Biological safety cabinets (BSCs) are enclosures that protect users and the environment from biohazards by removing particulates and aerosolized pathogens from the work area through HEPA filtration, then recirculate or exhaust the purified air, hence, cleansing the workspace air.
BSCs provide protection to users/operators and/or samples. Whether performing research or production activities, the proper degree of protection should be maintained. The protection required by these types of activities is defined as biosafety levels.
Top 5 Questions You Should Ask When Buying a Biological Safety Cabinet (BSC or MSC)

1. Do the samples/specimens/cultures need to be protected from environmental particulates? Answering this question determines what type of BSC you require.
2. Are chemicals involved in your application? Hazardous (toxic or volatile) Vapors are not filtered by the HEPA/ ULPA filters found in BSCs. Different BSCs designs are available.
3. What are your size limits? Know what the maximum space allotment is so that you don’t end up with equipment that is too big for your lab, or so small that you can’t work.
4. Does your procedure require modifications to the equipment that are uncommon? BSCs should be built to an appropriate standard and listed by a testing agency. Some modifications can lead to the equipment being unsafe; reputable manufacturers will not provide such alterations.
5. Cost is always a concern. Avoid looking at the sticker price of a BSC; inquire instead about the lifetime cost of each BSC. This includes energy savings, service life, and a proven product track record.
The levels of containment within respondents’ labs based on our latest survey data:
Containment level 1 | 41% |
Containment level 2 | 49% |
Containment level 3 | 8% |
Containment level 4 | 2% |
Types of Biological Safety Cabinet respondents are using:
Class I | 29% |
Class II | 60% |
Class III | 10% |
Other | 1% |
Respondents’ thoughts on the following safety statements regarding BSCs:
Agree & Strongly Agree | Disagree & Strongly Disagree | |
All biological safety cabinets have been tested within the past year | 79% | 21% |
Test labels are properly affixed to the biological safety cabinets tested | 79% | 21% |
Storage in biological safety cabinets is kept to a minimum and is placed so as not to impede proper airflow | 85% | 15% |
Workers using biohazards, toxins and regulated carcinogens have received special training | 74% | 26% |
Rooms and cabinets containing regulated carcinogens, biohazards and radioactive materials are properly labeled | 87% | 13% |
Top ten factors/features that influence the decision-making process when buying a biological safety cabinet:
Important | |
Ease of Use | 93% |
Safety | 93% |
Low maintenance/operating costs | 89% |
Controlled airflow | 86% |
Price | 84% |
Service and support | 79% |
Warranty | 77% |
Ergonomic design | 74% |
Energy efficiency | 73 |
Ease of installation | 69% |
Recently Released Biological Safety Cabinets (BSC or MSC)
Purifier® CellLogic®
• Fits the specific needs of delicate cell research while also providing protection from hazardous particulates such as agents that require Biosafety Level 1, 2 or 3
• Accommodates a user’s microscope while still conforming to strict NSF® specifications through Scope-Ready™ option
• Temp-Zone™ option also available, allowing heated or chilled samples to remain at optimum temperature
Labconco
www.labconco.com
BioChemGARD e3
• Operates at only 664 CFM, minimizing noise and cutting power requirements
• Reduces the overall annual cost of operation by 49%
• Motor blower reserve is at least 420%, extending the filter life for less downtime
• Allows for faster, simpler maintenance
• Engineered specifically for laboratories that need containment and removal of vapors, mists and particulates
The Baker Company
www.bakerco.com
CellGard HD ES NU-481
• Incorporates NuAire’s existing technology and new DC ECM technology to give users the best value
• Requires less energy to operate, has a longer filter life and the lowest possible noise and vibration
• TouchLink™ Electronic Control System monitors and controls all cabinet functions
• Supplies an ergonomically correct environment and safety effective work zone
NuAire
www.nuaire.com
1300 Series
• Available with choices of stainless steel or SmartCoat interiors
• Supply and exhaust blowers adapt in real time to provide the correct airflow parameters and maintain a safe working environment
• Digital Airflow Verification (DAVe) system also increases safety
• Brushless DC motors reduce energy consumption, heat output, and noise
Thermo Fisher Scientific
www.thermoscientific.com
Biological Safety Cabinet Manufacturers
Air Science USA | www.air-science.com |
AirClean Systems | www.aircleansystems.com |
Captair | www.captair.com |
Erlab | www.erlab.com |
ESCO | www.escoglobal.com |
Flow Sciences | www.flowsciences.com |
Germfree | www.germfree.com |
HEMCO | www.hemcocorp.com |
Kewaunee Scientific | www.kewaunee.com |
Labconco | www.labconco.com |
Microzone | www.microzone.com |
Mystaire Misonix | www.misonix.com |
NuAire | www.nuaire.com |
Sentry Air Systems | www.sentryair.com |
Terra Universal | www.terrauniversal.com |
The Baker Company | www.bakerco.com |
Thermo Fisher Scientific | www.thermoscientific.com |
Z-sciences | www.z-sciences.com |