Chemical storage safety is critical in laboratories, research facilities, and industrial settings. A failure to properly store hazardous chemicals can lead to spills, toxic exposures, fires, explosions, and severe health risks.

A real-life example from 2005 illustrates this danger: A university student was unloading hexane into a solvent storage cabinet when the shelf collapsed. This led to chemical exposure, evacuation, and ultimately a lab explosion that damaged adjacent facilities. The cause? A simple oversight in chemical storage safety.

To prevent such incidents, laboratories must adhere to strict chemical storage protocols. The Environmental Safety Division of the University of Georgia has identified 8 fundamental elements every chemical storage plan should include.

8 Fundamentals of Chemical Storage Safety

1. Store Chemicals by Hazard Class

Different chemicals pose unique hazards and should be stored separately based on their hazard classification. Common hazard classes include:
✔ Flammables (e.g., ethanol, acetone)
✔ Oxidizers (e.g., hydrogen peroxide, nitric acid)
✔ Health hazards/toxins (e.g., cyanides, heavy metals)
✔ Corrosives (e.g., hydrochloric acid, sodium hydroxide)

🔹 Example: Never store oxidizers near flammable materials, as this can increase fire risks.

2. Keep Chemicals Away from Heat and Sunlight

Exposure to direct sunlight, localized heat sources, and hot surfaces can cause:
✔ Degradation of sensitive compounds
✔ Pressure buildup in sealed containers
✔ Increased volatility, raising fire and explosion risks

🔹 Example: Peroxide-forming chemicals like diethyl ether should be kept in cool, dark storage areas to prevent dangerous reactions.

3. Label and Date All Chemical Containers

✔ Every chemical should be clearly labeled with:

• Name
• Concentration
• Hazard classification
  ✔ Date of receipt and date of opening must be noted.
  ✔ Expiration dates should be closely monitored, particularly for unstable substances.

🔹 Example: Peroxide-forming chemicals (e.g., tetrahydrofuran) should have a clearly marked expiration date to prevent dangerous peroxide buildup.

4. Store Hazardous Chemicals Below Shoulder Height

✔ Chemicals should be stored below the shortest lab worker’s shoulder height to reduce:

• The risk of accidental spills when retrieving items
• Direct exposure in case of breakage

🔹 Example: Strong acids like sulfuric acid and concentrated hydroxide solutions should be stored on low, sturdy shelves or in corrosive cabinets.

5. Use Chemical-Resistant Shelving

✔ Shelves should be made of chemically resistant materials to prevent corrosion and degradation.
✔ Metal shelves should have a protective coating, while wood shelves should be chemically treated.

🔹 Example: A spill of nitric acid on untreated metal shelving can corrode the structure, leading to dangerous chemical leaks.

6. Ensure Shelves Are Secure and Not Overloaded

✔ Shelving must be strong enough to support all stored chemicals.
✔ Avoid overloading shelves, which can cause collapses or spills.
✔ Ensure shelves have spill containment trays when handling liquids.

🔹 Example: A weak shelf in a flammable cabinet could collapse, mixing oxidizers and fuels, leading to a fire hazard.

7. Train Lab Personnel on Chemical Hazards

✔ All personnel should be trained on proper handling and storage of chemicals.
✔ Regular safety drills should be conducted to prepare for spills, fires, or exposures.
✔ Labs should have clear, visible safety labels and signage.

🔹 Example: In case of a cyanide spill, workers must know proper emergency protocols to avoid toxic exposure.

8. Separate Solid and Liquid Chemicals

✔ Storing solids and liquids separately reduces cross-contamination risks.
✔ Solids should be kept in sealed containers away from moisture-sensitive areas.

🔹 Example: Sodium metal (solid) reacts violently with water, so storing it near liquid chemicals increases the risk of a dangerous reaction.

Chemical Storage Guidelines for Specific Hazard Classes

Acids

Acids are commonly used in titrations, chemical synthesis, and pH control. Strong acids like hydrochloric acid (HCl) and sulfuric acid (H₂SO₄) are highly corrosive and can cause severe burns or toxic gas formation when mixed with incompatible substances.

✔ Store organic and inorganic acids separately to prevent dangerous reactions.
✔ Keep concentrated acids on low shelves or in corrosive-resistant cabinets.
✔ Isolate acids from bases, active metals, and chemicals like sodium cyanide to avoid hazardous gas formation.

Bases

Bases, such as sodium hydroxide (NaOH) and potassium hydroxide (KOH), are widely used in neutralization reactions and chemical synthesis. They are highly caustic and can cause chemical burns.

✔ Store bases separately from acids to prevent neutralization reactions.
✔ Use secondary containment trays in case of leaks.

Flammable Liquids

Flammable chemicals, including ethanol, acetone, and toluene, are used as solvents, cleaning agents, and reaction mediums. These materials ignite easily, making safe storage critical.

✔ Store flammables in approved flammable cabinets.
✔ Limit flammable storage to 20 gallons per 100 sq. ft.
✔ Use explosion-proof refrigerators for flammable chemicals.

Peroxide-Forming Chemicals

Peroxide-formers, such as diethyl ether and tetrahydrofuran (THF), are used as solvents in extractions and reactions. Over time, they can form shock-sensitive peroxides, which may detonate unexpectedly.

✔ Store in airtight, opaque containers in cool, dark locations.
✔ Label expiration dates and dispose of them before peroxides accumulate.

Water-Reactive Chemicals

Water-reactive chemicals, such as sodium metal and lithium aluminum hydride (LAH), react violently with water, often producing flammable hydrogen gas or explosive reactions.

✔ Store in cool, dry locations away from moisture.
✔ Do not store under sinks or near humid environments.
✔ Keep Class D fire extinguishers nearby.

Oxidizers

Oxidizers, like hydrogen peroxide and potassium permanganate, enhance combustion and can cause materials to ignite spontaneously.

✔ Store away from flammables, combustibles, and reducing agents.

Toxins

Toxic compounds, such as mercury compounds and cyanides, are highly hazardous and require strict safety measures.

✔ Store in secure areas with restricted access.
✔ Post Poison Control Network contact information for emergencies.

Conclusion: Prioritizing Chemical Storage Safety in the Laboratory

Implementing a comprehensive chemical storage plan minimizes risks, prevents accidents, and ensures compliance with safety regulations.

Would your lab benefit from a safety review of chemical storage procedures? Implement these strategies today for a safer and more efficient work environment.