At or below the -130°C glass transition temperature of water, metabolic activity in the cell is suspended indefinitely and viability of properly prepared cell cultures is protected. Previously, liquid nitrogen offered the only method of cryogenic storage either in liquid (liquid phase) or liquid nitrogen vapor (vapor phase). With mechanical refrigeration, a more efficient storage medium known as “air phase” offers a more economical alternative to liquid nitrogen-based systems, with built-in redundancy safeguards for the ultimate in safe cryogenic preservation.

Download this application note to learn more about the benefits of mechanical refrigeration, courtesy of PHCbi.