Waters Corporation has announced availability of a new application note detailing rapid analysis of 402 pesticides in a single 10-minute run using Waters ACQUITY^® TQD, liquid chromatography combined with tandem quadrupole mass spectrometry (UPLC/MS/MS) operated in Multiple Reaction Monitoring (MRM) mode, and Waters MassLynx™ Software with IntelliStart™ technology for data acquisition and MS parameters optimization.

"Publishing this application note provides food safety laboratories faced with challenging multi-residue pesticide analysis with a proven analytical method, not just merely a software capability claim," said James Willis, Managing Director, Chemical Analysis, for Waters Division

On July 24, the U.S. Environmental Protection Agency banned the use of carbofurans. The agency wrote, "Due to considerable risks associated with the pesticide carbofuran in food and drinking water, EPA is revoking the regulations that allow carbofuran residues in food. Even though carbofuran is used on a small percentage of the U.S. food supply and therefore the likelihood of exposure through food is low, EPA has identified risks that that do not meet our rigorous food safety standards."

Advances in chromatographic separation and detection technologies have enabled analysts to increase the number of analytes determined in a single run. Tandem quadrupole mass spectrometry offers a highly specific and selective detection technique that has become the technique of choice within the laboratory. Many countries have strict regulations governing pesticides covering import, export and domestic produce. Legislation-imposed Maximum Residue Limits (MRLs) for pesticide residues in food products require analytical techniques that are sensitive, selective, and robust.  The need to meet mandated detection limits, develop generic sample preparation techniques for complex matrices, the need for accuracy, and the desire to increase sample throughput are the main challenges facing food safety testing laboratories today. The use of a reproducible single multi-residue analytical method can dramatically improve return on investment by removing the guesswork out of pesticide analyses.

The Rapid Method for the Screening and confirmation of Over 400 Pesticide Residues in Food application note, including a complete list of pesticides, can be found on Waters' Web site at: http://www.waters.com/waters/library.htm?cid=511436&lid=10069469.

Source: Waters Corporation