The role of TIMS-MS in ensuring high purity in biopharmaceuticals

july21-BigPic-Pharma-Bruker-Header-1900x785

Theoretical vs measured abundance (mean average) of simulated HCPs in % of 4 ng UPS2 in 200 ng NISTmAb

Number of unique peptides identified for HCPs using (A) native digest and UPLC-MS/MS (yellow) and TIMS QTOF-MS/MS (blue); and (B) HILIC fractionation and UPLC-MS/MS (orange) and TIMS QTOF-MS/MS (blue).

Number of unique peptides identified for HCPs using (A) native digest and UPLC-MS/MS (yellow) and TIMS QTOF-MS/MS (blue); and (B) HILIC fractionation and UPLC-MS/MS (orange) and TIMS QTOF-MS/MS (blue)

Removing host cell proteins from biologic products is vital to protect drug efficacy, stability, and safety

The Role of TIMS-MS in Ensuring High Purity in Biopharmaceuticals

Insights

Lab Manager January/February 2026 Cover Image

january-february-2026-how-to-build-trust-into-every-lab-result

Applying the Six Cs Helps Labs Deliver Results Stakeholders Can Rely On

How to Build Trust Into Every Lab Result

Stuart Pengelley

transferpette-product-image

Scientist using an ergonomic and precise pipette

transferpette-pro-image-900x600

tfp-pro-top-finger-rest-rotation-high-res-300dpi

transferpette-pro-user-adjustment-300dpi

tfp-pro-sc-10-l-300dpi

tfp-pro-series-high-res-300dpi

logo-brandtech

BRANDTECH Scientific

A New Twist on Comfort and Control with the BRAND&reg; Transferpette&reg; pro Pipette

sapio-lims-thumb

ELN and AI integration visualization showing the technological shift in modern pharma lab notebooks

adobestock-844440649-sapio-ppl

sapio-logo-color-3-1

Sapio Sciences

The ELN&ndash;AI Disconnect in Modern Pharma

compendium-thumbnail

Female medical worker wearing lab coat while working in laboratory

89591-istock-2148841134-2400x1200-2400-x-1200

calira-logo

Calira

Rethinking ROI for Laboratory Equipment

Elemental analysis of urine thumbnail image

elemental-analysis-of-urine-thumb

Laboratory biochemical analysis test tubes

Stuart Pengelley

Articles by Stuart Pengelley

The Role of TIMS-MS in Ensuring High Purity in Biopharmaceuticals

How to Build Trust Into Every Lab Result

Sponsored

A New Twist on Comfort and Control with the BRAND® Transferpette® pro Pipette

The ELN–AI Disconnect in Modern Pharma

Rethinking ROI for Laboratory Equipment

Run Toxic, Nutritional, and Implant Markers in a Single Urine Panel