versatility, speed, and non-destructive nature have made it a crucial tool in research and industrial quality control, but it is also accompanied with its fair share of challenges.

Developing methods for laser diffraction can be challenging especially with new sample types. Researchers often face uncertainty in procedure steps, and without immediate access to expert advice, they might resort to "best guesses" that could lead to errors. In practice, samples for laser diffraction analysis often contain contaminants such as bubbles, aggregates, or particles that adhere to surfaces. These transients can skew the particle size distributions (PSDs), leading to misleading results and reduced reproducibility. This issue is especially problematic during routine measurements and method development, where it can derail the optimization process and waste valuable time. Lastly, achieving high data quality in laser diffraction can be difficult due to issues like poor reproducibility, unstable backgrounds, or unexpected sample agglomeration. Identifying the root cause of these problems can be time-consuming, particularly for those less familiar with the technique.
Malvern Panalytical’s Mastersizer 3000+ is equipped with advanced features including Data Quality Guidance, Size Sure, and SOP Architect that address these challenges helping enhance the reliability of particle analyses and streamline method development. By assisting with method development and ensuring data quality, the Mastersizer 3000+ empowers researchers to achieve reliable results with greater efficiency and confidence, ultimately advancing their work in a range of applications from pharmaceuticals to materials science.
Read this resource to learn more about:
- Optimizing your particle analysis workflow with laser diffraction using Mastersizer 3000+’s advanced features.
- Troubleshooting poor quality data using real-time feedback and recommendations, reducing the need for external assistance and preventing workflow delays.
- Exploring Masterizer 3000+’s suite of advanced features such as Data Quality Guidance, Size Sure, and SOP Architect to enhance and embed best practices into your particle analysis workflows.
- Resolve challenges surrounding contamination, accuracy, data quality, sample preparation and method repeatability for laser diffraction assisted particle analysis.
Download this resource bundle to incorporate a consistent, robust, and error-free particle analysis in your laboratory workflow.