Image of laboratory chemicals on a shelf displaying proper chemical labeling

The Dos and Don'ts of Chemical Labeling in the Laboratory

At a recent chemistry meeting, a question came up concerning the proper method of labeling a chemical container. Of the 24 chemistry teachers in attendance, not one of them was sure what kind of information was required on a chemical label.

Written byTrevor Henderson, PhD
Updated | 4 min read
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Chemical labeling is a fundamental aspect of laboratory operations, ensuring safety, regulatory compliance, and efficient workflows. Proper labeling helps prevent chemical misuse, reduces the risk of accidents, and facilitates safe handling and storage. Whether it involves identifying hazardous substances or ensuring compatibility with OSHA and GHS standards, accurate labeling is essential for a well-functioning lab. This guide outlines the critical dos and don’ts of chemical labeling to promote best practices and enhance safety within laboratory environments.


Why Is Proper Chemical Labeling Important?

Proper chemical labeling protects laboratory personnel, ensures compliance with regulations such as OSHA’s Hazard Communication Standard, and prevents costly mistakes. Mislabeling or failing to label chemicals can lead to:

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  • Accidental chemical misuse
  • Dangerous reactions or spills
  • Non-compliance penalties
  • Inefficient lab operations

By adhering to clear labeling protocols, laboratories can maintain a safe, organized, and compliant work environment.


The Dos of Chemical Labeling

Follow these best practices to ensure effective chemical labeling in your laboratory:

  1. Label All Containers:

    1. Ensure every chemical container, including secondary containers, has a label. No container should be left unidentified. Clearly identify temporary containers used during experiments to avoid confusion and maintain safety.

  2. Include Key Information:

    1. Clearly display the chemical name, concentration, and any hazards. Use full names rather than abbreviations to avoid confusion. Add expiration dates or storage conditions when applicable to ensure safe handling.

  3. Use Durable Labels:

    1. Select labels that are waterproof, chemical-resistant, and adhesive enough to withstand laboratory conditions. For environments with extreme temperatures or exposure to solvents, ensure the material used for labeling can withstand these factors.

  4. Follow Regulatory Standards:

    1. Ensure labels comply with OSHA’s Hazard Communication Standard and, where applicable, GHS (Globally Harmonized System of Classification and Labeling of Chemicals) requirements. Regularly review updates to these standards to stay compliant.

  5. Incorporate Hazard Symbols:

    1. Include hazard symbols such as flammable, corrosive, or toxic to provide a quick visual warning. These symbols should match international standards to ensure universal understanding.

  6. Maintain Legibility:

    1. Use clear, legible fonts and ensure the label is not obstructed by tape or other materials. Avoid handwritten labels unless they are neat and concise.

  7. Update Labels When Necessary:

    1. Revise labels promptly if the chemical is transferred, diluted, or has been stored for an extended period. Outdated labels can lead to improper usage and safety hazards.

  8. Train Personnel:

    1. Educate all lab members on the importance of proper labeling and how to identify and handle labeled chemicals. Provide training on interpreting hazard symbols and understanding GHS requirements.


The Don’ts of Chemical Labeling

Avoid these common pitfalls to maintain safety and compliance:

  1. Don’t Use Generic Labels:

    1. Labels such as “Acid” or “Solvent” are too vague. Always provide specific chemical names and details to ensure proper identification and handling. Generic labels can lead to serious safety issues, particularly in cases where similar compounds have vastly different properties.

  2. Don’t Skip Labeling Temporary Containers:

    1. Even if a container is used briefly, it must be labeled to prevent confusion or accidents. Unlabeled temporary containers increase the risk of misidentification and can result in improper disposal or dangerous chemical reactions.

  3. Don’t Cover Existing Labels:

    1. Avoid placing new labels over existing ones, as this can obscure important information. Instead, remove old labels entirely before applying new ones to maintain clarity and prevent miscommunication about the container's contents.

  4. Don’t Rely on Memory:

    1. Never assume you will remember the contents of an unlabeled container. Over time, memory fades, and what seems obvious now may not be apparent later, increasing the likelihood of misuse or disposal errors

  5. Don’t Use Abbreviations:

    1. Avoid non-standard abbreviations that may not be understood by others. If abbreviations are used, ensure they are universally accepted or clearly defined within the laboratory’s documentation to prevent confusion.

  6. Don’t Ignore Fading Labels:

    1. Replace any labels that have become faded, torn, or illegible. Over time, exposure to chemicals or light can degrade labels, making them difficult to read and increasing the risk of accidents.

  7. Don’t Mix Old and New Labels:

    1. Ensure all labels follow a consistent format to avoid confusion. Mixed labeling systems can create discrepancies, particularly during audits or emergencies, and make it harder for personnel to quickly identify chemicals.


Laboratory Labeling Requirements

To maintain compliance, laboratories must adhere to the following requirements:

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  1. OSHA Hazard Communication Standard:

    1. Labels must include the chemical name, signal words (e.g., “Danger” or “Warning”), hazard statements, precautionary statements, and pictograms. These elements communicate essential safety information, ensuring that all personnel understand the potential risks and required precautions for handling each substance. Compliance with this standard not only protects employees but also reduces liability for the organization.

  2. Globally Harmonized System (GHS):

    1. GHS requires a consistent labeling format with standardized symbols and classifications to enhance global safety. By using universally recognized pictograms and hazard classifications, GHS improves cross-border chemical safety, ensuring that personnel worldwide can easily understand and handle labeled chemicals.

  3. Secondary Container Labeling:

    1. Secondary containers, such as spray bottles or flasks, must have labels that match the original container’s information. This ensures continuity of information, reducing the risk of accidental misuse or mishandling when chemicals are transferred between containers.

  4. Periodic Inspections:

    1. Conduct regular audits to ensure all containers are properly labeled and that labels are intact and legible. Inspections help identify and rectify issues such as fading labels, missing hazard information, or improper labeling practices before they lead to safety incidents.

  5. Emergency Information:

    1. Include emergency contact information or reference materials, such as SDS (Safety Data Sheets), near labeled chemicals. Having this information readily available ensures that laboratory personnel can respond quickly and appropriately in the event of an emergency, minimizing potential harm.


Frequently Asked Questions

1. What should I do if a chemical label becomes illegible?

Replace the label immediately. Ensure the new label contains all required information, such as the chemical name, hazards, and precautionary measures.

2. Are secondary containers required to be labeled?

Yes, all containers, including temporary and secondary ones, must be labeled to avoid confusion and maintain compliance with OSHA and GHS standards.

3. Can I use abbreviations or chemical formulas on labels?

While chemical formulas may be used in addition to full names, avoid using abbreviations unless they are standardized and universally understood by your team.


Final Thoughts

Chemical labeling is a fundamental aspect of laboratory safety and efficiency. By following these dos and don’ts, adhering to regulatory standards, and training personnel, laboratories can ensure accurate identification and safe handling of all chemicals. Proper labeling not only minimizes risks but also fosters a culture of responsibility and compliance within the lab environment.


This content includes text that has been generated with the assistance of AI. Lab Manager’s AI policy can be found here.

About the Author

  • Trevor Henderson headshot

    Trevor Henderson BSc (HK), MSc, PhD (c), has more than two decades of experience in the fields of scientific and technical writing, editing, and creative content creation. With academic training in the areas of human biology, physical anthropology, and community health, he has a broad skill set of both laboratory and analytical skills. Since 2013, he has been working with LabX Media Group developing content solutions that engage and inform scientists and laboratorians. He can be reached at thenderson@labmanager.com.

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